Results 181 to 190 of about 87,481 (331)
Synthesis, modification, characterization, radiolabeling and in vivo behavior of carboxylated nanographene oxide sheets as a tumor imaging agent [PDF]
, 2021 Mohammed F. Elsabagh +4 more
openalex +1 more source
VIEW, EarlyView.A CD47‐targeted dual‐modal imaging probe combining positron emission tomography and second near‐infrared fluorescence enables precise preoperative tumor localization and intraoperative guidance for complete resection of breast cancer lesions, including metastases, offering a promising strategy to enhance surgical accuracy and improve clinical outcomes.
Jun Li +9 more
wiley +1 more source
PSMA PET‐directed radiotherapy for prostate cancer: From precision planning to future innovations
VIEW, EarlyView.Prostate‐specific membrane antigen (PSMA) positron emission tomography (PET) imaging enables highly sensitive detection of prostate cancer recurrence and precise lesion mapping. This review summarizes current evidence and emerging applications of PSMA PET in radiotherapy, including diagnostic staging, target delineation, adaptive planning, and outcome ...
Wenpeng Huang +7 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and purpose Patients with amyotrophic lateral sclerosis (ALS) are prescribed many medications for symptomatic relief. However, how potential alterations to the blood–brain barrier (BBB) affect the brain exposure of drugs in ALS remains under‐investigated. Experimental approach We used high‐dimensional proteomic analysis, cellular metabolism,
Yijun Pan +10 more
wiley +1 more source
Cancer Science, EarlyView.This study demonstrates that combining liposomal Rhenium‐188 (Lipo‐Re188) with macrophage depletion and anti–PD‐L1 therapy enhances therapeutic efficacy against lung metastatic colon cancer. The triple therapy promotes B cell infiltration, restores T cell function, and suppresses MDSC, creating a tumor‐suppressive immune microenvironment.
Shin‐Yi Liu +3 more
wiley +1 more source
Correction to: Synthesis and Application of a Long-Circulating Radiolabeled Peptide for Targeting of Osteosarcoma [PDF]
, 2021 Yesen Li +4 more
openalex +1 more source
Cancer Science, EarlyView.Radionuclide therapy using PD‐K(225Ac‐DOTA)‐RGD in BxPC‐3‐bearing mice. PD‐K(225Ac‐DOTA)‐RGD successfully suppressed tumor growth. ABSTRACT Improved peptide pharmacokinetics are needed to enhance the therapeutic effects of peptide‐based radionuclide therapy.
Mitsuyoshi Yoshimoto +5 more
wiley +1 more source
Synthetic trap‐peptides identify a TOM complex phosphatase – PP2A dephosphorylates Tom6
The FEBS Journal, EarlyView.Synthetic trap‐peptides facilitate the identification of complete holoenzymes that bind to the target sequence remarkably close to the phosphorylation site. PP4 bound to, but did not dephosphorylate, the peptide substrate taken from yeast Tom6 pSer16, showing that proximity alone does not induce phosphatase activity.
Laura Scheinost +7 more
wiley +1 more source
Phase I Trial of Well-Differentiated Neuroendocrine Tumors (NETs) with Radiolabeled Somatostatin Antagonist 177Lu-Satoreotide Tetraxetan [PDF]
, 2019 Diane Reidy‐Lagunes +11 more
openalex +1 more source