Results 71 to 80 of about 12,381 (205)
Assessment of pTERT subtypes of glioblastoma by quantitative FLAIR analysis based on fusing MRI images, Participants, Methods, Results, Glioblastoma patients, Segmented to 3 subregions Investigated the significant metrics of subregions and other clinical‐imaging factors Prediction models of pTERT Tested in validation cohorts pTERTm, pTERTw, Conclusion:
Bocong Gao +3 more
wiley +1 more source
Radioimmunotherapy of Lymphoma
Radiolabeled monoclonal antibodies for the treatment of follicular low-grade non-Hodgkin’s lymphoma have been available for several years in the United States and more recently throughout Europe. Since their introduction to treatment of refractory or relapsed patients, they have been evaluated for efficacy earlier in the course of the disease including
openaire +3 more sources
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
Jing Wang,1 Firas Baidoun,2 Han W Tun,2 Muhamad Alhaj Moustafa2 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL, 32224, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic Florida, Jacksonville, FL, 32224 ...
Wang J +3 more
doaj
Radiolabeled Antibody Fragment for Preparation of (177Lu-DOTA)m-PAMAM G3.0-F(ab\u27)2 Trastuzumab as a Radiopharmaceutical for Cancer Therapy [PDF]
Several radiolabeled monoclonal antibodies (mAbs) have been used as radioimmunotherapy (RIT) agents for cancer therapy. The use of mAbs as RIT agents is due to their ability to carry effectors, in the form of radionuclides which emit alpha (α) particles,
Haryuni, R. D. (R) +3 more
core +3 more sources
Radioimmunotherapy of Infectious Diseases [PDF]
The need for novel approaches to treat infectious diseases is obvious and urgent. This situation has renewed interest in the use of monoclonal antibodies (mAbs) to treat infectious diseases. During the last 5 years, radioimmunotherapy (RIT), a modality developed for cancer treatment, has been successfully adapted for the treatment of experimental ...
Ekaterina, Dadachova, Arturo, Casadevall
openaire +2 more sources
Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li +11 more
wiley +1 more source
Radioimmunotherapy Dosimetry—A Review [PDF]
Results from therapeutic trials in systemic radiation therapy with radiolabelled monoclonal antibodies are difficult to compare, because of lack of accurate dosimetry. This applies macroscopically as well as microscopically for both tumours and normal tissues.
S E, Strand +3 more
openaire +2 more sources
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh +7 more
wiley +1 more source
Background Pancreatic ductal adenocarcinoma (PDAC) accounts for >90% of pancreatic malignancies, and has median survival of
Rubin Jiao +9 more
doaj +1 more source

