Results 111 to 120 of about 61,308 (224)
Radioimmunoassay in Gastroenterology
S A, Berson, R S, Yalow
openaire +2 more sources
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Background The aim of this systematic review was to compare the efficacy of methylprednisolone and dexamethasone in severe COVID-19 hospitalized patients.
Jinlv Qin, Guizuo Wang, Dong Han
doaj +1 more source
ABSTRACT Objectives Optimal schedules for longitudinal biomarker sampling are specific to the individual biomarkers and study aims. We present a Bayesian modeling approach for evaluating intraindividual, interindividual, and population‐level biomarker variation in order to optimize precision in parameter estimates and inform biomarker sampling ...
Monica H. Keith +4 more
wiley +1 more source
Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang +8 more
wiley +1 more source
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz +3 more
wiley +1 more source
Schematic illustration of the experimental design for evaluating the protective effects of Oviductus Ranae (OR) against cyclophosphamide (CTX)‐induced premature ovarian failure (POF) in rats. Female Wistar rats were intraperitoneally injected with CTX (100 mg/kg on Day 0, followed by 10 mg/kg daily) for 14–16 days to establish the POF model.
Hongyu Zhao +6 more
wiley +1 more source
ABSTRACT Background In the absence of a gold standard, latent class models can be used to estimate test accuracy from a study comparing results on multiple tests. Fixed‐effect and latent trait models are often used to account for conditional dependencies between tests, mitigating against biased accuracy estimates, but are difficult to implement. Latent
Yasin Okkaoglu +3 more
wiley +1 more source
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A +7 more
wiley +1 more source

