Results 41 to 50 of about 4,316,557 (292)

Mechanophore activation enhanced by hydrogen bonding of diarylurea motifs: An efficient supramolecular force‐transducing system

open access: yesAggregate, 2021
Macromolecules are efficient as mechanical transducers for mechanically induced chemical bond cleavage reactions. Although various classes of polymers have been studied as effective mechanical‐force transducers for mechanophores, alternatives to polymer ...
Jumpei Kida   +2 more
doaj   +1 more source

La naturaleza del mal: un problema para el ser humano

open access: yesRevista Filosofía UIS, 2022
El trabajo hace un breve desarrollo del problema del mal y se aproxima a las dos concepciones que se tienen sobre él: el mal amplio y el mal estricto. Se enmarca tanto dentro de la tradición del pensamiento de Arendtiano como de su idea de la banalidad ...
Juan José Láriz Durón
doaj   +1 more source

Three-electron two-centred bonds and the stabilisation of cationic sulfur radicals [PDF]

open access: yes, 2014
Electronic communication in biological systems is fundamental to understanding protein signalling and electron hopping pathways. Frequently studied examples are cationic radical methionine and its functional derivatives.
Carbery, DR, Hendon, CH, Walsh, A
core   +1 more source

O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease

open access: yesMolecular Brain, 2017
Post-translational modification on protein Ser/Thr residues by O-linked attachment of ß-N-acetyl-glucosamine (O-GlcNAcylation) is a key mechanism integrating redox signaling, metabolism and stress responses.
Willayat Y. Wani   +8 more
doaj   +1 more source

Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer.

open access: yesNew England Journal of Medicine, 2002
BACKGROUND We conducted 20 years of follow-up of women enrolled in a randomized trial to compare the efficacy of radical (Halsted) mastectomy with that of breast-conserving surgery.
U. Veronesi   +7 more
semanticscholar   +1 more source

Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease

open access: yesRedox Biology, 2014
Oxidative stress including DNA damage, increased lipid and protein oxidation, are important features of aging and neurodegeneration suggesting that endogenous antioxidant protective pathways are inadequate or overwhelmed.
Samantha Giordano   +2 more
doaj   +1 more source

Radical-Enhanced Chinese Character Embedding

open access: yes, 2014
We present a method to leverage radical for learning Chinese character embedding. Radical is a semantic and phonetic component of Chinese character. It plays an important role as characters with the same radical usually have similar semantic meaning and ...
Ji, Zhenzhou   +5 more
core   +1 more source

Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in the pathophysiology of insulin resistance and type 2 diabetes

open access: yesJournal of Biomedical Science, 2017
Metabolic diseases such as obesity, type 2 diabetes (T2D) and insulin resistance have attracted great attention from biomedical researchers and clinicians because of the astonishing increase in its prevalence.
Chih-Hao Wang, Yau-Huei Wei
doaj   +1 more source

Radical distinction: Support for radical left and radical right parties in Europe [PDF]

open access: yesEuropean Union Politics, 2017
Support for radical parties on both the left and right is on the rise, fueling intuition that both radicalisms have similar underpinnings. Indeed, existing studies show that radical left and right voters have overlapping positions and preferences. In this article, however, we focus on the differences in the voting bases of such parties.
Rooduijn, M.   +3 more
openaire   +6 more sources

Triggering redox activity in a thiophene compound: radical stabilization and coordination chemistry [PDF]

open access: yes, 2006
The synthesis, metalation, and redox properties of an acyclic bis(iminothienyl)methene L− are presented. This π-conjugated anion displays pronounced redox activity, undergoing facile one-electron oxidation to the acyclic, metal-free, neutral radical L ...
Davison   +46 more
core   +2 more sources

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