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Comparative Analysis of Liquid Chromatography-Tandem Mass Spectrometry and Radioimmunoassay in Determining Plasma Aldosterone Concentration and Plasma Renin Activity for Primary Aldosteronism Screening [PDF]

open access: yesEndocrinology and Metabolism
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) accurately measures plasma aldosterone concentration (PAC), but its correlation with radioimmunoassay (RIA), equivalent RIA levels, and optimal cutoff for PAC and aldosterone-to-renin ratio (ARR ...
So Yoon Kwon   +3 more
doaj   +2 more sources

Aldosterone Immunoassay-Specific Cutoff Value for Seated Saline Suppression Test for Diagnosing Primary Aldosteronism [PDF]

open access: yesEndocrinology and Metabolism, 2022
A seated saline loading test (SLT) using liquid chromatography-tandem mass spectrometry (LC-MS/MS) is one of the most accepted confirmatory tests of primary aldosteronism.
So Yoon Kwon   +6 more
doaj   +1 more source

Serum Vitamin D and Uric Acid Levels in Glaucoma Patients: A Comprehensive Investigation [PDF]

open access: yesIndian Journal of Medical Biochemistry, 2023
Objective: Glaucoma is an eye condition characterized by optic nerve damage due to inflammation and oxidative stress, often associated with increased intraocular pressure (IOP). Vitamin D, a fat-soluble vitamin with anti-inflammatory properties, and uric
Pawan Kumar, Isha Malik, Sumit Sachdeva
doaj   +1 more source

Comparison of the Chemiluminescence Immunoassay LIAISON® with the Radioimmunoassay for Aldosterone and Renin Measurement

open access: yesPrague Medical Report, 2021
Determination of renin plasma levels is useful in the diagnosis of hypertension and in the therapeutic follow-up of hypertensive patients. Plasmatic concentration of renin decreases in patients with hypertension due to a primary hyperaldosteronism ...
Jana Uhrová   +3 more
doaj   +1 more source

Comparison of three progesterone quantification methods using blood samples drawn from bitches during the periovulatory phase [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Measuring blood progesterone (P4) concentration has become an essential diagnostic tool in small animal reproductive medicine. Methods enabling precise and rapid on-site measurements are in high demand, especially for the optimization
Hassan A. Hussein   +3 more
doaj   +1 more source

The Enigmatic N-Terminal Domain of Proglucagon; A Historical Perspective

open access: yesFrontiers in Endocrinology, 2021
Enteroglucagon refers to the predominant peptide with glucagon-like immunoreactivity (GLI) that is released by the intestine into the circulation in response to nutrients.
J. Michael Conlon
doaj   +1 more source

Screening for non-classic congenital adrenal hyperplasia in women: New insights using different immunoassays

open access: yesFrontiers in Endocrinology, 2023
ContextThe 250µg-cosyntropin stimulation test (CST) is used to diagnose non-classic congenital adrenal hyperplasia (NCCAH). The current recommendation is to perform CST when follicular 17-hydroxyprogesterone (17OHP) is 6-30 nmol/L, a cutoff derived from ...
Afif Nakhleh   +13 more
doaj   +1 more source

Radioimmunoassay.

open access: yesAnnual Review of Biophysics and Bioengineering, 2020
Radioimmunoassay (RIA) is a technique in which researchers use radioactive isotopes as traceable tags to quantify specific biochemical substances from blood samples.
R. Yalow
semanticscholar   +1 more source

Radioimmunoassay

open access: yesClinical Chemistry, 1973
Abstract Principles of radioimmunoassay are discussed. Methods are outlined for preparing radiolabeled antigenic compounds and characterizing antibodies. The various techniques for separating bound and free antigen are also reviewed. Commercial suppliers of various components needed for radioimmunoassay are listed.
D S, Skelley, L P, Brown, P K, Besch
openaire   +4 more sources

Method Validation and Establishment of Reference Intervals for an Insulin-like Growth Factor-1 Chemiluminescent Immunoassay in Cats

open access: yesVeterinary Sciences, 2023
Previously, radioimmunoassay (RIA) has been the only assay to measure insulin-like growth factor-1 (IGF-1) to diagnose hypersomatotropism (HS). Due to radiation concerns, availability, and the cost of IGF-1 RIA, validation of assays for automated ...
Arne Güssow   +6 more
doaj   +1 more source

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