Results 51 to 60 of about 333 (138)

Combination of natural polyphenols with a precursor of NAD + and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation [PDF]

Introduction Effective agents that could confer long-term protection against ionizing radiation in vivo would have applications in medicine, biotechnology, and in air and space travel.
Salvador Palmer, M. del Rosario, Sirerol, J. Antoni, Estrela Arigüel, José María, Villaescusa, Juan I., Obrador, Elena, Dellinger, Ryan W., Montoro Pastor, Alegría, Pellicer, Blanca, López-Blanch, Rafael   +8 more
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Presentation_1_Echocardiography Differentiates Lethally Irradiated Whole-Body From Partial-Body Exposed Rats.PPTX

, 2018
Background: Acute radiation syndrome (ARS) affects morbidity and mortality dependent on the amount of body exposed. We propose the use of echocardiography (EC) to differentiate between survivors and non-survivors by measuring changes in cardiac function (
Celeste Kanne (5857475), M. Waleed Gaber (3615281), Alireza Paikari (5857478), Taeko Inoue (360784), Caterina C. Kaffes (5857481), Omaima M. Sabek (3615272), Janice A. Zawaski (3615269), Poonam Sarkar (5857484), Vivien Sheehan (5857472)   +8 more
core   +1 more source

Triterpenoid CDDO-Me induces ROS generation and up-regulates cellular levels of antioxidative enzymes without induction of DSBs in human peripheral blood mononuclear cells

, 2020
Ionizing radiation produces reactive oxygen species (ROS) leading to cellular DNA damage. Therefore, patients undergoing radiation therapy or first responders in radiological accident scenarios could both benefit from the identification of specifically ...
Beinke, Christina, Scherthan, Harry, Hermann, Cornelius, Eder, Stefan, Port, Matthias, Popp, Tanja   +5 more
core   +1 more source

Accelerating the Development of Diagnostic Biomarkers and Mitigating Drugs for Radiation Injury with Quantitative Mass Spectrometry [PDF]

, 2019
Nuclear and radiological terrorism is an on-going public health concern, but very few effective measures exist to assess the extent of the injury or counter the injuries from these potential attacks.
Liu, Kate
core   +1 more source

Nanotechnology meets radiobiology: Fullerenols and Metallofullerenols as nano-shields in radiotherapy [PDF]

Despite significant advances in the development of radioprotective measures, the clinical application of radioprotectors and radiomitigators remains limited due to insufficient efficacy and high toxicity of most agents.
Obrador, Elena, Kolodziejczyk-Czepas, Joanna, Grebowski, Jacek, Jankowski, Maciej M., Litwinienko, Grzegorz, Kazmierska-Grebowska, Paulina   +5 more
core   +1 more source

Radioprotective and Radiomitigative Effects of Resveratrol in Radiation-Induced Reproductive Toxicity in Male Mice

Toxics
Background: Agents with free radical-scavenging functions may act as radiation modifiers, protectors, or mitigators. Methods: We investigated whether supplementation with resveratrol (RSV) in mice, at different times after the beginning of X-irradiation, may influence sperm count and quality during the irradiation and recovery.
Małgorzata M. Dobrzyńska, Aneta Gajowik   +1 more
openaire   +2 more sources

The Exploration of an Effective Medical Countermeasure Enhancing Survival and Hematopoietic Recovery and Preventing Immune Insufficiency in Lethally-Irradiated Mice

, 2020
Indiana University-Purdue University Indianapolis (IUPUI)There is an urgent demand for effective medical countermeasures (MCM) in the event of high-dose radiation exposure ranging from nuclear plant disasters to potential nuclear warfare.
Wu, Tong
core   +1 more source

Synthesis and Applications of One- and Two-Dimensional Polymer-Carbon Nanomaterial Composites [PDF]

, 2017
This dissertation describes the synthesis of polymer and carbon nanomaterial composites and their applications in drug delivery, chemical sensing, and catalytic oxidative patterning.
Seo, Wanji
core  

Nat Commun [PDF]

The risk of radionuclide release in terrorist acts or exposure of healthy tissue during radiotherapy demand potent radioprotectants/radiomitigators.

core  

Evaluation of the effect of professional irradiation on cytogenetic parameters of peripheral blood lymphocytes

, 2018
Выполнено цитогенетическое обследование радиологов с различным стажем работы в сфере действия ионизирующего излучения. Предварительные данные указывают на то, что у радиологов со стажем работы свыше 1,5 года примерно в 70 % случаев регистрируется ...
Дёмина, Э.А.
core   +1 more source