Results 191 to 200 of about 3,410 (215)

Step-by-step optimisation of the radiosynthesis of the brain HDAC6 radioligand [¹⁸F]FSW-100 for clinical applications. [PDF]

EJNMMI Radiopharm Chem
Tago T, Toyohara J.
europepmc   +1 more source

Enhancing the radionuclide theranostic concept through the radiohybrid approach. [PDF]

RSC Med Chem
Krönke T, Kopka K, Mamat C.
europepmc   +1 more source

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Recent Progress on Radiofluorination using Metals: Strategies for Generation of C-18F Bonds

Organic Chemistry Frontiers, 2023
C-F bond formation is an important research topic in organic synthesis because of the wide use of organofluorine compounds in various areas including pharmaceuticals, agricultural applications, and materials science.
Truong Giang Luu, Hee-Kwon Kim
semanticscholar   +1 more source

Preparation of [18F]Alkenyl Fluorides Using No-Carrier-Added [18F]AgF via Silver-Mediated Direct Radiofluorination of Alkynes.

Organic Letters, 2022
We have developed a versatile method for the radiosynthesis of [18F]alkenyl fluorides using no-carrier-added [18F]AgF via the silver-mediated direct radiofluorination of alkynes.
Xinyan Gao, Kehao Gong, Mingwei Wang, Bo Xu, Junbin Han   +4 more
semanticscholar   +1 more source

Synthesis and Application of 1-[18F]Fluoro-4-isothiocyanatobenzene for Radiofluorination of Peptides in Aqueous Medium.

Journal of Organic Chemistry
Conjugation of radiofluorinated prosthetic groups to primary amines of peptides in an aqueous medium is still considerably challenging. Herein, we report a one-pot cascade synthesis of 1-[18F]fluoro-4-isothiocyanatobenzene ([18F]2d), an isothiocyanate ...
S. Gundam, Mathew R Callstrom, Mukesh K. Pandey   +2 more
semanticscholar   +1 more source

Synthesis of Dibenzothiophenium Salts and Observations in Radiofluorination

Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry
We demonstrate an alternative synthesis of dibenzothiophenium (DBT) salts through a three-step Pd-catalyzed arylation, oxidation, and cyclization sequence.
Juntian Zhang, Wei Zhang, Adam T. Hoye, Nathaniel C. Lim, Hui Xiong   +4 more
semanticscholar   +1 more source

Radiofluorination of 2-Arylquinolin-4-yl Oxypropanamide Derivatives for TSPO Imaging in Neuroinflammatory Murine, Nonhuman Primates, and Human Brain Autoradiography with Insensitivity to the rs6971 Polymorphism.

Journal of Medicinal Chemistry
The 18 kDa translocator protein (TSPO) is a critical target for PET imaging of neuroinflammation in central nervous system (CNS) disorders; however, many clinical TSPO PET tracers are limited by sensitivity to rs6971 polymorphism.
Wenqing Ran, Kuan Hu, Weijian Ye, Lingling Zhang, Jiean Chen, Bin Ji, Wakana Mori, Zhiguo Wang, Hao Lu, Achi Haider, Tomoteru Yamasaki, Hongyi Huang, Lin Xie, Qianqian Yang, Shiyu Yuan, Xingkai Wang, Jian Gong, Hao Wang, Steven H. Liang, Jinghao Wang, Rui Wang, Ming-Rong Zhang, Lu Wang   +22 more
semanticscholar   +1 more source

Method for indirect radiofluorination with [^18F]FDG by biorthogonal reaction

The European Physical Journal Special Topics, 2023
G. Simeonova, B. Todorov, Valentina Lyubomirova   +2 more
semanticscholar   +1 more source

Investigation of [18F]Regioisomer Formation in the Radiofluorination of Hypervalent Aryl Iodonium Salts and Ylides

Nuclear Medicine and Biology, 2023
Qunchao Zhao, Jean M Etersque, Shuiyu Lu, Sanjay Telu, Victor Pike   +4 more
semanticscholar   +1 more source

Cu-mediated 18F-radiofluorination of various stannylated FDOPA precursors – what is feasible?

Nuclear Medicine and Biology, 2023
Torsten Knieß, Volha Tuhai, Jörg Zessin, K. Kopka   +3 more
semanticscholar   +1 more source