Results 181 to 190 of about 2,508 (203)

Thermolysis and radiofluorination of diaryliodonium salts derived from anilines

Organic & Biomolecular Chemistry, 2017
Mechanistic and theoretical studies reveal new reactions of Ar2I salts that can interfere with radiolabeling of these substrates.
Ethan J. Linstad, Amy L. Vāvere, Bao Hu, Jayson J. Kempinger, Scott E. Snyder, Stephen G. DiMagno   +5 more
openaire   +2 more sources

Radiofluorination and reductive amination using a microfluidic device

Journal of Labelled Compounds and Radiopharmaceuticals, 2012
A commercial microfluidic device (NanoTek, Advion) was used as a synthesis platform for the preparation of fluorine‐18 labelled tertiary amines in two consecutive steps. Firstly, the nucleophilic radiofluorination of an aromatic aldehyde and secondly, the reductive amination to produce the corresponding amine.
Kenneth Dahl, Magnus Schou, Christer Halldin   +2 more
openaire   +1 more source

No-carrier-added electrochemical nucleophilic radiofluorination of aromatics

Journal of Radioanalytical and Nuclear Chemistry, 2014
Direct nucleophilic radiosynthesis of di-tert-butyl-(4-[18F]fluoro-1,2-phenylene)-dicarbonate was conducted through no-carrier-added electrochemical reactions. 10 mM of triethylamine acetic acid (Et3N·3HAc) in acetonitrile was used to release [18F]fluoride ion trapped in the quaternary ammonium anion exchange resin.
Qinggang He, Ines Alfeazi, Saman Sadeghi
openaire   +1 more source

Aliphatic Nucleophilic Radiofluorination

Current Radiopharmaceuticalse, 2010
Dirk Roeda, Frederic Dolle
openaire   +1 more source

Synthesis of Dibenzothiophenium Salts and Observations in Radiofluorination

Synlett
AbstractWe demonstrate an alternative synthesis of dibenzothiophenium (DBT) salts through a three-step Pd-catalyzed arylation, oxidation, and cyclization sequence. This approach is operationally straightforward and compatible with a variety of common functional groups.
Hui Xiong, Wei Zhang, Juntian Zhang, Adam T. Hoye, Nathaniel C. Lim   +4 more
openaire   +1 more source

Legumain-Triggered Macrocyclization of Radiofluorinated Tracer for Enhanced PET Imaging

Bioconjugate Chemistry
Enhancing the accumulation and retention of small-molecule probes in tumors is an important way to achieve accurate cancer diagnosis and therapy. Enzyme-stimulated macrocyclization of small molecules possesses great potential for enhanced positron emission tomography (PET) imaging of tumors.
Xiaoqing Gao, Qianhui Wang, Xiaofeng Yang, Jing Fang, Huirong Li, Hongjie Xi, Jianguo Lin, Ling Qiu   +7 more
openaire   +2 more sources

Electrochemical no-carrier-added radiofluorination of thioethers

Journal of Fluorine Chemistry, 2022
Nathanael Allison, Mehrdad Balandeh, Travis Holloway, Adrian Gomez, Alejandra Rios, Christopher M. Waldmann, Artem Lebedev, Saman Sadeghi   +7 more
openaire   +1 more source

Copper-Mediated Radiofluorination

Synfacts, 2017
openaire   +1 more source

A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [18F]fluoride: Will [18F]AlF Replace 68Ga for Metal Chelate Labeling?

Molecules, 2019
Cyril Fersing, Ahlem Bouhlel, Philippe Garrigue   +2 more
exaly  

Copper‐Mediated Radiofluorination of Aryl Pinacolboronate Esters: A Straightforward Protocol by Using Pyridinium Sulfonates

European Journal of Organic Chemistry, 2019
Dmitrii Antuganov, Michail Zykov, Vasilii Timofeev   +2 more
exaly