Results 41 to 50 of about 47,032 (177)

Improved accuracy of S-value-based dosimetry: a guide to transition from Cristy–Eckerman to ICRP adult phantoms

EJNMMI Physics, 2022
Background In 2016, the International Commission on Radiological Protection (ICRP) published the results of Monte Carlo simulations performed using updated and anatomically realistic voxelized phantoms. The resulting specific absorbed fractions are based
Shalini Subramanian, Bin He, Eric Frey, Derek W. Jokisch, Wesley Bolch, George Sgouros   +5 more
doaj   +1 more source

Comparative evaluation of [(99m)tc]tilmanocept for sentinel lymph node mapping in breast cancer patients: results of two phase 3 trials. [PDF]

, 2013
BackgroundSentinel lymph node (SLN) surgery is used worldwide for staging breast cancer patients and helps limit axillary lymph node dissection.
Avisar, Eli, Christman, Lori, Cox, Charles, Deck, Kenneth, Faries, Mark, Frazier, Thomas G, Hall, Nathan C, Han, Linda K, Hoh, Carl K, King, Dennis W, Krontiras, Helen, Limmer, Karl K, Povoski, Stephen P, Schneebaum, Schlomo, Vera, David R, Wallace, Anne M   +15 more
core   +2 more sources

In vivo evaluation of TNF-alpha in the lungs of patients affected by sarcoidosis [PDF]

, 2015
Introduction. Sarcoidosis is a multisystemic granulomatous disorder characterized by multiple noncaseating granulomas involving intrathoracic lymph nodes and lung parenchyma.
BRUNO, PIERDONATO, GALLI, FILIPPO, LANZOLLA, TIZIANA, Malviya, Gaurav, MARIOTTA, Salvatore, PIETRANGELI, VITTORIO, Ragni, Paola, RICCI, Alberto, SCOPINARO, Francesco, SIGNORE, Alberto   +9 more
core   +5 more sources

Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na^99mTcO₄) and on the fixation of radioactivity on blood constituents [PDF]

, 2008
This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca, Benarroz M. O., Bernardo-Filho M., Capriles P. V., Claudia Leite Diniz, Danielle Santos de Almeida, Fernanda Santos do Carmo, Fonseca A. S., Frydman J. N. G., Goel H. C., Inamdar P. K., Jayashree G., Mario Bernardo Filho, Moreno S.R., Owunwanne A., Padma P. R., Rebello B. M., Saha G. B., Sebastião David Santos-Filho, Sharma J., Shobi V., Simões C. M. O., Sotiris Missailidis   +22 more
core   +4 more sources

Lutathera®: The First FDA- and EMA-Approved Radiopharmaceutical for Peptide Receptor Radionuclide Therapy

Pharmaceuticals, 2019
As the first radiopharmaceutical for Peptide Receptor Radionuclide Therapy (PRRT), Lutathera® was approved by the EMA in 2017 and the FDA in 2018 for the treatment of somatostatin receptor (SSTR) positive gastroenteropancreatic neuroendocrine tumors ...
Ute Hennrich, K. Kopka
semanticscholar   +1 more source

Current Status of Radiopharmaceutical Therapy.

International Journal of Radiation Oncology, Biology, Physics, 2020
In radiopharmaceutical therapy (RPT), a radionuclide is systemically or locally delivered with the goal of targeting and delivering radiation to cancer cells while minimizing radiation exposure to untargeted cells.
S. St. James, B. Bednarz, S. Benedict, J. Buchsbaum, Y. Dewaraja, E. Frey, R. Hobbs, J. Grudzinski, Emilie Roncali, G. Sgouros, J. Capala, Ying Xiao   +11 more
semanticscholar   +1 more source

Semiconducting polymer nano-radiopharmaceutical for combined radio-photothermal therapy of pancreatic tumor

Journal of Nanobiotechnology, 2021
Background Pancreatic ductal adenocarcinoma (PDAC) is a devastatingly malignant tumor with a high mortality. However, current strategies to treat PDAC generally have low efficacy and high side-effects, therefore, effective treatment against PDAC remains ...
Xiumin Shi, Qing Li, Chuan Zhang, Hailong Pei, Guanglin Wang, Hui Zhou, Longfei Fan, Kai Yang, Bo Jiang, Feng Wang, Ran Zhu   +10 more
semanticscholar   +1 more source

Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy—A Hypothesis-Driven Review

Antioxidants, 2016
Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients. Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side effects with severe acute and late pathophysiological consequences ...
Markus Laube, Torsten Kniess, Jens Pietzsch   +2 more
doaj   +1 more source

Radiopharmaceutical Chemistry and Drug Development-What's Changed?

Seminars in Radiation Oncology, 2021
Radiation oncologists and nuclear medicine physicians have seen a resurgence in the clinical use of radiopharmaceuticals for the curative or palliative treatment of cancer.
C. Kunos, D. Mankoff, M. Schultz, S. Graves, D. Pryma   +4 more
semanticscholar   +1 more source

A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides

EJNMMI Research, 2023
Purpose The angiotensin converting enzyme-2 (ACE2)—entry receptor of SARS-CoV-2—and its homologue, the angiotensin-converting enzyme (ACE), play a pivotal role in maintaining cardiovascular homeostasis.
Darja Beyer, Christian Vaccarin, Xavier Deupi, Ana Katrina Mapanao, Susan Cohrs, Fan Sozzi-Guo, Pascal V. Grundler, Nicholas P. van der Meulen, Jinling Wang, Matthias Tanriver, Jeffrey W. Bode, Roger Schibli, Cristina Müller   +12 more
doaj   +1 more source