Results 31 to 40 of about 26,238 (200)

Simultaneous Visualization of 161Tb- and 177Lu-Labeled Somatostatin Analogues Using Dual-Isotope SPECT Imaging

open access: yesPharmaceutics, 2021
The decay of terbium-161 results in the emission of β¯-particles as well as conversion and Auger electrons, which makes terbium-161 interesting for therapeutic purposes.
Francesca Borgna   +9 more
doaj   +1 more source

Leveraging National Cancer Institute Programmatic Collaboration for Single Radiopharmaceutical Drug Master Files

open access: yesFrontiers in Oncology, 2019
Targeted radiopharmaceutical conjugates intended for therapeutic use often are made of three key components, a decaying radionuclide, a chemical chelator/linker, and a targeted molecular entity.
Charles A. Kunos   +2 more
doaj   +1 more source

Improved accuracy of S-value-based dosimetry: a guide to transition from Cristy–Eckerman to ICRP adult phantoms

open access: yesEJNMMI Physics, 2022
Background In 2016, the International Commission on Radiological Protection (ICRP) published the results of Monte Carlo simulations performed using updated and anatomically realistic voxelized phantoms. The resulting specific absorbed fractions are based
Shalini Subramanian   +5 more
doaj   +1 more source

Radiopharmaceuticals in cardiology

open access: yesNuclear Medicine Review, 2012
Myocardial perfusion studies are among the most often performed investigations in Nuclear Medicine. However, the development of radiopharmaceuticals for cardiology is an emerging discipline and several other radiotracers have been proven to be useful.
Renata, Mikołajczak, Piotr, Garnuszek
openaire   +3 more sources

Pharmacovigilance in radiopharmaceuticals

open access: yesIndian Journal of Nuclear Medicine, 2016
Indian Pharmacopoeia Commission is Committed for maintaining the standards of drugs including Radiopharmaceuticals (RPs) by publishing Indian Pharmacopoeia. These RPs are being used in India for diagnostic or therapeutic purpose. RPs though contain relatively small quantities of active ingredient and administered in small volumes could cause some ...
Kumar, Rishi   +4 more
openaire   +3 more sources

Standardization of the [68Ga]Ga-PSMA-11 Radiolabeling Protocol in an Automatic Synthesis Module: Assessments for PET Imaging of Prostate Cancer

open access: yes, 2021
Prostate-specific membrane antigen (PSMA) is a glycoprotein present in the prostate, that is overexpressed in prostate cancer (PCa). Recently, PSMA-directed radiopharmaceuticals have been developed, allowing the pinpointing of tumors with the Positron ...
Marcelo L. da Cunha   +8 more
core   +1 more source

A qualitative evaluation on the appropriateness of the current regulatory guidelines, on the manufacture of medicines within the radiopharmaceutical industry [PDF]

open access: yes, 2016
Magister Pharmaceuticae - MPharmThe purpose of this research thesis, is to evaluate the appropriateness of the current regulatory guidelines on the manufacture of medicinal products within the radiopharmaceutical industry.
Suliman, Zaahirah
core   +1 more source

Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy—A Hypothesis-Driven Review

open access: yesAntioxidants, 2016
Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients. Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side effects with severe acute and late pathophysiological consequences ...
Markus Laube   +2 more
doaj   +1 more source

Radiopharmaceutical Therapy [PDF]

open access: yesHealth Physics, 2019
Abstract Radiopharmaceutical therapy involves the use of radionuclides that are either conjugated to tumor-targeting agents (e.g., nanoscale constructs, antibodies, peptides, and small molecules) or that concentrate in tumors through natural physiological mechanisms that occur predominantly in neoplastic cells.
openaire   +2 more sources

Radiopharmaceutical Production for PET Imaging in Poland [PDF]

open access: yes, 2015
At the beginning of 2000 the PET technique was not available in Poland. The structure and organization of the Radiopharmaceuticals Production and Research Centre at the Heavy Ion Laboratory, University of Warsaw is described as an example of a production
Choiński, J.
core   +1 more source

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