Results 111 to 120 of about 3,410 (215)

Rapid, efficient, and economical synthesis of PET tracers in a droplet microreactor: application to O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET). [PDF]

, 2019
BackgroundConventional scale production of small batches of PET tracers (e.g. for preclinical imaging) is an inefficient use of resources. Using O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET), we demonstrate that simple microvolume radiosynthesis ...
Chen, Bao Ying, Clark, Peter M, Fong, Kelly Mun-Ming, Lisova, Ksenia, van Dam, R Michael, Wang, Jia   +5 more
core   +1 more source

Intestinal absorption of glucose in mice as determined by positron emission tomography. [PDF]

, 2018
KEY POINTS:The goal was to determine the importance of the sodium-glucose cotransporter SGLT1 and the glucose uniporter GLUT2 in intestinal glucose absorption during oral glucose tolerance tests (OGTTs) in mice.
Bindslev, Casteleyn, Chow, Debnam, Gallo, Ghezzi, Ghezzi, Gorboulev, Grundy, Guillam, Hediger, Holst, Hummel, James, Kayano, Kellett, Kellett, Kreissl, Kuhre, Loening, Madunic, Mudie, Powell, Rizza, Roder, Sala-Rabanal, Santer, Schmitt, Stumpel, Suckow, Thorens, Thorens, Wong, Wright, Wright, Yamashita, Yu, Yu   +37 more
core   +1 more source

Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([18F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression

EJNMMI Radiopharmacy and Chemistry, 2018
Background Several P-glycoprotein (P-gp) substrate tracers are available to assess P-gp function in vivo, but attempts to develop a tracer for measuring expression levels of P-gp have not been successful. Recently, (Z)-2-(5-fluoro-2-oxoindolin-3-ylidene)-
Joost Verbeek, Jonas Eriksson, Stina Syvänen, Marc Huisman, Robert C. Schuit, Carla F. M. Molthoff, Rob A. Voskuyl, Elizabeth C. de Lange, Adriaan A. Lammertsma, Albert D. Windhorst   +9 more
doaj   +1 more source

Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics [PDF]

, 2014
Benjamin H. Rotstein, Nickeisha A. Stephenson, Neil Vasdev, Steven H. Liang   +3 more
openalex   +1 more source

Direct arene C-H fluorination with 18F- via organic photoredox catalysis [PDF]

, 2019
Positron emission tomography (PET) plays key roles in drug discovery and development, as well as medical imaging. However, there is a dearth of efficient and simple radiolabeling methods for aromatic C-H bonds, which limits advancements in PET ...
Chen, Wei, Giglio, Benjamin, Huang, Zeng, Li, Zibo, Nicewicz, David A, Tay, Nicholas E S, Wang, Hui, Wang, Mengzhe, Wu, Zhanhong   +8 more
core   +2 more sources

Radiochemistry with {Al18F}2+: Current status and optimization perspectives for efficient radiofluorination by complexation

Coordination chemistry reviews, 2023
S. Schmitt, E. Moreau
semanticscholar   +1 more source

Cover Feature: Electrochemical Flash Fluorination and Radiofluorination (ChemElectroChem 22/2018) [PDF]

, 2018
Mehrdad Balandeh, Alejandra Ríos, Nathanael Allison, Daniela Shirazi, Adrian Gomez, Laura Rambaran, Travis Holloway, Saman Sadeghi   +7 more
openalex   +1 more source

Synthese und trägerarme Radiofluorierung von A2A-Adenosin-Rezeptorliganden für die Positronen-Emissions-Tomographie [PDF]

, 2017
The A$_{2A}$ adenosine receptor (A$_{2A}$AR) localized in the brain has important roles in the regulationof glutamate and dopamine release. In several brain disorders like Parkinson`s disease theexpression profile of A$_{2A}$AR is altered which can be ...
Skraban, Marcel Alexander René
core  

Synthesis of ¹⁸F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination

, 2020
Young‐Do Kwon, Min Ho Jeon, Nam Kyu Park, Jeong Kon Seo, Jeongmin Son, Young Hoon Ryu, Sung You Hong, Joong‐Hyun Chun   +7 more
openalex   +2 more sources

Arene radiofluorination enabled by photoredox-mediated halide interconversion

, 2021
Wei Chen, Hui Wang, Nicholas E. S. Tay, Vincent A. Pistritto, Kang-Po Li, Tao Zhang, Zhanhong Wu, David A. Nicewicz, zi-bo Li   +8 more
openalex   +1 more source