Results 91 to 100 of about 3,002,287 (282)

RMechDB: A Public Database of Elementary Radical Reaction Steps. [PDF]

J Chem Inf Model, 2023
Tavakoli M, Chiu YTT, Baldi P, Carlton AM, Van Vranken D.   +4 more
europepmc   +1 more source

Cascade radical reaction of substrates with a carbon–carbon triple bond as a radical acceptor

Beilstein Journal of Organic Chemistry, 2013
The limitation of hydroxamate ester as a chiral Lewis acid coordination moiety was first shown in an intermolecular reaction involving a radical addition and sequential allylation processes.
Hideto Miyabe, Ryuta Asada, Yoshiji Takemoto   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Atmospheric Hydroxyl Radical Reaction Rate Coefficient and Total Environmental Lifetime of α-Endosulfan. [PDF]

Environ Sci Technol, 2023
Alarcon PC, Kitanovski Z, Padervand M, Pöschl U, Lammel G, Zetzsch C.   +5 more
europepmc   +1 more source

N-Nitroso products from the reaction of indoles with Angeli's salt [PDF]

, 2006
While nitroxyl (HNO) has been shown to engage in oxidation and hydroxylation reactions, little is known about its nitrosating potential. We therefore sought to investigate the kinetics of formation and identity of the reaction products of the classical ...
Peyrot, Fabienne, Feelisch, Martin, Claire Ducrocq, S. Bryan, Nathan, Ducrocq, Claire, Martin Feelisch, Bryan, Nathan S, O. Fernandez, Bernadette, Nathan S. Bryan, Fernandez, Bernadette O., Fabienne Peyrot, Bernadette O. Fernandez   +11 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Influence of Ring Strain on the Formation of Rearrangement vs Cyclization Isotwistane Products in the Acyl Radical Reaction of Bicyclo[2.2.2]octanone. [PDF]

Org Lett, 2023
Chen CM, Lin SK, Hsieh CT, Reddy JS, Teoh YN, Cheng MJ, Hsieh HP.   +6 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A Stable and Safe Form of Iodine Azide: Polymer-Bound Bisazidoiodate(I)

SynOpen, 2021
Vincent George, Andreas Kirschning
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source