Results 81 to 90 of about 12,381 (205)

In vitro characterization of 177Lu-radiolabelled chimeric anti-CD20 monoclonal antibody and a preliminary dosimetry study [PDF]

, 2018
Purpose: 131I- and 90Y-labelled anti-CD20 antibodies have been shown to be effective in the treatment of low-grade, B-cell non-Hodgkin's lymphoma (NHL).
Chen, Jianhua, Fani, Melpomeni, Forrer, Flavio, Lohri, Andreas, Maecke, Helmut, Moldenhauer, Gerhard, Müller-Brand, Jan, Powell, Pia   +7 more
core  

Silencing E3 Ubiqutin ligase ITCH as a potential therapy to enhance chemotherapy efficacy in p53 mutant neuroblastoma cells [PDF]

, 2020
P53 mutations are responsible for drug-resistance of tumour cells which impacts on the efficacy of treatment. Alternative tumour suppressor pathways need to be explored to treat p53- deficient tumours.
Hart, Stephen L, Meng, Jinhong, Tagalakis, Aristides D   +2 more
core   +2 more sources

Newly Identified Transcriptomic Biomarkers and Gene Signature of Pathological Complete Response to Induction Chemoimmunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

MedComm, Volume 7, Issue 1, January 2026.
Scheme and pathological characteristics of the CheckRad‐CD8 trial cohort used for the transcriptome analyses. (A) Flow diagram depicting the patient cohort and study scheme as the basis for whole transcriptome profiling of samples from locally advanced HNSCC patients treated with induction chemoimmunotherapy (iCIT).
Jian‐Guo Zhou, Markus Eckstein, Haitao Wang, Tianjun Lan, Benjamin Frey, Xin Li, Xiaofan Lu, Gunther Klautke, Thomas Illmer, Maximilian Fleischmann, Simon Laban, Matthias G. Hautmann, Bálint Tamaskovics, Thomas B. Brunner, Arndt Hartmann, Rainer Fietkau, Hu Ma, Antoniu‐Oreste Gostian, Heinrich Iro, Markus Hecht, Udo S. Gaipl   +20 more
wiley   +1 more source

Review of (90)Y-ibritumomab tiuxetan as first-line consolidation radio-immunotherapy for B-cell follicular non-Hodgkin’s lymphoma

Cancer Management and Research, 2009
Christos EmmanouilidesDepartment of Medical Oncology, Interbalkan Hospital, Thessaloniki, GreeceAbstract: Several studies have indicated that radioimmunotherapy is an effective and clinically relevant complementary therapeutic approach for patients with ...
Christos Emmanouilides
doaj  

HASH(0x563d440a43c8) [PDF]

, 2009
HASH(0x563d44119a80)HASH ...
Nachtnebel, A.
core  

Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]

, 2018
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar, Detering, Lisa, Liu, Yongjian, Luehmann, Hannah, Pang, Bo, Sultan, Deborah, Xia, Younan, Yang, Miaoxin, Zhao, Yongfeng   +8 more
core   +2 more sources

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

Rare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu, Ding‐Hu Zhang, Chuan Hu, Yi‐Nan Ding, Kun Chen, Yi Jiang, Jun Luo, Fei Cao, Wei‐Yuan Hao, Bin‐Yan Zhong, Jie Lin, Dong Xu, Jia‐Ping Zheng   +12 more
wiley   +1 more source

Toxicological Studies of 212Pb Intravenously or Intraperitoneally Injected into Mice for a Phase 1 Trial

Pharmaceuticals, 2015
Faced with the novelty of a 212Pb-labeled monoclonal antibody (mAb) for clinical translation, concerns were expressed by the Food and Drug Administration (FDA) regarding 212Pb prematurely released from the mAb-chelate conjugate.
Diane E. Milenic, Alfredo A. Molinolo, María S. Solivella, Eileen Banaga, Julien Torgue, Sarah Besnainou, Martin W. Brechbiel, Kwamena E. Baidoo   +7 more
doaj   +1 more source

Targeted therapy in nuclear medicine—current status and future prospects [PDF]

, 2017
In recent years, a number of new developments in targeted therapies using radiolabeled compounds have emerged. New developments and insights in radioiodine treatment of thyroid cancer, treatment of lymphoma and solid tumors with radiolabeled monoclonal ...
Bodei, L., Brans, B., Giammarile, F., Luster, M., Maecke, H. R., Oyen, W. J. G., Tennvall, J.   +6 more
core  

Differentiation of irradiation and cetuximab induced skin reactions in patients with locally advanced head and neck cancer undergoing radioimmunotherapy: the HICARE protocol (Head and neck cancer: ImmunoChemo and Radiotherapy with Erbitux) – a multicenter phase IV trial [PDF]

, 2013
BACKGROUND: In order to improve the clinical outcome of patients with locally advanced squamous cell carcinoma of the head and neck (LASCCHN) not being capable to receive platinum-based chemoradiation, radiotherapy can be intensified by addition of ...
A Abdollahi, E Boller, G Habl, J Debus, JC Hassel, K Potthoff, M Indorf, MF Haefner   +7 more
core   +1 more source