Results 181 to 190 of about 88,244 (379)
Aerosol-synthesized siliceous nanoparticles: Impact of morphology and functionalization on biodistribution [PDF]
Bandara, Nilantha +7 more
core +2 more sources
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source
Microbubble‐enabled focused ultrasound (MB‐FUS) has revolutionized nano and molecular drug delivery capabilities. Yet, the absence of longitudinal, systematic, quantitative studies of microbubble shell pharmacokinetics hinders progress within the MB‐FUS ...
Maneesha A. Rajora +9 more
doaj +1 more source
Differences in Src phosphorylation of PSD‐93 and PSD‐95 drive differences in scaffolding activity
Abstract Scaffold proteins contain multiple binding modules that allow for co‐localization of proteins that lack a direct interaction. Evolution resulted in different combinations of binding modules that rewired existing signal transduction pathways.
Frank A. Mindlin +3 more
wiley +1 more source
Diazirines are three‐membered, nitrogen‐containing heterocycles that decompose under light or heat to generate carbenes. For the past two decades, they have served mainly as minimally invasive tags in photoaffinity labeling (PAL). More recently, their value as versatile carbene precursors has been recognized.
Dominik Schnalzer +4 more
wiley +2 more sources
Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology [PDF]
Martha Sahylí Ortega Pijeira +12 more
openalex +1 more source
Deceptive beauty of non‐natural structures
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich +1 more
wiley +1 more source
Structural Investigations, Cellular Imaging, and Radiolabeling of Neutral, Polycationic, and Polyanionic Functional Metalloporphyrin Conjugates [PDF]
Valeria Ciaffaglione +13 more
openalex +1 more source

