Results 161 to 170 of about 2,508 (203)

Iron-catalyzed three-component amino(radio)fluorination of alkenes to unprotected β-(radio)fluoroamines. [PDF]

Nat Commun
Li Y, Zhou Y, Bortolus MR, Zhang X, Wang Z, Liu D, Le H, Esezobor OZ, Ni J, Zhang Q, Vasdev N, Cheng GJ, Zheng C, Fu J.   +13 more
europepmc   +1 more source

Phosphonate-Based Aza-Macrocycle Ligands for Low-Temperature, Stable Chelation of Medicinally Relevant Rare Earth Radiometals and Radiofluorination. [PDF]

J Am Chem Soc
Whetter JN, Śmiłowicz D, Becker KV, Aluicio-Sarduy E, Kelderman CAA, Koller AJ, Glaser OM, Marlin A, Ahn SH, Kretowicz MN, Engle JW, Boros E.   +11 more
europepmc   +1 more source

SYNTHESES OF PRECURSORS TO FLUORINE-18 LABELED PET IMAGING AGENTS [PDF]

, 2014
Boling, Lindsay B
core   +1 more source

Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA. [PDF]

EJNMMI Radiopharm Chem
Lechi F, Eriksson J, Odell LR, Wegrzyniak O, Löfblom J, Frejd FY, Zhang B, Eriksson O.   +7 more
europepmc   +1 more source

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Recent Advances in Photo‐mediated Radiofluorination

Chemistry - an Asian Journal, 2021
AbstractCarbon‐fluorine bond formations have received a lot of attention because organofluorine compounds are widely used in pharmaceutical, agricultural, and materials science applications. In particular, the incorporation of fluorine‐18, which is a commonly used radioisotope for radiopharmaceuticals for positron emission tomography (PET), a molecular
Hee-Kwon Kim
exaly   +3 more sources

Electrochemical Flash Fluorination and Radiofluorination [PDF]

ChemElectroChem, 2018
AbstractA new method for rapid late‐stage fluorination using the cation pool technique is presented. Fluorination and no‐carrier‐added radiofluorination of methyl (phenylthio) acetate, methyl 2‐(methylthio) acetate, and methyl 2‐(ethylthio) acetate were performed.
saman sadeghi, Travis Holloway
exaly   +3 more sources

Electrochemical Radiofluorination of Small Molecules: New Advances

Chemical Record, 2021
AbstractThe development of new 18F‐based radiopharmaceuticals constantly demands innovations in the search for new radiofluorination methods. [18F]fluoride is the simplest and most convenient chemical form of the isotope for the synthesis of 18F‐based radiopharmaceuticals.
Sam Sadeghi
exaly   +3 more sources

Hypervalent aryliodine compounds as precursors for radiofluorination

Journal of Labelled Compounds and Radiopharmaceuticals, 2018
Over the last 2 decades or so, hypervalent iodine compounds, such as diaryliodonium salts and aryliodonium ylides, have emerged as useful precursors for labeling homoarenes and heteroarenes with no‐carrier‐added cyclotron‐produced [18F]fluoride ion (t1/2 = 109.8 min).
Victor W Pike
exaly   +3 more sources

Alcohol‐Enhanced Cu‐Mediated Radiofluorination

Chemistry – A European Journal, 2017
AbstractThe potential of many 18F‐labeled (hetero)aromatics for applications in positron emission tomography remains underexplored because convenient procedures for their radiosynthesis are lacking. Consequently, simple methods to prepare radiofluorinated (hetero)arenes are highly sought after.
Johannes Zischler, Niklas Kolks, Daniel Modemann, Bernd Neumaier, Boris D. Zlatopolskiy   +4 more
openaire   +3 more sources

NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides

Journal of the American Chemical Society, 2020
[18F]-labeled aryl fluorides are widely used as radiotracers for positron emission tomography (PET) imaging. Aryl halides (ArX) are particularly attractive precursors to these radiotracers, as they are readily available, inexpensive, and stable. However, to date, the direct preparation of [18F]-aryl fluorides from aryl halides remains limited to SNAr ...
Liam S Sharninghausen, Allen F Brooks, Wade P Winton   +2 more
exaly   +4 more sources