Results 71 to 80 of about 12,450 (234)
Focal Spot, Spring/Summer 1980 [PDF]
, 1980 https://digitalcommons.wustl.edu/focal_spot_archives/1026/thumbnail ...
core +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.A novel puromycin linker for cDNA display was synthesized via SPAAC reaction. Its functionality was confirmed by recovering intact DNA after selection against EpCAM. The system also enabled the verification of bicyclic peptides during display, demonstrating its utility for constructing and screening structurally complex peptide libraries.
Simon Schneider +3 more
wiley +1 more source
Terbium-149 production: a focus on yield and quality improvement towards preclinical application
Scientific ReportsTerbium-149 (T1/2 = 4.1 h, Eα = 3.98 MeV (16.7%), 28 µm range in tissue) is a radionuclide with potential for targeted alpha therapy. Due to the negligible emission of α-emitting daughter nuclides, toxicity to healthy tissue may be reduced in comparison ...
C. Favaretto +11 more
doaj +1 more source
Comparison of desferrioxamine and NODAGA for the gallium-68 labeling of exendin-4
EJNMMI Radiopharmacy and Chemistry, 2019 Introduction Radiolabeled exendin-4 (Ex4) derivatives are used to target the glucagon-like peptide-1 receptor (GLP-1R) for the clinical diagnosis of insulinomas, a rare type of neuroendocrine tumor.
Simon A. M. Kaeppeli +3 more
doaj +1 more source
Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers
Scientific Reports, 2023 The heterogenous treatment response of tumor cells limits the effectiveness of cancer therapy. While this heterogeneity has been linked to cell-to-cell variability within the complex tumor microenvironment, a quantitative biomarker that identifies and ...
Tina Pekeč +7 more
doaj +1 more source
Functional brain imaging : a brief overview of imaging techniques and their use in human and canine anxiety research [PDF]
, 2011 When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and
Audenaert, Kurt +6 more
core
Internal radiation dose assessment of radiopharmaceuticals prepared with cyclotron-produced 99m Tc [PDF]
, 2019 Technetium-99m (99m Tc) is the radioisotope most widely used in diagnostic nuclear medicine. It is readily available from 99 Mo/99m Tc generators as the \u3b2- decay product of the 99 Mo (T\ubd =66 h) parent nuclide.
Bello, Michele +9 more
core +1 more source
Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science). Progress report, January 1, 1992--December 31, 1992 [PDF]
, 1992 This report describes three studies aimed at using radiolabeled pharmaceuticals to explore brain function and anatomy. The first section describes the chemical preparation of [F18]fluorinated benzamides (dopamine D-2 receptor tracers), [F18]fluorinated benzazepines (dopamine D-1 receptor tracers), and tissue distribution of [F18]-fluoxetine (serotonin ...
Cooper, M., Beck, R. N.
openaire +2 more sources
European Journal of Organic Chemistry, EarlyView.A simple bifunctional organocatalyst derived from the FDA‐approved chelator deferiprone efficiently promotes CO2 fixation into cyclic carbonates. By combining epoxide activation and nucleophilic ring opening in a single scaffold, quantitative conversions are achieved under mild, metal‐free conditions. High activity, broad substrate scope, and excellent
Erika Saccullo +6 more
wiley +1 more source