Results 91 to 100 of about 27,148 (204)

Production of Medical Radionuclides in the Center for Radiopharmaceutical Tumor Research—A Status Report

open access: yes
A new Center for Radiopharmaceutical Cancer Research was established at the Helmholtz-Zentrum Dresden-Rossendorf in 2017 to centralize radionuclide and radiopharmaceutical production, as well as enable chemical and biochemical research.
Klaus Kopka   +4 more
core   +1 more source

Radiopharmaceutical-induced bystander effect

open access: yes, 2007
Indirect effects may contribute to the efficacy of radiotherapy by sterilizing malignant cells that are not directly irradiated. However, little is known of the influence of indirect effects in targeted radionuclide treatment.
Zalutsky, Michael R   +3 more
core   +2 more sources

Cross‐Cohort Evidence Links KCNJ6 rs702859 to Impulsive–Compulsive Phenotypes in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Impulse control disorders (ICDs) and related compulsive behaviors (CBs) are frequent non‐motor complications of Parkinson's disease (PD) with a probable genetic contribution. Objective To investigate whether genetic variants involved in reward and punishment processing are associated with impulsive–compulsive phenotypes in PD ...
Sergio García‐Díaz   +21 more
wiley   +1 more source

Evaluation of resazurin phenoxazine dye as a highly sensitive cell viability potency assay for natural killer cell‐derived extracellular vesicle‐based cancer biotherapeutics

open access: yesJournal of Extracellular Biology
Natural killer cell‐derived extracellular vesicles (NK‐EVs) are candidate biotherapeutics against various cancers. However, standardised potency assays are necessary for a reliable assessment of NK‐EVs' cytotoxicity.
Frederic St‐Denis‐Bissonnette   +14 more
doaj   +1 more source

177Lu‐labeled amidoxime‐functionalized biodegradable microspheres for transarterial radioembolization of hepatocellular carcinoma

open access: yesPrecision Radiation Oncology, EarlyView.
Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu   +7 more
wiley   +1 more source

Structure–activity relationship of 18F-labeled PD-L1-targeting small molecule ligands: impact of radiolabeling strategy on affinity and in vivo performance

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Immune checkpoint inhibitor therapy addressing the PD-1/PD-L1 axis is a promising approach in cancer treatment. A clinically suitable radiotracer would allow molecular imaging of the temporospatial changes in tumor PD-L1 expression. This could
Fabian Krutzek   +2 more
doaj   +1 more source

Stereotactic Prostate Cancer Ablative Re‐Irradiation: A Systematic Review and Meta‐Analysis (SPARE)

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Stereotactic ablative radiotherapy (SABR) is emerging as an alternative treatment for patients with locally recurrent prostate cancer after previous radiation. This approach allows for precise target coverage while limiting toxicity to surrounding organs.
Andre G. Gouveia   +12 more
wiley   +1 more source

The Development of Novel Fluorescent and Radiopharmaceutical Probes for Imaging Neurodegenerative Diseases

open access: yes, 2020
Recent scientific advances in imaging technology mean the development of fluorescent and radiopharmaceutical probes have great potential for the measurement of pathological processes involved in various diseases, including neurodegenerative diseases and ...
Hendris Wongso (11913381)
core   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

open access: yesSmall, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom   +6 more
wiley   +1 more source

Quantitative Dual‐Energy CT Perfusion Versus SPECT/CT V/Q Scintigraphy for Preoperative Lung Function Assessment: A Prospective Cohort Study

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Accurate preoperative physiological assessment is critical for high‐risk patients undergoing lung resection to predict postoperative lung function. This study compared quantitative dual‐energy CT (DECT) perfusion with SPECT/CT for lobar perfusion mapping in an at‐risk oncological cohort.
Jack Edward Liu   +6 more
wiley   +1 more source

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