Results 81 to 90 of about 47,032 (177)

Radiosensitization of noradrenaline transporter-expressing tumour cells by proteasome inhibitors and the role of reactive oxygen species [PDF]

, 2013
Background The radiopharmaceutical 131I-metaiodobenzylguanidine (131I-MIBG) is used for the targeted radiotherapy of noradrenaline transporter (NAT)-expressing neuroblastoma.
Babich, J.W., Boyd, M., Mairs, R.J., Rae, C., Tesson, M.   +4 more
core   +3 more sources

Evaluation of imaging protocol for ECT based on CS image reconstruction algorithm

, 2013
SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality and the ...
Cao, Xuexiang, Huang, Xianchao, Liu, Shuangquan, Wang, Lu, Wei, Long, Yun, Minkai, Zhou, Xiaolin   +6 more
core   +1 more source

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Brinkbäumer, K., Hahn, K., Keßler, M., Linke, R., Sommer, H., Tiling, R., Untch, M.   +6 more
core   +1 more source

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics [PDF]

, 2019
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR ...
Beattie, Bradley J., Beattie, Kai A., Elgqvist, Jörgen, Eriksson, Sophie E., Larsson, Erik, Strand, Sven-Erik, Thorek, Daniel L. J., Timmermand, Oskar Vilhelmsson, Tran, Thuy A., Ulmert, David, Örbom, Anders   +10 more
core   +2 more sources

Global Issues of Radiopharmaceutical Access and Availability: A Nuclear Medicine Global Initiative Project

Journal of Nuclear Medicine, 2020
The Nuclear Medicine Global Initiative was formed in 2012 by 13 international organizations to promote human health by advancing the field of nuclear medicine and molecular imaging by supporting the practice and application of nuclear medicine. The first
C. Cutler, E. Bailey, Vijay Kumar, S. Schwarz, H. Bom, J. Hatazawa, D. Paez, P. Orellana, L. Louw, F. Mut, H. Kato, A. Chiti, S. Frangos, F. Fahey, G. Dillehay, S. Oh, D. Lee, S. Lee, Rodolfo Nuñez-Miller, G. Bandhopadhyaya, P. Pradhan, A. Scott   +21 more
semanticscholar   +1 more source

Production of the PET radionuclide 61Cu via the 62Ni(p,2n)61Cu nuclear reaction

EJNMMI Radiopharmacy and Chemistry
Background There are only a handful of true theranostic matched pairs, and in particular the theranostic radiocopper trio 61Cu, 64Cu and 67Cu, for diagnosis and therapy respectively, is a very attractive candidate. In fact, the alternative of two imaging
Santiago Andrés Brühlmann, Martin Walther, Klaus Kopka, Martin Kreller   +3 more
doaj   +1 more source

First-in-man evaluation of 124I-PGN650: A PET tracer for detecting phosphatidylserine as a biomarker of the solid tumor microenvironment [PDF]

, 2017
Purpose: PGN650 is a F(ab′) 2 antibody fragment that targets phosphatidylserine (PS), a marker normally absent that becomes exposed on tumor cells and tumor vasculature in response to oxidative stress and increases in response to therapy.
Dehdashti, Farrokh, Freimark, Bruce D, Frye, Jennifer, Frye, Sarah, Laforest, Richard, Liu, Yongjian, Luehmann, Hannah, Shan, Joseph S, Siegel, Barry A, Sultan, Deborah   +9 more
core   +2 more sources

Synthesis and preclinical evaluation of FAP-targeting radiotracers for PET and optical imaging

EJNMMI Radiopharmacy and Chemistry
Background Successful treatment of solid cancers relies on precise diagnosis, e.g. using noninvasive molecular imaging, followed by surgical removal and/or chemo/immunotherapy.
Jürgen Kogler, Cornelius K. Donat, Johanna Trommer, Klaus Kopka, Sven Stadlbauer   +4 more
doaj   +1 more source

Studies on ToF-PET using Cherenkov radiation [PDF]

, 2015
La tomografia ad emissione di positroni (PET) è una tecnica di imaging di medicina nucleare, utilizzata oggi diffusamente in ambito clinico. Essa fornisce immagini e informazioni fisiologiche dei processi funzionali all’interno del corpo.
La Rosa, Francesco
core  

Overcoming Barriers to Radiopharmaceutical Therapy: An Overview from the NRG-NCI Working Group on Dosimetry of Radiopharmaceutical Therapy (RPT).

International Journal of Radiation Oncology, Biology, Physics, 2020
Radiopharmaceutical Therapy (RPT) continues to demonstrate tremendous potential in improving the therapeutic gains in radiation therapy by specifically delivering radiation to tumors that can be well assessed in terms of dosimetry and imaging.
C. Divgi, J. Carrasquillo, R. Meredith, Y. Seo, E. Frey, W. Bolch, B. Zimmerman, G. Akabani, Daniel A. Jacobson, B. Brown, S. Davern, R. Hobbs, J. Humm, E. Moros, D. Morse, R. Papineni, P. Zanzonico, S. Benedict, G. Sgouros   +18 more
semanticscholar   +1 more source