Results 41 to 50 of about 843,490 (307)

Radiation-induced FAP + fibroblasts are involved in keloid recurrence after radiotherapy

Frontiers in Cell and Developmental Biology, 2022
Background: Keloid scars (KSs), which are composed of abnormal hyperplastic scar tissue, form during skin wound healing due to excessive fibroblast activation and collagen secretion.
Yan Gao, Xue Hou, Yuyin Dai, Ting Yang, Kexin Chen   +4 more
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Effect of graphene quantum dots on the radiation resistance of epoxy resin

Fushe yanjiu yu fushe gongyi xuebao
Investigations on the damage and degradation mechanisms of epoxy resin under a high-energy irradiation and improvement in its stability in irradiation environments are crucial to expand the application of epoxy resin in numerous fields including the ...
HOU Jinxia, LIU Shengkai, PEI Xiaoyuan, WANG Wei, YIN Yue, ZHOU Xinke, XU Zhiwei   +6 more
doaj   +1 more source

Cetuximab enhances radiosensitivity of esophageal squamous cell carcinoma cells by G2/M cycle arrest and DNA repair delay through inhibiting p‐EGFR and p‐ERK

Thoracic Cancer, 2023
Background Although radiotherapy has improved local control in esophageal squamous cell carcinoma (ESCC), a considerable number of patients still experience relapse due to resistance.
Guifang Zhao, Liwen Feng, Ting Ye, Yanshen Liu, Li Fan, Chengzhi Ye, Jing Chen   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Radiation tolerance of nanocrystalline ceramics: insights from Yttria Stabilized Zirconia. [PDF]

, 2015
Materials for applications in hostile environments, such as nuclear reactors or radioactive waste immobilization, require extremely high resistance to radiation damage, such as resistance to amorphization or volume swelling.
Castro, Ricardo HR, Dey, Sanchita, Drazin, John W, Holesinger, Terry G, Uberuaga, Blas P, Valdez, James A, Wang, Yongqiang   +6 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Genomic Insights into the Radiation-Resistant Capability of Sphingomonas qomolangmaensis S5-59^T and Sphingomonas glaciei S8-45^T, Two Novel Bacteria from the North Slope of Mount Everest

Microorganisms, 2022
Mount Everest provides natural advantages to finding radiation-resistant extremophiles that are functionally mechanistic and possess commercial significance.
Yang Liu, Xiaowen Cui, Ruiqi Yang, Yiyang Zhang, Yeteng Xu, Guangxiu Liu, Binglin Zhang, Jinxiu Wang, Xinyue Wang, Wei Zhang, Tuo Chen, Gaosen Zhang   +11 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Understanding the Radiation Resistance Mechanisms of Nanocrystalline Metals from Atomistic Simulation

Metals, 2021
Metallic materials produce various structural defects in the radiation environment, resulting in serious degradation of material properties. An important way to improve the radiation-resistant ability of materials is to give the microstructure of ...
Liang Zhang
doaj   +1 more source