Results 111 to 120 of about 4,478 (181)

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

A computer‐aided diagnosis tool in prostate cancer patients with biochemical recurrence using 18F‐PSMA PET/CT imaging

open access: yesMedical Physics, Volume 53, Issue 7, July 2026.
Abstract Background Prostate cancer (PCa) patients frequently experience biochemical recurrence (BCR) following definitive primary treatment. Although fluorine‐18–labeled prostate‐specific membrane antigen positron emission tomography/computed tomography (18F‐PSMA PET/CT) is an imaging modality that is highly sensitive for BCR, false‐positive findings ...
Ioanna Stamouli   +10 more
wiley   +1 more source

Characterizing the Diffusion Properties of Prostate Tissue Using Paired MR Microscopy and Multidimensional Diffusion MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 1, Page 349-365, July 2026.
ABSTRACT Purpose To characterize the diffusion properties of prostate epithelium and stroma in benign tissue and cancer. Methods Paired MR microscopy (20 μm) and multidimensional diffusion MRI (dMRI) (160 μm, b = 1000–2000 s/mm2, ∆ = 15–120 ms) were performed at 16.4 T on 17 fixed prostate tissue samples (14× benign, 2× Gleason 3 + 3, 1× Gleason 4 + 4).
Adam Phipps   +7 more
wiley   +1 more source

Magnetic Resonance Imaging at 14 Tesla of Prostate Biopsies Obtained after Prostatectomy

open access: yesNMR in Biomedicine, Volume 39, Issue 7, July 2026.
Fresh prostate biopsies were imaged using a 14 T vertical bore MRI scanner, and the effects of long gradient separation Δ (10–400 ms) were explored. At Δ longer than 10 ms, the percentage of voxels where the Akaike information criteria (AICc) favored a monoexponential model increased, and the apparent diffusion coefficient (ADC) lowered compared to Δ ...
Fredrik Langkilde   +4 more
wiley   +1 more source

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer

open access: yesThe Prostate, Volume 86, Issue 10, Page 1103-1114, July 2026.
ABSTRACT Background The management of intermediate‐risk early prostate cancer (PCa) is challenging due to the difficulty in distinguishing indolent from aggressive tumors. This study explores the association between genomic alterations and the tumor and its microenvironment (TME) and implications for disease progression. Methods We performed multi‐omic
William Lautert‐Dutra   +13 more
wiley   +1 more source

Temporal Patterns and Resolution of Toxicities Following Hypofractionated Salvage Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy

open access: yesThe Prostate, Volume 86, Issue 10, Page 1115-1123, July 2026.
ABSTRACT Background Hypofractionated salvage radiotherapy is increasingly used for biochemical recurrence of prostate cancer post‐prostatectomy, yet its toxicity profile remains underexplored. This study evaluates the incidence, timing, and resolution of treatment‐related toxicities in this setting.
Bum‐Sup Jang   +2 more
wiley   +1 more source

Lipid and Foam Cell Accumulation as Novel Pathological Features of Benign Prostatic Hyperplasia

open access: yesThe Prostate, Volume 86, Issue 10, Page 1157-1169, July 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) encompasses a heterogeneous set of pathological processes that instigate lower urinary tract symptoms (LUTS). Using a mouse model of steroid hormone imbalance–induced lower urinary tract dysfunction, we identified luminal lipid‐laden foamy macrophages, although their presence and contribution to ...
Dita Julianingsih   +9 more
wiley   +1 more source

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

open access: yesBJU International, Volume 138, Issue S2, Page S74-S80, July 2026.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam   +17 more
wiley   +1 more source

The prostate cancer electronic health (eHealth) literacy instrument: a tool for eHealth design and patient communication

open access: yesBJU International, Volume 138, Issue S2, Page S88-S96, July 2026.
Objective To describe the development and validation of the Prostate Cancer Electronic Health (eHealth) Literacy Instrument (P‐CeHLI). This is in response to: (i) a lack of clear and validated eHealth literacy measurement for men with prostate cancer; (ii) the unique information processing, decision making, and digital communication experience of men ...
Stuart Robert Jackson   +6 more
wiley   +1 more source

Iatrogenic ureteric injuries after abdominal surgery: a systematic review and meta‐regression from the European Association of Urology Endourology Section

open access: yesBJU International, Volume 138, Issue 1, Page 45-56, July 2026.
Objective To systematically evaluate management strategies and associated outcomes of iatrogenic ureteric injuries, focusing on clinical success, renal unit loss, and the need for subsequent endoscopic or reconstructive procedures. Patients and Methods A pre‐registered protocol (CRD420251184018) guided a comprehensive search of PubMed and EMBASE ...
Pietro Scilipoti   +17 more
wiley   +1 more source

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