Results 21 to 30 of about 15,914 (251)

Fate of 177Lu-CHX-A”-DTPA-Rituximab: In vitro Evaluation in Raji Cell Line

Journal of Radiation and Cancer Research, 2023
Context: Radioimmunotherapy is an emerging treatment modality for various types of cancers. While immunotherapy using monoclonal antibodies has shown promising results, particularly in hematological malignancies, a significant number of patients develop ...
Saloni Arun Samant, Chandan Kumar, Usha Pandey   +2 more
doaj   +1 more source

Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. [PDF]

, 2014
Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Bonavida, Benjamin, Shvartsur, Anna
core   +2 more sources

Bone marrow recovery and subsequent chemotherapy following radiolabeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody J591 in men with metastatic castration-resistant prostate cancer

Frontiers in Oncology, 2013
Radioimmunotherapy has demonstrated efficacy with acceptable toxicity leading to approval in non-Hodgkin’s lymphoma, but has been slower to develop for the treatment of advanced solid tumors.
Scott T Tagawa, Scott T Tagawa, Naveed Hassan Akhtar, Anastasia eNikolopoulou, Gurveen eKaur, Brian eRobinson, Renee eKahn, Shankar eVallabhajosula, Stanley J Goldsmith, David M Nanus, David M Nanus, Neil H Bander   +11 more
doaj   +1 more source

Current concepts of radioimmonotherapy for lymphoma [PDF]

Vojnosanitetski Pregled, 2015
nema
Mihailović Jasna, Ubavić Milan, Trifunović Jasna   +2 more
doaj   +1 more source

Immunotherapy and Radioimmunotherapy for Desmoplastic Small Round Cell Tumor

Frontiers in Oncology, 2021
Desmoplastic small round cell tumor (DRSCT) is a highly aggressive primitive sarcoma that primarily affects adolescent and young adult males. The 5-year survival rate is 15-30% and few curative treatment options exist.
Madelyn Espinosa-Cotton, Nai-Kong V. Cheung   +1 more
doaj   +1 more source

Pattern of antigen expression in metastases after radioimmunotherapy of a syngeneic rat colon carcinoma utilizing the BR96 antibody

Experimental Hematology & Oncology, 2012
Background Repeated administration of antibody-based therapies such as radioimmunotherapy depends on preserved antigen expression in tumor lesions. The purpose of this study was to evaluate whether the antigen expression in metastases observed after ...
Elgström Erika, Eriksson Sophie E, Ohlsson Tomas G, Tennvall Jan, Nilsson Rune   +4 more
doaj   +1 more source

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics [PDF]

, 2019
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR ...
Beattie, Bradley J., Beattie, Kai A., Elgqvist, Jörgen, Eriksson, Sophie E., Larsson, Erik, Strand, Sven-Erik, Thorek, Daniel L. J., Timmermand, Oskar Vilhelmsson, Tran, Thuy A., Ulmert, David, Örbom, Anders   +10 more
core   +2 more sources

Evaluation of response to fractionated radioimmunotherapy with 90Y-epratuzumab in non-Hodgkin’s lymphoma by 18F-fluorodeoxyglucose positron emission tomography

Haematologica, 2008
Background The study aimed to evaluate FDG-PET imaging for early prediction of response to radioimmunotherapy in patients with non-Hodgkin’s lymphoma.Design and Methods Twenty-seven patients from a large ongoing, multicenter, phase I/II trial of ...
Caroline Bodet-Milin, Françoise Kraeber-Bodéré, Benoît Dupas, Franck Morschhauser, Thomas Gastinne, Steven Le Gouill, Loïc Campion, Jean-Luc Harousseau, William A. Wegener, David M. Goldenberg, Damien Huglo   +10 more
doaj   +1 more source

Synthesis and characterisation of biologically compatible TiO2 nanoparticles [PDF]

, 2011
Peer reviewedPublisher ...
Cheyne, Richard William, McLaughlin, Abbie, Smith, Timothy Andrew Davies, Trembleau, Laurent Alain Claude   +3 more
core   +2 more sources

Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices [PDF]

, 2013
Objective The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment.
Burcombe R, Cai L, Eriksson D, Eriksson D, Fernberg JO, Hattersley SM, Hattersley SM, Ianzini F, Jemal A, Kamotani Y, Kroemer G, Lee P, Ma H, Mamouni J, Mansilla S, Mauk MG, Mirzaie-Joniani H, Mulhall HJ, Nevill JT, Parkin DM, Reddy AC, Remmerbach TW, Skoda C, Ts’ao C, Weigum SE, Withrow KP, Young EW, Ziober BL   +27 more
core   +2 more sources