Results 131 to 140 of about 129,731 (303)

Downregulation of EPAS1 and EGLN1 mRNA Expression Associated With High‐Altitude Adaptive Genetic Variants in Sherpa Highlanders

open access: yesAnnals of Human Genetics, Volume 90, Issue 3, Page 202-214, May 2026.
ABSTRACT Background and Aims Sherpa highlanders exhibit remarkable tolerance to hypoxia, most likely due to genetic adaptations shaped by natural selection at high altitude. This study examined the roles of endothelial PAS domain protein 1 (EPAS1) and egl‐9 family hypoxia‐inducible factor 1 (EGLN1) in the genetic mechanisms underlying this adaptation ...
Yunden Droma   +5 more
wiley   +1 more source

Methylprednisolone versus dexamethasone in hospitalized patients with severe COVID-19: a systematic review and meta-analysis of randomized controlled trials

open access: yesSystematic Reviews
Background The aim of this systematic review was to compare the efficacy of methylprednisolone and dexamethasone in severe COVID-19 hospitalized patients.
Jinlv Qin, Guizuo Wang, Dong Han
doaj   +1 more source

Studies on radioimmunoassay of metanephrine.

open access: bronze, 1980
Akira Shirahata   +3 more
openalex   +2 more sources

Radioimmunoassay for pregnancy-associated plasma protein A. [PDF]

open access: bronze, 1982
Michael J. Sinosich   +4 more
openalex   +1 more source

Evaluation of a Therapeutic Drug Monitoring Strategy for Adalimumab in Psoriasis: A Prospective Pharmacokinetic‐Pharmacodynamic Study

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Using a real‐world psoriasis cohort, we established the pharmacokinetic‐pharmacodynamic (PKPD) relationship for the biologic therapy adalimumab and evaluated the clinical utility and cost‐effectiveness of a proactive therapeutic drug monitoring (TDM) strategy.
Shan Pan   +38 more
wiley   +1 more source

A novel glucose beta‐hydroxybutyrate combination improves hypoglycaemia recovery and patient‐reported outcomes in type 1 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3590-3597, May 2026.
Abstract Aims Hypoglycaemia remains a major barrier to optimal diabetes management. Current treatments based on simple sugars have limitations, including rapid glucose fluctuations and persistent neuroglycopenic symptoms. We investigated FLO23011, a novel multi‐substrate energy formulation containing glucose and beta‐hydroxybutyrate, as a superior ...
D. Russell‐Jones   +5 more
wiley   +1 more source

Performance of an automated insulin‐glucagon delivery system versus automated insulin delivery system during challenging inpatient conditions. A single‐blind randomised controlled crossover trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3955-3964, May 2026.
Abstract Aims To assess the efficacy and safety of an automated insulin‐glucagon delivery system (AIGD) compared with an automated insulin delivery system (AID). Materials and methods In a 33‐h, randomised, crossover, inpatient study, 13 participants with type 1 diabetes used the DiaCon system in AIGD and AID modes.
Ajenthen G. Ranjan PhD   +7 more
wiley   +1 more source

Problems in automation of serum cortisol radioimmunoassay [PDF]

open access: yes, 1978
Müller, O. A.   +3 more
core   +1 more source

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