Results 71 to 80 of about 13,323 (173)

Design and radiosynthesis of class-IIa HDAC inhibitor with high molar activity via repositioning the 18F-radiolabel

Scientific Reports
The design and radiosynthesis of [18F]NT376, a high potency inhibitor of class-IIa histone deacetylases (HDAC) is reported. We utilized a three-step radiochemical approach that led to the radiosynthesis of [18F]NT376 in a good radiochemical yield, (17.0 ±
Sulan Xu, Chun-Han Huang, Christopher Eyermann, Georgios V. Georgakis, Nashaat Turkman   +4 more
doaj   +1 more source

Development and Validation of a GMP-Compliant High-Pressure Liquid Chromatography Method for the Determination of the Chemical and Radiochemical Purity of [¹⁸F]PSMA-1007, a PET Tracer for the Imaging of Prostate Cancer. [PDF]

Pharmaceuticals (Basel), 2021
Katzschmann I, Marx H, Kopka K, Hennrich U.   +3 more
europepmc   +1 more source

Synthesis and Preliminary Biological Evaluation of 68Ga-labeled GIPR Targeting Probe

Journal of Isotopes
Glucose-dependent insulinotropic polypeptide receptor (GIPR) is one of the important targets of neuroendocrine tumors (NETs). In this study，a novel GIPR targeting probe 68Ga-DOTA-GIP(1-30)-F-02 was constructed through the module for automatic labeling ...
Pengjun ZHANG, Jiang WU, Bo LUO, Wenyu WU, Feng WANG   +4 more
doaj   +1 more source

PURITY OF RADIOCHEMICALS

Journal of Lipid Research, 1966
openaire   +3 more sources

Fundamental concepts of radiopharmaceuticals quality controls

Pharmaceutical and Biomedical Research, 2018
Quality control (QC) procedures should always be performed following radiopharmaceutical preparation and prior to patient administration. The main aim of QC is to ensure optimal radiopharmaceutical product properties except for some short half-life ...
Sajjad Molavipordanjani, Seyed Jalal Hosseinimehr   +1 more
doaj  

A comparative assessment of radiochemical purity and yield of [¹⁸F]PSMA-1007 production using two different automated synthesis platforms: a head-to-head comparison. [PDF]

EJNMMI Radiopharm Chem
Cossandi M, Statuto M, Migliorati E, Viganò GL, Spiazzi L, Rodella C, Bellini P, Rinaldi R, Camoni L, Dondi F, Biasiotto G, Bertagna F.   +11 more
europepmc   +1 more source

Preparation of Zirconium-89 Solutions for Radiopharmaceutical Purposes: Interrelation Between Formulation, Radiochemical Purity, Stability and Biodistribution. [PDF]

Molecules, 2019
Larenkov A, Bubenschikov V, Makichyan A, Zhukova M, Krasnoperova A, Kodina G.   +5 more
europepmc   +1 more source

Optimization of radiochemical purity assessment for [⁶⁸Ga]Ga-EDOTREOTIDE (Somakit-TOC^®): a shortened r-TLC method for improved PET radiopharmaceutical workflow. [PDF]

EJNMMI Radiopharm Chem
Deschavannes A, Terashi K, Piquemal M, Rioufol C, Clotagatide A.   +4 more
europepmc   +1 more source

[Radiochemical purity and stability of Tc-99m-pyrophosphate].

Medicinski pregled, 2001
In vitro stability of 99mTc-radiopharmaceuticals is an important parameter of quality. In the paper the shelf-life of the bone-seeking radiopharmaceutical 99mTc(Sn)-pyrophosphate was examined under different experimental conditions.The solution of pyrophosphate was prepared and dispensed into 2-ml fractions which were kept at-20 degrees C. In different
openaire   +1 more source

Increasing Analytical Quality by Designing a Thin-Layer Chromatography Scanner Method for the Determination of the Radiochemical Purity of Radiopharmaceutical Sodium Iodide ¹³¹I Oral Solution. [PDF]

Molecules
Vasquez-Huaman M, Castro-Luna A, Ramos-Cevallos NJ, Ramos-Perfecto D, Alcarraz-Curi M, Segura-Vasquez J, Cáceres-Antaurco D.   +6 more
europepmc   +1 more source