Results 131 to 140 of about 88,800 (280)

Genetic Predictors of Progression and Skin Rash in Japanese mCSPC Patients Treated With Apalutamide: CUARTET Study

Cancer Science, EarlyView.
In patients with mCSPC treated with apalutamide plus ADT, baseline ctDNA predicted earlier progression to CRPC and worse overall survival. Exploratory genome‐wide analysis identified 12 SNPs associated with apalutamide‐related skin rash. ABSTRACT Despite promising evidence of the efficacy of the androgen deprivation therapy (ADT) plus apalutamide in ...
Masaki Shiota, Taku Naiki, Koji Hatano, Akira Yokomizo, Hiroaki Tsuchiya, Yoko Takahashi, Taku Nakayama, Masaki Yoshida, Hirotsugu Uemura   +8 more
wiley   +1 more source

Prostate‐specific membrane antigen (PSMA)‐PET‐avid prostate cancers show stronger PSMA immunohistochemistry staining on biopsy cores

BJU International, EarlyView.
Jonathon Carll, Henry Yen‐Cheng Pan, Nathan Lawrentschuk, Andrew Ryan   +3 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Follow-up of prostatectomy versus observation for early prostate cancer [PDF]

, 2017
Andriole, Gerald L, Aronson, William J, Barry, Michael J, Brawer, Michael K, Culkin, Daniel, Jones, Karen M, Wheeler, Thomas, Wilt, Timothy J   +7 more
core   +3 more sources

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

Histopathology, EarlyView.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao, Jun Yao, Hossein Hosseini, Ezra Baraban, Ruihe Lin, Charles C. Guo, Lei Huo, Wei Lu, Khaja Khan, Shufang Wang, Luisa Maren Solis Soto, Qingqing Ding   +11 more
wiley   +1 more source

Platform‐Specific Learning Curves in Robotic‐Assisted Total Knee Arthroplasty: A Systematic Review

Orthopaedic Surgery, EarlyView.
This systematic review compared learning curves for robotic‐assisted total knee arthroplasty across MAKO, NAVIO, and ROSA platforms. NAVIO required the fewest cases to proficiency, while radiographic accuracy and complication rates remained stable. Patient‐reported outcomes were inconsistently reported. ABSTRACT Robotic‐assisted total knee arthroplasty
Ryhan Divyang Patel, Praneshraja Ganesaraja, Kapil Sugand, Sree Kanakala, Indi Gupte, Srikar Reddy Namireddy, Saran Singh Gill   +6 more
wiley   +1 more source

Impact of exercise training on tumour‐infiltrating T cells in human prostate cancer: A secondary analysis of a randomized controlled trial (PRO‐TEST)

Experimental Physiology, EarlyView.
Abstract Exercise training reduces tumour growth by increasing tumour‐infiltrating T‐cell density in preclinical models. However, it remains unknown whether exercise training can modify intratumoural T cells in humans.The aim of this study was to compare the effects of an exercise training intervention versus control on human prostate intratumoural T ...
Simon Nørskov Thomsen, Emil Wriedt, Marianne Gardar Stærk, Sissal Sigmundsdottir Djurhuus, Birgitte Grønkær Toft, Sabrina Wielsøe, Andreas Røder, Thomas Hasselager, Peter Busch Østergren, Henrik Jakobsen, Klaus Brasso, Jesper Frank Christensen, Louise Lang Lehrskov, Casper Simonsen   +13 more
wiley   +1 more source

Characterizing the Diffusion Properties of Prostate Tissue Using Paired MR Microscopy and Multidimensional Diffusion MRI

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 349-365, July 2026.
ABSTRACT Purpose To characterize the diffusion properties of prostate epithelium and stroma in benign tissue and cancer. Methods Paired MR microscopy (20 μm) and multidimensional diffusion MRI (dMRI) (160 μm, b = 1000–2000 s/mm2, ∆ = 15–120 ms) were performed at 16.4 T on 17 fixed prostate tissue samples (14× benign, 2× Gleason 3 + 3, 1× Gleason 4 + 4).
Adam Phipps, Nyoman D. Kurniawan, Geoff Watson, Paul Sved, Samson Dowland, Eleftheria Panagiotaki, David Atkinson, Roger Bourne   +7 more
wiley   +1 more source

Hepatocyte growth factor/c‐Met signaling axis in human diseases: Mechanistic insights and therapeutic potential

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun, Hao Shu, Qian Zhang, Jishan Zheng, Yunyan Ma, Dengwang Chen, Jidong Zhang, Tao Song   +7 more
wiley   +1 more source

Needle-assisted laparoendoscopic single-site radical prostatectomy using a new series of steerable instruments : feasible option to overcome current limits? [PDF]

, 2018
Bauwens, Kevin, De Groote, Ruben, De Pauw, Tim, Dekuyper, Peter, Dewaele, Frank, Kalmar, Alain, Lumen, Nicolaas, Mottrie, Alexandre, Traen, Koen, Uvin, Pieter, Van Nieuwenhove, Yves, Van Roost, Dirk   +11 more
core   +2 more sources