Oxime derivatives : versatile reagents for radical-mediated syntheses of heterocycles [PDF]
, 2010 A summary of tin hydride mediated reactions in generating radicals in organic synthesis is presented, together with some of the many alternative methods now available for conducting radical reactions.
Portela-Cubillo, Fernando
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Chemistry Central Journal, 2012 Background Oxygen-base (O-base) oxidation in protein backbone is important in the protein backbone fragmentation due to the attack from reactive oxygen species (ROS).
Chen Hsing-Yu +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
En un lugar de la Mancha... : discurso pronunciado en la velada que se celebró en el Casino Republicano Radical la noche del 7 de mayo de 1905 con motivo del centenario del "Quijote" [PDF]
, 1905 Discurso pronunciado en la velada celebrada en el Casino Republicano Radical, el 7 de mayo de 1905, con motivo del centenario del QuijoteHay un ejemplar encuadernado con: El Quijote en las escuelas (Cervantina ...
Casino Republicano Radical (Valencia) +1 more
core
[Cu(bcp)(DPEphos)]+: A Versatile and Efficient Copper-Based Photoredox Catalyst and Photosensitizer
SynOpen, 2021 Samuel Oger +6 more
doaj +1 more source
Flow Giese reaction using cyanoborohydride as a radical mediator
Beilstein Journal of Organic Chemistry, 2013 Tin-free Giese reactions, employing primary, secondary, and tertiary alkyl iodides as radical precursors, ethyl acrylate as a radical trap, and sodium cyanoborohydride as a radical mediator, were examined in a continuous flow system.
Takahide Fukuyama +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Persistent Radical Effect in Living Radical Polymerization – Borderline Cases and Side-Reactions
CHIMIA, 2001 A theoretical analysis of the basic mechanism of living radical polymerization provides criteria for the rate constants required for optimized processes.
Hanns Fischer, Marc Souaille
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source