Results 131 to 140 of about 830,959 (241)

Prostate‐specific membrane antigen (PSMA)‐PET‐avid prostate cancers show stronger PSMA immunohistochemistry staining on biopsy cores

BJU International, EarlyView.
Jonathon Carll, Henry Yen‐Cheng Pan, Nathan Lawrentschuk, Andrew Ryan   +3 more
wiley   +1 more source

Segment‐based comparison of multiparametric MRI, Gallium‐68‐PSMA‐PET/CT and combined imaging with histopathology in prostate cancer

BJU International, EarlyView.
Objectives To compare the segment‐based diagnostic performance of multiparametric magnetic resonance imaging (mpMRI), Gallium‐68‐prostate‐specific membrane antigen‐positron emission tomography/computed tomography (68Ga‐PSMA‐PET/CT), for detecting histopathologically confirmed prostate cancer (PCa).
Clarissa J. Schmidt, Marit Bernhardt, Glen Kristiansen, Florian C. Gaertner, Barbara Kreppel, Markus Essler, Julian A. Luetkens, Ulrike Attenberger, Michael Anspach, Carsten‐Henning Ohlmann, Stefan Hauser, Jörg Ellinger, Manuel Ritter, Philipp Krausewitz   +13 more
wiley   +1 more source

Opposing roles of acid phosphatase 1 (ACP1) and ACP3 in prostate cancer progression

BJU International, EarlyView.
Objectives To evaluate the roles of intracellular acid phosphatase 1 (ACP1) and ACP3 expression as biomarkers of prostate cancer progression through a systematic review and meta‐analysis assessing associations with disease presence, tumour aggressiveness, and patient prognosis.
Alessandra V. de S. Faria, Carmen V. Ferreira‐Halder, Maikel P. Peppelenbosch, Gwenny M. Fuhler   +3 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Aging‐related morphological changes in the obturator internus and levator ani

Journal of Anatomy, EarlyView.
A cross‐sectional MRI‐based morphometric analysis of 27 women aged 25–83 years revealed age‐associated morphological differences in the obturator internus and levator ani. Older age was associated with relative superior narrowing of the obturator internus, inferior displacement of its groove and medial eminence, a more vertical orientation of the ...
Satoru Muro, Junichi Tsuchiya, Takuya Ibara, Akimoto Nimura, Keiichi Akita   +4 more
wiley   +1 more source

The effect of time from biopsy to radical prostatectomy on adverse pathologic outcomes

, 2019
Premal Patel,1 Ryan Sun,1 Benjamin Shiff,1 Kiril Trpkov,2 Geoffrey Thomas Gotto3 1Section of Urology, University of Manitoba, Winnipeg, MB, Canada; 2Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada; 3Department ...
Patel P, Shiff B, Trpkov K, Sun R, Gotto GT   +4 more
core  

Adrenergic Contraction of Human Prostate Tissues Is Maintained Under the Rab GTPase Inhibitors Nexhinib20 and CID1067700

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT α1‐Adrenoceptors are an important drug target in benign prostatic hyperplasia (BPH) and have been intensively studied at the expression level, but their posttranslational regulation in the prostate is widely unknown. Here we examined modulation of prostate smooth muscle contractions by inhibitors for RabGTPases, which are involved in ...
Luca Troffer, Peibin Cen, Michael Brandstetter, Yajie Xu, Patrick Keller, Leo Stadelmeier, Philipp Weinhold, Alexander Tamalunas, Christian G. Stief, Martin Hennenberg   +9 more
wiley   +1 more source

Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia

The Journal of Latin American and Caribbean Anthropology, Volume 31, Issue 4, December 2026.
ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley   +1 more source

An X‐ray micro‐CT protocol enables non‐destructive 3D visualization of glandular architecture in archived paraffin‐embedded prostate cancer tissue

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract The prostate is organized as a complex glandular network, and prostate cancer is accompanied by architectural changes that cannot always be inferred from two‐dimensional (2D) histology. The study of these features in three dimensions (3D) in cancerous tissue is important because glandular features have shown potential value for disease ...
Santiago Laguna‐Castro, Erna Mäkinen, Teemu Tolonen, Antti Kaipia, Jari Hyttinen   +4 more
wiley   +1 more source

Automated offline adaptive radiotherapy through CBCT imaging: A multidimensional feasibility study of hypersight and iterative CBCT

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Offline adaptive radiotherapy (OffART) offers potential dosimetric and clinical advantages by adjusting planned dosimetry in response to systematic patient changes throughout treatment, however implementation is associated with an increased labor burden.
Ben R. Archibald‐Heeren, Aidan Leong, Nigel Middlebrook, Peter Phung, Sarah Hauville, Yunfei Hu, Gayan Singappulige, Trent J Aland   +7 more
wiley   +1 more source