Results 111 to 120 of about 61,308 (224)

Radioimmunoassay in Gastroenterology

open access: yesGastroenterology, 1972
S A, Berson, R S, Yalow
openaire   +2 more sources

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Methylprednisolone versus dexamethasone in hospitalized patients with severe COVID-19: a systematic review and meta-analysis of randomized controlled trials

open access: yesSystematic Reviews
Background The aim of this systematic review was to compare the efficacy of methylprednisolone and dexamethasone in severe COVID-19 hospitalized patients.
Jinlv Qin, Guizuo Wang, Dong Han
doaj   +1 more source

A Bayesian Modeling Approach to Optimize Longitudinal Biomarker Sampling Schedules Using Hormonal Data

open access: yesAmerican Journal of Human Biology, Volume 38, Issue 7, July 2026.
ABSTRACT Objectives Optimal schedules for longitudinal biomarker sampling are specific to the individual biomarkers and study aims. We present a Bayesian modeling approach for evaluating intraindividual, interindividual, and population‐level biomarker variation in order to optimize precision in parameter estimates and inform biomarker sampling ...
Monica H. Keith   +4 more
wiley   +1 more source

Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 7, July 2026.
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang   +8 more
wiley   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

open access: yesDrug Testing and Analysis, Volume 18, Issue 7, Page 862-876, July 2026.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz   +3 more
wiley   +1 more source

Oviductus Ranae as a Functional Food for Ovary Protection: Ameliorating Premature Ovarian Failure and Modulating PI3K/Akt and Apoptosis Pathways in Rats

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic illustration of the experimental design for evaluating the protective effects of Oviductus Ranae (OR) against cyclophosphamide (CTX)‐induced premature ovarian failure (POF) in rats. Female Wistar rats were intraperitoneally injected with CTX (100 mg/kg on Day 0, followed by 10 mg/kg daily) for 14–16 days to establish the POF model.
Hongyu Zhao   +6 more
wiley   +1 more source

Latent Class Log‐Linear Models for Estimating Diagnostic Test Accuracy Without a Gold Standard: A Simulation Study

open access: yesStatistics in Medicine, Volume 45, Issue 15-17, July 2026.
ABSTRACT Background In the absence of a gold standard, latent class models can be used to estimate test accuracy from a study comparing results on multiple tests. Fixed‐effect and latent trait models are often used to account for conditional dependencies between tests, mitigating against biased accuracy estimates, but are difficult to implement. Latent
Yasin Okkaoglu   +3 more
wiley   +1 more source

Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study

open access: yesAndrology, Volume 14, Issue 5, Page 1209-1219, July 2026.
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A   +7 more
wiley   +1 more source

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