Results 61 to 70 of about 349,910 (312)

Understanding the Radiation Resistance Mechanisms of Nanocrystalline Metals from Atomistic Simulation

Metals, 2021
Metallic materials produce various structural defects in the radiation environment, resulting in serious degradation of material properties. An important way to improve the radiation-resistant ability of materials is to give the microstructure of ...
Liang Zhang
doaj   +1 more source

RADIATION RESISTANCE OF COMPOSITE SCINTILLATORS

Problems of Atomic Science and Technology, 2019
Radiation resistance of composite scintillators containing grains of organic or inorganic single crystals has been analysed. The analysis is based on the study of composite scintillators containing grains Gd2SiO5:Ce (GSO:Ce), Gd2Si2O7:Ce (GPS:Ce), Al2O3:Ti, Y2SiO5:Ce (YSO:Ce) or Y3Al5O12:Ce (YAG:Ce).
Boyarintsev, A.Yu., Galunov, N.Z., Gerasymov, Ia.V., Gorbacheva, T.E., Grinyov, B.V., Karavaeva, N.L., Khabuseva, S.U., Krech, A.V., Levchuk, L.G., Martynenko, E.V., Popov, V.F., Sidletskiy, O.Ts., Tarasenko, O.A.   +12 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Sound radiation from perforated plates [PDF]

, 2008
Perforated plates are quite often used as a means of engineering noise control to reduce the sound radiated by structures. However, there appears to be a lack of representative models to determine the sound radiation from a perforated plate.
Putra, Azma
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Evaluation of Radiation Thermal Resistances in Industrial Motors [PDF]

, 2006
This paper deals with the role of the radiation thermal resistances in industrial motors and describes a test set useful for the resistance evaluation. The test set is based on a vacuum chamber and on a numerical acquisition system, and the resistances ...
Parvis, Marco, Vallan, Alberto, Boglietti, Aldo, Cavagnino, Andrea   +3 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

DNA Damage Protection for Enhanced Bacterial Survival Under Simulated Low Earth Orbit Environmental Conditions in Escherichia coli

Frontiers in Microbiology, 2021
Some organisms have shown the ability to naturally survive in extreme environments, even outer space. Some of these have natural mechanisms to resist severe DNA damage from conditions such as ionizing and non-ionizing radiation, extreme temperatures, and
Jaume Puig, Jaume Puig, Nastassia Knödlseder, Nastassia Knödlseder, Jaume Quera, Jaume Quera, Jaume Quera, Manuel Algara, Manuel Algara, Manuel Algara, Marc Güell, Marc Güell   +11 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source