Results 21 to 30 of about 13,452 (195)

Radioimmunotherapy: A novel treatment of non-Hodgkin lymphoma [PDF]

open access: yesArchive of Oncology, 2010
90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab (Bexxar) are current choices for radioimmunotherapy (RIT) of patients with follicular rituximab-relapsed or refractory CD20+ follicular B-cell NHL.
Petrović Tomislav, Mihailović Jasna
doaj   +1 more source

Perspectives on metals-based radioimmunotherapy (RIT): moving forward

open access: yesTheranostics, 2021
Radioimmunotherapy (RIT) is FDA-approved for the clinical management of liquid malignancies, however, its use for solid malignancies remains a challenge.
J. White   +2 more
semanticscholar   +1 more source

Fate of 177Lu-CHX-A”-DTPA-Rituximab: In vitro Evaluation in Raji Cell Line

open access: yesJournal of Radiation and Cancer Research, 2023
Context: Radioimmunotherapy is an emerging treatment modality for various types of cancers. While immunotherapy using monoclonal antibodies has shown promising results, particularly in hematological malignancies, a significant number of patients develop ...
Saloni Arun Samant   +2 more
doaj   +1 more source

Current concepts of 131I therapy in oncology: Indications, methods and follow up [PDF]

open access: yesArchive of Oncology, 2006
Radioiodine in various forms (as sodium iodide and as the iodinated compounds MIBG, LIPIODOL, et al.) has been used as a therapeutic agent in oncology. Differentiated thyroid carcinoma (DTC) has been successfully treated by 131I therapy.
Mihailović Jasna
doaj   +1 more source

Bone marrow recovery and subsequent chemotherapy following radiolabeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody J591 in men with metastatic castration-resistant prostate cancer

open access: yesFrontiers in Oncology, 2013
Radioimmunotherapy has demonstrated efficacy with acceptable toxicity leading to approval in non-Hodgkin’s lymphoma, but has been slower to develop for the treatment of advanced solid tumors.
Scott T Tagawa   +11 more
doaj   +1 more source

Radioimmunotherapy in Oncology: Overview of the Last Decade Clinical Trials

open access: yesCancers, 2021
Simple Summary Monoclonal antibody-bearing radionuclides have been under clinical investigation over the last two decades for their use in theranostic (diagnostic and therapeutic) applications in cancer.
Aurélie Rondon, J. Rouanet, F. Degoul
semanticscholar   +1 more source

Pattern of antigen expression in metastases after radioimmunotherapy of a syngeneic rat colon carcinoma utilizing the BR96 antibody

open access: yesExperimental Hematology & Oncology, 2012
Background Repeated administration of antibody-based therapies such as radioimmunotherapy depends on preserved antigen expression in tumor lesions. The purpose of this study was to evaluate whether the antigen expression in metastases observed after ...
Elgström Erika   +4 more
doaj   +1 more source

Narrative review of emerging roles for AKT-mTOR signaling in cancer radioimmunotherapy

open access: yesAnnals of Translational Medicine, 2021
Objective To summarize the roles of AKT-mTOR signaling in the regulation of the DNA damage response and PD-L1 expression in cancer cells, and propose a novel strategy of targeting AKT-mTOR signaling in combination with radioimmunotherapy in the era of ...
Changxian Shen   +6 more
semanticscholar   +1 more source

Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models

open access: yesPharmaceuticals, 2021
Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant improvements in the last two decades, and novel effective treatments are needed.
Jaline Broqueza   +8 more
doaj   +1 more source

Evaluation of response to fractionated radioimmunotherapy with 90Y-epratuzumab in non-Hodgkin’s lymphoma by 18F-fluorodeoxyglucose positron emission tomography

open access: yesHaematologica, 2008
Background The study aimed to evaluate FDG-PET imaging for early prediction of response to radioimmunotherapy in patients with non-Hodgkin’s lymphoma.Design and Methods Twenty-seven patients from a large ongoing, multicenter, phase I/II trial of ...
Caroline Bodet-Milin   +10 more
doaj   +1 more source

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