Results 101 to 110 of about 2,283,209 (217)

Binding of imipramine to phospholipid bilayers using radioligand binding assay.

General physiology and biophysics, 2005
Binding of the tricyclic antidepressant imipramine (IMI) to neutral and negatively charged lipid membranes was investigated using a radioligand binding assay combined with centrifugation or filtration. Lipid bilayers were composed of brain phosphatidylcholine (PC) and phosphatidylserine (PS).
Z, Fisar, K, Fuksová, M, Velenovská
openaire   +1 more source

Dopamine D2-like receptors on human peripheral blood lymphocytes: a radioligand binding assay and immunocytochemical study

, 1999
1. Peripheral blood lymphocytes express dopamine D1-like and D2-like receptors which were investigated using radioligand binding assay and molecular biology techniques.
AMENTA, Francesco, E. BRONZETTI, L. FELICI, A. RICCI, TAYEBATI, Seyed Khosrow   +4 more
core  

LABELING OF DOPAMINE D3 AND D4 RECEPTOR SUBTYPES IN HUMAN PERIPHERAL BLOOD LYMPHOCYTES WITH [3H]7-OH-DPAT: A COMBINED RADIOLIGAND BINDING ASSAY AND IMMUNOCHEMICAL STUDY

, 1998
Molecular biology studies have demonstrated that human peripheral blood lymphocytes express dopamine D2-like receptors belonging to the D3 and D4 receptor subtypes, whereas the characterization of these receptors using radioligand binding assay ...
GRECO S., AMENTA, Francesco, FELICI L., RICCI A., BRONZETTI E.   +4 more
core   +1 more source

Labelling of dopamine D3 and D4 receptor subtypes in human peripheral blood lymphocytes with [3H]7-OH-DPAT: a combined radioligand binding assay and immunochemical study.

, 1998
Molecular biology studies have demonstrated that human peripheral blood lymphocytes express dopamine D2-like receptors belonging to the D3 and D4 receptor subtypes, whereas the characterization of these receptors using radioligand binding assay ...
AMENTA, Francesco
core   +1 more source

In vitro screening of major neurotransmitter systems possibly involved in the mechanism of action of antibodies to S100 protein in released-active form

Neuropsychiatric Disease and Treatment, 2015
Evgeniy A Gorbunov, Irina A Ertuzun, Evgeniya V Kachaeva, Sergey A Tarasov, Oleg I EpsteinOOO “NPF “MATERIA MEDICA HOLDING”, Moscow, Russian FederationAbstract: Experimentally and clinically, it was shown that released-active form of ...
Gorbunov EA, Ertuzun IA, Kachaeva EV, Tarasov SA, Epstein OI   +4 more
doaj  

Synthesis and radioligand-binding assay of 2,5-disubstituted thiadiazoles and evaluation of their anticonvulsant activities

, 2020
In this study, a number of 2,5-disubstituted 1,3,4-thiadiazoles were synthesized using an appropriate synthetic route, and their anticonvulsant activity was determined by the maximal electroshock seizure (MES) test and their neurotoxicity was evaluated ...
Faizi, M., Shojaei, R., Toolabi, M., Khoramjouy, M., Asadipour, A., Ayati, A., Foroumadi, A., Shahhosseini, S., Firoozpour, L., Divsalar, K., Aghcheli, A., Moghimi, S.   +11 more
core  

A New Radioligand Binding Assay to Measure the Concentration of Drugs in Rodent Brain Ex Vivo [PDF]

, 2020
We have developed a new radioligand binding assay method to measure the concentration of nonradiolabeled drugs in the brain ex vivo. This new method fuses the concepts of standard competition and saturation binding assays and uses a transformed version ...
G Patrick Hussmann, Kenneth J Kellar
core  

When a Prophecy comes True: Ethyleneoxynitazene as a ‘Prophetic’ Member of the Emerging Class of 2-Benzylbenzimidazole ‘Nitazene’ Synthetic Opioids

Emerging Trends in Drugs, Addictions, and Health
Introduction: 2-Benzylbenzimidazole opioids (‘nitazenes’) have become increasingly prevalent on the recreational drug market. We performed pharmacological characterization of various 'prophetic' nitazenes, allowing risk prioritization based on structure ...
M.M. Vandeputte, G.C. Glatfelter, D. Walther, I. Ujváry, D.M. Iula, M.H. Baumann, C.P. Stove   +6 more
doaj   +1 more source

Correlation between the data obtained from platypus Mel1c and those obtained with clawed frog Mel1c.

, 2018
Data were obtained in a binding assay with 2-[125I]-iodomelatonin as the radioligand. See Fig 5.
Céline Legros (588091), Valerie Simonneaux (4952047), Isabelle Riest-Fery (4952035), Célia Gautier (4952038), Olivier Nosjean (414204), Frank Grützner (42240), Jean A. Boutin (229503), Sophie-Penelope Guenin (4952044), Tahlia Jade Perry (4952041)   +8 more
core   +1 more source

Radioligand binding and activation properties of M₂ receptor mutants.

Radioligand binding and activation properties of M2 receptor mutants.
Marco Scarselli (213524), Andrew B. Tobin (7589429), Cristina Pellegrini (4382356), Sebastian Diecke (7623965), Kostas Tokatlidis (2090884), Martin J. Lohse (250713), Paolo Annibale (213517), Francesco Marampon (759278), Anna R. Taddei (18462433), Alexandra Roman (9253410), Fernanda Amicarelli (301450), Eve Charlesworth (18462445), Bärbel Pohl (18462436), Irene Fasciani (18462418), Narasimha Telugu (18462421), Ilaria Pietrantoni (9313387), Franco Giorgi (18462448), Ruairidh Edwards (6532070), Vincenzo Flati (3753451), Maria E. Terzenidou (18462427), Silvano Santini Jr (18462430), Henrik Zauber (2029174), Francesco Petragnano (9313384), Marlies Grieben (18462424), Roberto Maggio (9313408), Jacopo Di Gregorio (3753448), Mario Rossi (3012018), Marco Carli (30619), Gabriella Aloisi (18462442), Ziming Wang (403663), Stefano Aringhieri (18462439), Ulrike Zabel (2297950)   +31 more
core   +1 more source