Results 91 to 100 of about 1,295,073 (340)

Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments

open access: yesFEBS Open Bio, EarlyView.
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau   +3 more
wiley   +1 more source

Epidemiological study of health effects in Fukushima Emergency Workers: Progress report on the Health Examination Study, 2016-2019

open access: yesEnvironmental Advances, 2022
To clarify the long-term health effects from radiation exposure in emergency workers who responded to the radiation accident at the Fukushima Daiichi Nuclear Power Plant of Tokyo Electric Power Company, which was hit by a tsunami caused by the 2011 off ...
Hiroko Kitamura   +3 more
doaj  

FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair

open access: yesCell Reports, 2014
The Fanconi anemia (FA) pathway is critically involved in the maintenance of hematopoietic stem cells and the suppression of carcinogenesis. A key FA protein, FANCD2, is monoubiquitinated and accumulates in chromatin in response to DNA interstrand ...
Junya Unno   +11 more
doaj   +1 more source

Radiation effects in reindeer

open access: yesRangifer, 1990
With the present level of radiocesium contamination, direct radiation effects have been hypothesised.
openaire   +4 more sources

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Radiation reaction effects on ion acceleration in laser foil interaction [PDF]

open access: yesarXiv, 2009
Radiation reaction effects on ion acceleration in laser foil interaction are investigated via analytical modeling and multi-dimensional particle-in-cell simulations. We find the radiation effects are important in the area where some electrons move backwards due to static charge separation field at the laser intensity of 1022 W=cm2.
arxiv  

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

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