Results 41 to 50 of about 333 (138)
Role of some epigenetic factors in DNA damage response pathway
, 2017 The current review gives a brief account of the DNA damage response pathway and involvement of various epigenetic mechanisms in DNA damage response pathway.
Mrinalini Tiwari +2 more
core +1 more source
Immunological Reviews, Volume 329, Issue 1, January 2025.Summary Radiation, a universal component of Earth's environment, is categorized into non‐ionizing and ionizing forms. While non‐ionizing radiation is relatively harmless, ionizing radiation possesses sufficient energy to ionize atoms and disrupt DNA, leading to cell damage, mutation, cancer, and cell death.
Saurabh Saini, Prajwal Gurung
wiley +1 more source
Фармакопрофілактичні та фармакотерапевтичні підходи до послаблення пошкоджуючої дії іонізуючого опромінення: огляд інформаційних джерел [PDF]
, 2018 Гладких Ф. В. Фармакопрофілактичні та фармакотерапевтичні підходи до послаблення пошкоджуючої дії іонізуючого опромінення: огляд інформаційних джерел. Траєкторія науки = Traektoriâ Nauki = Path of Science. 2018. № 12. С.
Гладких, Ф.В.
core +2 more sources
Nomenclature of radioprotective medical agents for major radiation accidents
Радиационная гигиенаThe widespread use of nuclear and radiation technologies necessitates preparedness for response to radiological emergencies. The application of medical countermeasures aimed at mitigating the adverse effects of ionizing radiation is a key element of risk
G. A. Gorsky +3 more
doaj +1 more source
The public health implications of the use of radioprotectors and radiomitigators in cumulative ionizing radiation exposure [PDF]
, 2014 Cumulative exposure to natural and artificial ionizing radiation is a prevalent environmental health risk and is increasing. Ionizing radiation exposure may cause inheritable DNA mutations and increase cancer risks in exposed populations.
Dunn, Dina
core
Radiation Countermeasures: Current Status [PDF]
, 2017 Deleterious effects of ionising radiation leading to significant morbidity and mortality have been studied elaborately. A range of synthetic, semisynthetic and herbal compounds have been screened as radiation countermeasure agents and a number of ...
Gupta, Noopur +9 more
core +1 more source
A Review of Radiation-Induced Alterations of Multi-Omic Profiles, Radiation Injury Biomarkers, and Countermeasures [PDF]
, 2022 Increasing utilization of nuclear power enhances the risks associated with industrial accidents, occupational hazards, and the threat of nuclear terrorism.
Helikar, Tomáš +10 more
core
Atom Indonesia, 2020 In cases of radiological accidents, especially for victims exposed to high-dose total-body irradiation (TBI), the administration of appropriate approved hematopoietic drugs is the most rapid medical treatment for preventing severe acute radiation syndrome, which is associated with a high mortality rate.
T. Nishida +6 more
openaire +3 more sources
The FASEB Journal, 2013 Radiation exposure can occur either intentionally or unintentionally and few drugs have been shown to be effective in mitigating or treating the damaging effects of radiation. Flt3 Ligand (Flt3L, fms‐like tyrosine kinase 3 ligand, CDX‐301) is a hematopoietic cytokine which stimulates the proliferation and differentiation of various
Lawrence J. Thomas +9 more
openaire +1 more source
Radioprotective and radiomitigative effects of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, in two mouse strains exposed to total body irradiation [PDF]
International Journal of Radiation Biology, 2017 There remains an unmet medical need for radioprotective and mitigative agents. BP-C2 is a novel lignin-derived polyphenolic composition with ammonium molybdate, developed as radioprotector/radiomitigator.The present study evaluated BP-C2 for the mitigation of acute radiation syndrome (ARS).A total-body irradiation mouse model (TBI, 4.0-8.0 Gy) was used
Vladimir N. Bykov +9 more
openaire +2 more sources