Results 61 to 70 of about 26,238 (200)

Production of the PET radionuclide 61Cu via the 62Ni(p,2n)61Cu nuclear reaction

open access: yesEJNMMI Radiopharmacy and Chemistry
Background There are only a handful of true theranostic matched pairs, and in particular the theranostic radiocopper trio 61Cu, 64Cu and 67Cu, for diagnosis and therapy respectively, is a very attractive candidate. In fact, the alternative of two imaging
Santiago Andrés Brühlmann   +3 more
doaj   +1 more source

Technology Transfer of O-(2-[18F] Fluoroethyl)-L-Tyrosine (IASOglio®) Radiopharmaceutical

open access: yes
Background/Objectives: Gliomas, including the most aggressive subtype—glioblastoma multiforme, are brain tumors with an unfavorable prognosis and high mortality. Early diagnosis is essential to improve treatment efficacy.
Alessia Danti   +9 more
core   +1 more source

Synthesis and preclinical evaluation of FAP-targeting radiotracers for PET and optical imaging

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Successful treatment of solid cancers relies on precise diagnosis, e.g. using noninvasive molecular imaging, followed by surgical removal and/or chemo/immunotherapy.
Jürgen Kogler   +4 more
doaj   +1 more source

Investigation of the Putative Relationship Between Copper Transport and the Anticancer Activity of Cisplatin in Ductal Pancreatic Adenocarcinoma

open access: yesCells
Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous cancer with a severe stromal reaction mediated by pancreatic stellate cells (PSCs), leading to increased resistance to chemotherapy and radiotherapy.
Alina Doctor   +3 more
doaj   +1 more source

Cardiovascular disease and radiopharmaceutical therapies:an underestimated risk? [PDF]

open access: yes
In conclusion, although a clear relationship between radiation exposure from radiopharmaceutical therapy and CVD has not yet been established with scientific certainty, there is sufficient evidence in the literature to suggest that such a relationship ...
Lassmann, Michael   +2 more
core   +1 more source

Radiopharmaceutical pharmacokinetics in animals: critical considerations [PDF]

open access: yes, 2009
Since the advent of single photon emission computerized tomography (SPECT) and positron emission tomography (PET) various chemical ligands have been labeled with radionuclides and evaluated as tracer compounds in animal models to ascertain their ...
GIRON, MARIA CECILIA
core  

Designing assessment for radiopharmaceutical scientist training

open access: yes, 2017
ACER is working with radiopharmaceutical scientists to develop fit-for-purpose progressive assessment practices for a new training program, as Jacob Pearce ...
Pearce, Jacob
core   +2 more sources

Annual Report 2003 - Institute of Bioinorganic and Radiopharmaceutical chemistry [PDF]

open access: yes, 2004
The report gives an overview on the activities of the Institute ofBioinorganic and Radiopharmaceutical Chemistry in ...
Spies, H., Seifert, S.
core   +3 more sources

Bridging from Brain to Tumor Imaging: (S)-(−)- and (R)-(+)-[18F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice

open access: yesMolecules, 2018
Sigma-1 receptors (Sig1R) are highly expressed in various human cancer cells and hence imaging of this target with positron emission tomography (PET) can contribute to a better understanding of tumor pathophysiology and support the development of ...
Mathias Kranz   +12 more
doaj   +1 more source

Translational approach to radiopharmaceutical development

open access: yes, 2019
International audienceNuclear medicine, which encompasses the medical field of molecular imaging and radionuclide therapy, brings together many disciplines, and radiopharmacy requires that pharmacy, physics and medicine work together within a synergetic ...
Fragoso Costa, Pedro, Rbah-Vidal, Latifa
core   +3 more sources

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