Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs [PDF]
, 2000 Matthew Bogyo +4 more
openalex +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT We developed a comprehensive, mechanistic model of human copper metabolism to support biomarker qualification for VTX‐801, an adeno‐associated vector‐based gene therapy which is being developed to restore the mutated ATP7B copper transporter gene in Wilson disease (WD). The model integrates physiological copper kinetics with pathophysiological
Andreas Lindauer +3 more
wiley +1 more source
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Small, EarlyView.Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
Small, EarlyView.Collagen microgels (CMGs) incubated with cells self‐assemble into CMG‐based cellular microtissues (CCMs), enhancing cell adhesion and upregulating IL‐8 expression. A combinatorial strategy that integrates the CMG platform with IL‐8 overexpression promotes cell proliferation, migration, angiogenesis, and survival, thereby accelerating diabetic wound ...
Haeun Chung +3 more
wiley +1 more source
Scanning for Tumours with Radiolabeled Antibodies: A Review [PDF]
, 1983 P W Dykes +2 more
openalex +1 more source
Hydrogel Microspheres for Biomedical Applications
Small Science, EarlyView.Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang +11 more
wiley +1 more source
Noninvasive Detection of Plaque Instability with Use of Radiolabeled Annexin A5 in Patients with Carotid-Artery Atherosclerosis [PDF]
, 2004 Bas Kietselaer +6 more
openalex +1 more source
Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach
The Chemical Record, EarlyView.This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos +3 more
wiley +1 more source
A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator [PDF]
Aitor Herraiz +17 more
openalex +3 more sources
Aerosol-synthesized siliceous nanoparticles: Impact of morphology and functionalization on biodistribution [PDF]
, 2018 Bandara, Nilantha +7 more
core +2 more sources