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DLL3-targeted immunoPET and radioimmunotherapy ligands. [PDF]
Liang SH.
europepmc +1 more source
Cancer Radioimmunotherapy [PDF]
Targeting of radionuclides with antibodies, or radioimmunotherapy, has been an active field of research spanning nearly 50 years, evolving with advancing technologies in molecular biology and chemistry, and with many important preclinical and clinical studies illustrating the benefits, but also the challenges, which all forms of targeted therapies face.
David M Goldenberg
exaly +4 more sources
Clinical Radioimmunotherapy—The Role of Radiobiology
International audienceConventional external-beam radiation therapy is dedicated to the treatment of localized disease, whereas radioimmunotherapy represents an innovative tool for the treatment of local or diffuse tumors.
Jean-Pierre Pouget +2 more
exaly +2 more sources
Radioimmunotherapy of Pancreatic Ductal Adenocarcinoma: A Review of the Current Status of Literature [PDF]
Pancreatic ductal adenocarcinoma (PDAC) has long been associated with low survival rates. A lack of accurate diagnostic tests and limited treatment options contribute to the poor prognosis of PDAC.
Eva Bezak, Ashleigh Hull
exaly +2 more sources
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Experimental radioimmunotherapy
Medical Physics, 1993Radiolabeled monoclonal antibodies have been used for radioimmunotherapy studies with human tumor spheroids and murine and human tumor xenografts in experimental animals. This paper reviews the work that has been performed in these models with different types of cancer, and highlights those papers that have presented dosimetry estimates and attempts to
D J, Buchsbaum +2 more
openaire +2 more sources
Radioimmunotherapy of Brain Tumor
Neurological Research, 2006Despite years of intensive research, the prognosis of high-grade gliomas (HGG) remains poor, as these tumors are highly resistant to currently available therapies. Therefore, there is a need for the development of new therapeutic strategies, such as the use of monoclonal antibodies (MoAbs) in association with radioisotopes, in order to achieve better ...
Giovanni Paganelli +2 more
exaly +3 more sources
An overview of radioimmunotherapy
Cancer Immunology Immunotherapy, 1991In reviewing the current state of affairs in radioimmunotherapy the paper focuses on the main difficulties thus far encountered and the procedures designed to avoid or circumvent these problems. The long range beta-emitters 90Y and 188Re have replaced 131I as the isotopes currently receiving most attention for use in radioimmunotherapy, and a range of ...
A, Maraveyas, A A, Epenetos
openaire +2 more sources
Radioimmunodetection and Radioimmunotherapy
Cancer Investigation, 1984The development of monoclonal antibodies that recognize tumor-associated antigens has led to significantly greater practical possibilities for producing highly specific radiolabeled antibodies for diagnosis and therapy of human tumors. A number of problems remain before this technique will be ready for routine clinical application however.
S M, Larson +2 more
openaire +2 more sources

