Results 121 to 130 of about 789,461 (263)
BJU International, Volume 135, Issue 4, Page 700-705, April 2025.
Yubo Wang +10 more
wiley +1 more source
ASCT2 inhibition induces ROS accumulation and activates NRF2‐dependent xCT upregulation in prostate cancer. This adaptive response partially supports residual cystine acquisition and glutathione synthesis, whereas combined ASCT2 and xCT inhibition disrupts redox compensation and predominantly promotes apoptotic cell death.
Jiaxing Wei +9 more
wiley +1 more source
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini +4 more
wiley +1 more source
The combination of velocity‐compensated diffusion encoding, spiral readout and strong gradients enabled high‐quality prostate IVIM imaging, offering a promising framework for the development of reliable IVIM‐based biomarkers for prostate cancer detection, characterisation and monitoring.
Malwina Molendowska +6 more
wiley +1 more source
Management of De Novo miN1 Prostate Cancer in the PSMA‐PET Era
ABSTRACT Background Prostate‐specific membrane antigen positron emission tomography (PSMA‐PET) is reshaping nodal staging in prostate cancer by detecting regional lymph node metastases with greater accuracy than conventional imaging. This has created a new cohort of patients with N1M0 disease detectable only on advanced imaging, raising important ...
Thomas McMaster +11 more
wiley +1 more source
Australian General Practitioners' Understanding of PSA Testing Guidelines: A Survey‐Based Study
ABSTRACT PSA screening remains controversial, but evolving evidence and updated Australian guidelines now support informed testing decisions. Given GPs' key role in PSA screening, this study examines NSW GPs' understanding, attitudes and practices to identify gaps in applying current national recommendations.
Daniel Feng +5 more
wiley +1 more source
ABSTRACT The management of Peyronie's Disease (PD) remains a clinical challenge to urologists due to its dynamic and heterogeneous nature, variable psychosocial burden, with wide‐ranging treatments, both non‐surgical and surgical. Recent advances in Peyronie's disease (PD) include refined classification systems like PTNM that help facilitate ...
Justin K. Achua +5 more
wiley +1 more source
The effect of time from biopsy to radical prostatectomy on adverse pathologic outcomes
Premal Patel,1 Ryan Sun,1 Benjamin Shiff,1 Kiril Trpkov,2 Geoffrey Thomas Gotto3 1Section of Urology, University of Manitoba, Winnipeg, MB, Canada; 2Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada; 3Department ...
Patel P +4 more
core
ABSTRACT To evaluate the influence of prostate volume on the diagnostic accuracy of multiparametric MRI (mpMRI) in detecting clinically significant prostate cancer (ISUP Grade ≥ 2), using radical prostatectomy (RP) histopathology as the reference standard.
Matthieu Bryan Chun‐Hei Mo +5 more
wiley +1 more source

