Results 11 to 20 of about 22,462 (308)

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh   +5 more
wiley   +1 more source

Bio‐inspired functional coacervates

open access: yesAggregate, Volume 3, Issue 6, December 2022., 2022
Bio‐inspired functional coacervates have diverse functions. Natural and synthetic coacervates are a new class of materials that have great potential for various biomedical applications, including medical adhesives, drug delivery, and tissue engineering.
Shujun Chen, Qi Guo, Jing Yu
wiley   +1 more source

Artificial intelligence and the future of diagnostic and therapeutic radiopharmaceutical development: in Silico smart molecular design [PDF]

open access: yes, 2021
Novel diagnostic and therapeutic radiopharmaceuticals are increasingly becoming a central part of personalized medicine. Continued innovation in the development of new radiopharmaceuticals is key to sustained growth and advancement of precision medicine.
arxiv   +1 more source

Sulfur [18F]Fluoride Exchange Reaction Enables Rapid Access to 18F-Labeled PET Tracers

open access: yesMedical Sciences Forum, 2022
Efficient 18F-fluorination procedures for the production of radiopharmaceuticals are urgently needed to satisfy the increasing demand for clinical diagnostics using positron emission tomography (PET).
Austin Craig   +8 more
doaj   +1 more source

The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method [PDF]

open access: yesJournal of Pure and Applied Chemistry Research, 2021
Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown.
Amal Rezka Putra   +6 more
doaj  

Improved accuracy of S-value-based dosimetry: a guide to transition from Cristy–Eckerman to ICRP adult phantoms

open access: yesEJNMMI Physics, 2022
Background In 2016, the International Commission on Radiological Protection (ICRP) published the results of Monte Carlo simulations performed using updated and anatomically realistic voxelized phantoms. The resulting specific absorbed fractions are based
Shalini Subramanian   +5 more
doaj   +1 more source

Simultaneous Visualization of 161Tb- and 177Lu-Labeled Somatostatin Analogues Using Dual-Isotope SPECT Imaging

open access: yesPharmaceutics, 2021
The decay of terbium-161 results in the emission of β¯-particles as well as conversion and Auger electrons, which makes terbium-161 interesting for therapeutic purposes.
Francesca Borgna   +9 more
doaj   +1 more source

Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma

open access: yesBMC Cancer, 2018
Background Protein kinase inhibitors (PKIs) are currently tested in clinical studies (phase I-III) as an alternative strategy against (recurrent) ovarian cancer.
Dennis Lindenblatt   +8 more
doaj   +1 more source

Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

open access: yesOncoImmunology, 2020
Chimeric antigen receptor (CAR) T cells show remarkable therapeutic effects in some hematological malignancies. However, CAR T cells can also cause life-threatening side effects.
Anja Feldmann   +12 more
doaj   +1 more source

Pharmacovigilance in radiopharmaceuticals

open access: yesIndian Journal of Nuclear Medicine, 2016
Indian Pharmacopoeia Commission is Committed for maintaining the standards of drugs including Radiopharmaceuticals (RPs) by publishing Indian Pharmacopoeia. These RPs are being used in India for diagnostic or therapeutic purpose. RPs though contain relatively small quantities of active ingredient and administered in small volumes could cause some ...
Rakesh Kumar   +4 more
openaire   +4 more sources

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