Results 91 to 100 of about 14,661,451 (396)

Potential benefits of cool roofs in reducing heat-related mortality during heatwaves in a European city

open access: yesEnvironment International, 2019
Hot weather can exacerbate health conditions such as cardiovascular and respiratory diseases, and lead to heat stroke and death. In built up areas, temperatures are commonly observed to be higher than those in surrounding rural areas, due to the Urban ...
H.L. Macintyre, C. Heaviside
doaj   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Direct radiation-induced effects on dental hard tissue

open access: yesRadiation Oncology, 2019
BackgroundRadiation caries is a complication of radiotherapy characterized by enamel erosion and dentin exposure. The mechanisms of characteristic radiation caries formation are not well-understood.
Hui Lu   +6 more
semanticscholar   +1 more source

Ultraviolet radiation effects [PDF]

open access: yes
Solar ultraviolet testing was not developed which will provide highly accelerated (20 to 50X) exposures that correlate to flight test data. Additional studies are required to develop an exposure methodology which will assure that accelerated testing can ...
Slemp, Wayne S.
core   +1 more source

Radiation tolerant silicon nitride insulated gate field effect transistors [PDF]

open access: yes, 1969
Metal-Insulated-Semiconductor Field Effect Transistor /MISFET/ device uses a silicon nitride passivation layer over a thin silicon oxide layer to enhance the radiation tolerance.
Newman, P. A.
core   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

open access: yesFEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh   +2 more
wiley   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

open access: yesFEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda   +7 more
wiley   +1 more source

Colorectal cancers associated with mismatch repair deficiency

open access: yesFrontiers in Medicine
This review aims to summarize the latest updates in the prevention, diagnosis, treatment and management of colorectal cancers (CRCs) associated with mutation(s) or alteration(s) in the DNA mismatch repair (MMR) genes.
Mingzhu Sun   +4 more
doaj   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Space Weather Effects in the Earth’s Radiation Belts

open access: yes, 2018
The first major scientific discovery of the Space Age was that the Earth is enshrouded in toroids, or belts, of very high-energy magnetically trapped charged particles.
D. Baker   +5 more
semanticscholar   +1 more source

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