Results 171 to 180 of about 88,244 (379)

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs [PDF]

open access: bronze, 2000
Matthew Bogyo   +4 more
openalex   +1 more source

Expression of a Bacterial Trehalose 6‐Phosphate Synthase Gene otsA in Camelina sativa Seeds Promotes the Channelling of Carbon Towards Oil Accumulation

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Improving seed oil yield is essential for developing Camelina sativa as a sustainable biofuel crop. Fatty acid synthesis depends on the production of acetyl‐CoA from photosynthetically derived sugars. Trehalose 6‐phosphate (T6P), a proxy for sucrose availability, can link sugar status to plant growth and development. Synthesised by trehalose 6‐
Saroj Kumar Sah   +7 more
wiley   +1 more source

Drought‐Induced Abscisic Acid Accumulation in Soybean Roots Depends on NCED Gene Expression More Than Shoot‐to‐Root ABA Transport

open access: yesPlant, Cell &Environment, EarlyView.
Abstract Abscisic acid (ABA) is a key phytohormone in plant responses to water deficit. Although there is extensive evidence that roots can synthesise ABA, recent findings suggest that local synthesis in response to dehydration contributes little to the root ABA pool compared to shoot‐sourced ABA.
Jaime Puértolas   +4 more
wiley   +1 more source

Fluorine‐18 Fluorodeoxyglucose‐Positron Emission Tomography/Computed Tomography for Detection of Lymph Node Metastasis in Canine Mast Cell Tumour

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Lymph node (LN) metastasis has been associated with shorter survival times in dogs with mast cell tumour (MCT), and treatment of metastatic LN with lymphadenectomy or irradiation has been demonstrated to improve outcomes. Identification of metastatic LN in dogs with MCT is therefore of both prognostic and therapeutic significance.
Alison C. Williams   +5 more
wiley   +1 more source

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa   +4 more
wiley   +1 more source

Tunable and noncytotoxic PET/SPECT-MRI multimodality imaging probes using colloidally stable ligand-free superparamagnetic iron oxide nanoparticles

open access: yesInternational Journal of Nanomedicine, 2017
TH Nguyen Pham,1 Nigel A Lengkeek,2 Ivan Greguric,2 Byung J Kim,1 Paul A Pellegrini,2 Stephanie A Bickley,3 Marcel R Tanudji,3 Stephen K Jones,3 Brian S Hawkett,1 Binh TT Pham1 1Key Centre for Polymers and Colloids, School of Chemistry, University of ...
Pham THN   +9 more
doaj  

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

open access: yesDrug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal   +4 more
wiley   +1 more source

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