Results 1 to 10 of about 805,488 (283)

Setmelanotide – from genes to targeted therapy in some rare forms of obesity [PDF]

open access: yesFarmacja Polska, 2021
Obesity is a serious public health concern. It significantly affects an individual’s quality of life and is associated with an increased risk of developing other conditions, including diabetes, hypertension, and cardiovascular complications.
Dawid Frączkowski
doaj   +1 more source

The Modus Operandi of Hydrogen Sulfide(H2S)-Dependent Protein Persulfidation in Higher Plants

open access: yesAntioxidants, 2021
Protein persulfidation is a post-translational modification (PTM) mediated by hydrogen sulfide (H2S), which affects the thiol group of cysteine residues from target proteins and can have a positive, negative or zero impact on protein function.
Francisco J. Corpas   +4 more
doaj   +1 more source

Evidence of Paraoxonases 1, 2, and 3 Expression in Human Ovarian Granulosa Cells

open access: yesAntioxidants, 2021
Increasing evidence suggests that the antioxidant paraoxonase proteins, PON1, PON2, and PON3, have a role in reproduction and may be synthesized by ovarian cells.
Irantzu Pérez-Ruiz   +6 more
doaj   +1 more source

Radical Reactivity of Radical Ions in Solution. Radical--Radical and Radical--Substrate Coupling Mechanisms. [PDF]

open access: yesActa Chemica Scandinavica, 1998
The linear sweep voltammetry response to competitive radical ion-substrate coupling and radical ion dimerization mechanisms was determined by digital simulation. The simulations were carried out to mimic the conditions under which experimental studies had previously shown that the radical ion-substrate coupling mechanism is the preferred reaction ...
Vernon D. Parker   +7 more
openaire   +2 more sources

Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)

open access: yesFrontiers in Physiology, 2021
α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985.
Jesper Bergwik   +5 more
doaj   +1 more source

A Review of Manganese(III) (Oxyhydr)Oxides Use in Advanced Oxidation Processes

open access: yesMolecules, 2021
The key role of trivalent manganese (Mn(III)) species in promoting sulfate radical-based advanced oxidation processes (SR-AOPs) has recently attracted increasing attention.
Daqing Jia   +3 more
doaj   +1 more source

Antileishmanial Anthracene Endoperoxides: Efficacy In Vitro, Mechanisms and Structure-Activity Relationships

open access: yesMolecules, 2022
Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells.
Laura Machin   +7 more
doaj   +1 more source

Synthesis of Bis(3‐indolyl)methanes Mediated by Potassium tert‐Butoxide

open access: yesChemistryOpen, 2023
The indole moiety is an important N‐heterocycle found in natural products, and a key structural component of many value‐added chemicals including pharmaceuticals. In particular, bis(3‐indolyl)methanes (BIMs) are an important subgroup of indoles, composed
A. Sofia Santos   +5 more
doaj   +1 more source

Spectroscopy of free radicals and radical containing entrance-channel complexes in superfluid helium nano-droplets [PDF]

open access: yes, 2006
The spectroscopy of free radicals and radical containing entrance-channel complexes embedded in superfluid helium nano-droplets is reviewed. The collection of dopants inside individual droplets in the beam represents a micro-canonical ensemble, and as ...
Alkemade U   +22 more
core   +3 more sources

Sweet Pepper (Capsicum annuum L.) Fruits Contain an Atypical Peroxisomal Catalase That Is Modulated by Reactive Oxygen and Nitrogen Species

open access: yesAntioxidants, 2019
During the ripening of sweet pepper (Capsicum annuum L.) fruits, in a genetically controlled scenario, enormous metabolic changes occur that affect the physiology of most cell compartments.
Marta Rodríguez-Ruiz   +6 more
doaj   +1 more source

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