Results 71 to 80 of about 843,490 (307)

Are Nanoporous Materials Radiation Resistant?

Nano Letters, 2011
The key to perfect radiation endurance is perfect recovery. Since surfaces are perfect sinks for defects, a porous material with a high surface to volume ratio has the potential to be extremely radiation tolerant, provided it is morphologically stable in a radiation environment. Experiments and computer simulations on nanoscale gold foams reported here
Bringa, Eduardo Marcial, Monk, J. D., Caro, A., Misra, A., Zepada Ruiz, L., Duchaineau, M., Abraham, F., Nastasi, M., Picraux, S.T., Wang, Y.Q., Farkas, D.   +10 more
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Application of numerical methods to determine some parameters of radiation embrittlement of borosilicate glass

Қарағанды университетінің хабаршысы. Физика сериясы
In this paper, a numerical method for determining the parameters of radiation embrittlement in borosilicate glass is proposed. The method is based on analyzing the changes in the mechanical properties of the material atoms, the fluence Ф and the energy ...
Ш. М. Кажыкенов, Г. У. Ерболатова, А. К. Тусупбекова   +2 more
doaj   +1 more source

RADIATION RESISTANCE OF COMPOSITE SCINTILLATORS

Problems of Atomic Science and Technology, 2019
Radiation resistance of composite scintillators containing grains of organic or inorganic single crystals has been analysed. The analysis is based on the study of composite scintillators containing grains Gd2SiO5:Ce (GSO:Ce), Gd2Si2O7:Ce (GPS:Ce), Al2O3:Ti, Y2SiO5:Ce (YSO:Ce) or Y3Al5O12:Ce (YAG:Ce).
Boyarintsev, A.Yu., Galunov, N.Z., Gerasymov, Ia.V., Gorbacheva, T.E., Grinyov, B.V., Karavaeva, N.L., Khabuseva, S.U., Krech, A.V., Levchuk, L.G., Martynenko, E.V., Popov, V.F., Sidletskiy, O.Ts., Tarasenko, O.A.   +12 more
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Circuit Modeling of the Impact of Heavy Charged Particles on Transient Processes in Bipolar Analog Microcircuits

Доклады Белорусского государственного университета информатики и радиоэлектроники
One of the factors causing the failure of spacecraft integrated circuits is exposure to heavy charged particles. The entry of heavy charged particles into electronic devices leads to the appearance of single event transients (short current pulses), which
O. V. Dvornikov, V. A. Tchekhovski, I. Yu. Lovshenko, Trong Thanh Nguyen   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Collisionless reconnection using Alfvén wave radiation resistance [PDF]

, 1998
Patchy magnetic reconnection involves transient field-aligned current filaments. The spatial localization, transient time-dependence, and orientation of these current filaments means they must radiate torsional Alfvén waves. Radiation of wave energy does
Bellan, P. M.
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source