Results 91 to 100 of about 47,032 (177)

Investigation of the Putative Relationship Between Copper Transport and the Anticancer Activity of Cisplatin in Ductal Pancreatic Adenocarcinoma

Cells
Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous cancer with a severe stromal reaction mediated by pancreatic stellate cells (PSCs), leading to increased resistance to chemotherapy and radiotherapy.
Alina Doctor, Jonas Schädlich, Sandra Hauser, Jens Pietzsch   +3 more
doaj   +1 more source

Focal Spot, Spring/Summer 1980 [PDF]

, 1980
https://digitalcommons.wustl.edu/focal_spot_archives/1026/thumbnail ...

core   +1 more source

Enhanced contrast in FAP-targeting PET imaging with 61Cu-labeled FAP inhibitors: development and preclinical evaluation of novel [61Cu]Cu-Kalios PET radioligands

EJNMMI Radiopharmacy and Chemistry
Background Fibroblast activation protein (FAP)-targeting radioligands have gained attention for the ability to image multiple tumor types. Current FAP-targeting radioligands are labeled with 68Ga and 18F, but their short half-lives limit distribution ...
Jacopo Millul, Tais Basaco Bernabeu, Raghuvir H. Gaonkar, Francesco De Rose, Leila Jaafar-Thiel, Gary A. Ulaner, Rosalba Mansi, Melpomeni Fani   +7 more
doaj   +1 more source

Internal radiation dose assessment of radiopharmaceuticals prepared with cyclotron-produced 99m Tc [PDF]

, 2019
Technetium-99m (99m Tc) is the radioisotope most widely used in diagnostic nuclear medicine. It is readily available from 99 Mo/99m Tc generators as the \u3b2- decay product of the 99 Mo (T\ubd =66 h) parent nuclide.
Bello, Michele, De Nardo, Laura, Esposito, Juan, Ferro-Flores, Guillermina, Mel\ue9ndez-Alafort, Laura, Negri, Anna, Paiusco, Marta, Rosato, Antonio, Uzunov, Nikolay, Zorz, Alessandra   +9 more
core   +1 more source

Evaluation of Actinium-225 Labeled Minigastrin Analogue [²²⁵Ac]Ac-DOTA-PP-F11N for Targeted Alpha Particle Therapy

Pharmaceutics, 2020
The overexpression of cholecystokinin B receptor (CCKBR) in human cancers led to the development of radiolabeled minigastrin analogues for targeted radionuclide therapy, which aims to deliver cytotoxic radiation specifically to cancer cells.
Yun Qin, Stefan Imobersteg, Alain Blanc, Stephan Frank, Roger Schibli, Martin P. Béhé, Michal Grzmil   +6 more
doaj   +1 more source

Functional brain imaging : a brief overview of imaging techniques and their use in human and canine anxiety research [PDF]

, 2011
When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and
Audenaert, Kurt, De Meester, Rudy, Dobbeleir, André, Peremans, Kathelijne, van Bree, Henri, Vandermeulen, Eva, Vermeire, Simon   +6 more
core  

Scintigraphic assessment of bone status at one year following hip resurfacing : comparison of two surgical approaches using SPECT-CT scan [PDF]

, 2012
Objectives: To study the vascularity and bone metabolism of the femoral head/neck following hip resurfacing arthroplasty, and to use these results to compare the posterior and the trochanteric-flip approaches.
Amarasekera HW, Amarasekera HW, Beaulé PE, Beaulé PE, Bolland BJ, Calder SJ, Carrothers AD, Cheng D, Collier BD, Crock HV, Fordyce MJ, Forrest N, Freeman MA, Ganz R, Gholamrezanejhad A, Horger M, Jiang Y, Khan A, Koch GG, Linke R, Mariani G, McMahon SJ, Patterson AH, Prime MS, Ryu JS, Scharf S, Shimmin AJ, Steffen RT, Steffen RT, Thickman D, van der Bruggen W, Whiteside LA   +31 more
core   +1 more source

Phase 0 Radiopharmaceutical–Agent Clinical Development

Frontiers in Oncology, 2020
The evaluation of antibody-targeted or peptide-targeted radiopharmaceuticals as monotherapy or in oncological drug combinations requires programmatic collaboration within the National Cancer Institute (NCI) clinical trial enterprise.
C. Kunos, L. Rubinstein, J. Capala, M. A. McDonald   +3 more
semanticscholar   +1 more source

Bridging from Brain to Tumor Imaging: (S)-(−)- and (R)-(+)-[18F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice

Molecules, 2018
Sigma-1 receptors (Sig1R) are highly expressed in various human cancer cells and hence imaging of this target with positron emission tomography (PET) can contribute to a better understanding of tumor pathophysiology and support the development of ...
Mathias Kranz, Ralf Bergmann, Torsten Kniess, Birgit Belter, Christin Neuber, Zhengxin Cai, Gang Deng, Steffen Fischer, Jiangbing Zhou, Yiyun Huang, Peter Brust, Winnie Deuther-Conrad, Jens Pietzsch   +12 more
doaj   +1 more source

Determination of Radiochemical Purity of 99mTc-DTPA Using One-System Method of Paper Chromatography [PDF]

Journal of Pure and Applied Chemistry Research, 2019
The more efficient and effective quality control techniques for 99mTc-DTPA are needed because 99mTc has a short half-life of around 6.0 hours. We have succeeded in developing a one-system of TLC for radiochemical purity testing system that is faster and ...
Maskur Maskur, Enny Lestari, Amal Rezka Putra, Dede Kurniasih, Endang Sarmini, Yayan Tahyan, Adang Hardi Gunawan, Arni Aries   +7 more
doaj