Results 61 to 70 of about 27,148 (204)
From radiotracer to radiopharmaceutical: a philosophical approach
, 2021 Radiotracer, radiopharmaceutical: one name, one word. It looks unimportant in a world which depends upon com- munication, constantly overwhelmed by a flood of words.
Todde, Sergio +3 more
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Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Technology Transfer of O-(2-[18F] Fluoroethyl)-L-Tyrosine (IASOglio®) Radiopharmaceutical
Background/Objectives: Gliomas, including the most aggressive subtype—glioblastoma multiforme, are brain tumors with an unfavorable prognosis and high mortality. Early diagnosis is essential to improve treatment efficacy.
Alessia Danti +9 more
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Radiopharmaceutical pharmacokinetics in animals: critical considerations [PDF]
, 2009 Since the advent of single photon emission computerized tomography (SPECT) and positron emission tomography (PET) various chemical ligands have been labeled with radionuclides and evaluated as tracer compounds in animal models to ascertain their ...
GIRON, MARIA CECILIA
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Preparation and in vitro evaluation of 177Lu-iPSMA-RGD as a new heterobivalent radiopharmaceutical [PDF]
, 2017 This study aimed to synthesize a new 177Lu-iPSMA-RGD heterobivalent radiopharmaceutical, as well as to assess the in vitro radiopharmaceutical potential to target cancer cells overexpressing PSMA and a(v) b(3) integrins.
ISAAC OLIVE, KEILA +26 more
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Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry
Bulletin of the Korean Chemical Society, EarlyView.Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah +8 more
wiley +1 more source
Prospective of ⁶⁸Ga-radiopharmaceutical development
, 2013 Positron Emission Tomography (PET) experienced accelerated development and has become an established method for medical research and clinical routine diagnostics on patient individualized basis.
Velikyan, Irina,
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Radiopharmaceutical good practices: Regulation between hospital and industry
, 2022 International audienceRadiopharmaceutical practices are divided into large-scale industrial manufacturing and small-scale “in-house” hospital radiopharmacy unit.
Bourgeois, Mickaël +2 more
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Clinical Pharmacology &Therapeutics, EarlyView.Project Orbis, launched by the US FDA in 2019, enables collaboration among international regulatory agencies on cancer drug reviews. We assessed the regulatory impact of Project Orbis in Canada by analyzing publicly available data on marketing authorization applications (MAAs).
Jonathan Zaslavsky, David C. Sealey
wiley +1 more source
Factors influencing the in vivo behavior of In(III)S3N and Ga(III)S3N
, 1997 Proceedings of the XIIth International Symposium on Radiopharmaceutical ...
L. A. JONES +10 more
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