Results 121 to 130 of about 88,161 (270)

Incidence and prognostic implications of PSA relapse after radical radiotherapy for prostate cancer: a population‐based study

BJU International, EarlyView.
Objective To estimate risk of prostate‐specific antigen (PSA) relapse after radical radiotherapy (RT) for prostate cancer (PCa), and risk of PCa death after relapse according to Gleason score and time to relapse. Patients and Methods Men in the National Prostate Cancer Register of Sweden who underwent primary radical RT in 2007–2024 were followed until
Paolo Zaurito, Hans Garmo, Rolf Gedeborg, Mats Alhberg, Stefan Carlsson, Camilla Thellenberg, David Robinson, Pär Stattin, Marcus Westerberg   +8 more
wiley   +1 more source

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

BJU International, EarlyView.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam, Bishoy Hanna, Stuart Jackson, Stephen McCombie, George McClintock, Matthew J. Roberts, Jeremy Teoh, Mohan Arianayagam, Bertram Canagasingham, Ahmed Saeed Goolam, Nicola Jeffery, Matthew Winter, Mohamed Khadra, Raymond Ko, Nicholas Mehan, Isaac Thangasamy, Celi Varol   +16 more
wiley   +1 more source

Diagnostic accuracy and outcomes of lymph node staging in intermediate‐risk prostate cancer

BJU International, EarlyView.
Objective To evaluate the diagnostic performance of different staging modalities and oncological outcomes in patients with intermediate‐risk (IR) prostate cancer (PCa) undergoing radical prostatectomy (RP) with pelvic lymph node dissection (PLND).
Christopher Kniep, Tobias Maurer, Ben Frederik Hartwieg, Philipp Mandel, Mike Wenzel, Fabian Falkenbach, Kristian Krpina, Lars Budäus, Alexander Haese, Georg Salomon, Thomas Steuber, Markus Graefen, Derya Tilki, Felix Preisser   +13 more
wiley   +1 more source

Extraperitoneal single‐site robot‐assisted radical prostatectomy with extended pelvic lymph node dissection: technique and experience

BJU International, Volume 135, Issue 4, Page 700-705, April 2025.
Yubo Wang, Mingzhao Li, Kai Yao, Zhuyinjun Zong, Yifan Chang, Yongda Liu, Chao Cai, Fadi Mousa Al Kalailah, Shancheng Ren, Guohua Zeng, Di Gu   +10 more
wiley   +1 more source

Feasibility and workflow analysis of confocal microscopy in robot‐assisted prostatectomy

BJU International, EarlyView.
Objectives To assess the diagnostic accuracy, workflow feasibility, and downstream compatibility of fluorescence confocal microscopy (Histolog® Scanner [HS]; SamanTree Medical SA, Lausanne, Switzerland) compared with frozen section (FS) for intraoperative margin evaluation (IME) during nerve‐sparing robot‐assisted radical prostatectomy (RARP). Patients
Kristijan Skok, Lukas Scheipner, Sebastian Mannweiler, Karl Kashofer, Ariane Aigelsreiter, Ivana Milosevic, Conrad Leitsmann, Herbert Augustin, Martina Rößmann‐Tsybrovskyy, Sascha Ahyai, Bernadette Liegl‐Atzwanger, Johannes Mischinger   +11 more
wiley   +1 more source

Macroscopical and histological characterization of the perineal membrane and deep perineal pouch

Journal of Anatomy, EarlyView.
The existence of the deep transverse perineal muscle remains controversial. While the macroscopic appearance of the tissue in the deep perineal pouch differs between men and women, the differences in the histological composition of this fibromuscular plate is still unclear.
Morten Kampelmann, Carina Grindley, Christian Mühlfeld, Andreas Schmiedl   +3 more
wiley   +1 more source

Patient blood management and surgery: Impact of new surgical techniques on transfusion needs

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Patient blood management (PBM) is a multidisciplinary approach aimed at reducing the use of blood products. It considers the patient's own blood as a valuable resource to preserve and seeks to avoid the routine use of transfusions to treat anaemia.
Francois Ansart, France Pirenne
wiley   +1 more source

Impact of exercise training on tumour‐infiltrating T cells in human prostate cancer: A secondary analysis of a randomized controlled trial (PRO‐TEST)

Experimental Physiology, EarlyView.
Abstract Exercise training reduces tumour growth by increasing tumour‐infiltrating T‐cell density in preclinical models. However, it remains unknown whether exercise training can modify intratumoural T cells in humans.The aim of this study was to compare the effects of an exercise training intervention versus control on human prostate intratumoural T ...
Simon Nørskov Thomsen, Emil Wriedt, Marianne Gardar Stærk, Sissal Sigmundsdottir Djurhuus, Birgitte Grønkær Toft, Sabrina Wielsøe, Andreas Røder, Thomas Hasselager, Peter Busch Østergren, Henrik Jakobsen, Klaus Brasso, Jesper Frank Christensen, Louise Lang Lehrskov, Casper Simonsen   +13 more
wiley   +1 more source

Robot‐Assisted Radical Prostatectomy in a Patient With a Rectal Fistula Following Hydrogel Spacer Placement

IJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction The polyethylene glycol‐based hydrogel spacer (SpaceOAR; Boston Scientific, Marlborough, MA, USA) reduces the rectal dose during prostate radiotherapy and rarely leads to rectal ulceration or fistula formation. We report a case in which robot‐assisted radical prostatectomy (RARP) was successfully performed following this rare ...
Erika Ikezoe, Yasukazu Nakanishi, Gaku Okumura, Shu Gozu, Tomonori Kanagawa, Naoki Imasato, Kohei Hirose, Madoka Kataoka, Shugo Yajima, Hitoshi Masuda   +9 more
wiley   +1 more source

A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells

MedComm, Volume 7, Issue 3, March 2026.
HS1002, a new peptide targeting GnRHR and hTERT, demonstrates significant Anticancer activity in prostate cancer cells. The mechanism of HS1002 can be attributed to the reduction of serum testosterone levels by desensitization of GnRHR, the downregulation of hTERT expression and telomerase activity, and the enhancement of Anticancer immunity.
Jae Hyeon Park, Joo Chan Lee, Swati Sharma, Chunxue Jiang, Haeun Lee, Hyun‐Ju Park, Hyung Sik Kim   +6 more
wiley   +1 more source