Results 91 to 100 of about 78,818 (344)

Preparation and Evaluation of Novel Folate Isonitrile ^99mTc Complexes as Potential Tumor Imaging Agents to Target Folate Receptors

Molecules, 2021
In order to seek novel technetium-99m folate receptor-targeting agents, two folate derivatives (CN5FA and CNPFA) were synthesized and radiolabeled to obtain [99mTc]Tc-CN5FA and [99mTc]Tc-CNPFA complexes, which exhibited high radiochemical purity (>95 ...
Junhong Feng, Xuran Zhang, Qing Ruan, Yuhao Jiang, Junbo Zhang   +4 more
doaj   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Design, Preparation, and Evaluation of a Novel ^99mTcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent

Molecules, 2020
In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [99mTcN]2+ core to obtain the 99mTcN-CPF2XT complex, which exhibited high radiochemical purity ...
Si’an Fang, Yuhao Jiang, Qianqian Gan, Qing Ruan, Di Xiao, Junbo Zhang   +5 more
doaj   +1 more source

The Study of {99}mTc-Aluminum Oxide Using for Sentinel Lymph Nodes Detection in Experiment [PDF]

, 2016
We have established a multiple higher accumulation of {99}mTc-Al[2]O[3] in SLM in comparison with import analogue. Considering this fact the clinical use of new domestic radiopharmaceutical will facilitate intraoperative identification of such ...
Bragina, Olga Dmitrievna, Chernov, Vladimir Ivanovich, Dergilev, A. P., Lyapunov, A. Yu., Medvedeva, Anna Aleksndrovna, Sinilkin, Ivan Gennadjevich, Skuridin, Viktor Sergeyevich, Varlamova, Natalya Valeryevna, Zelchan, Roman Vladimirovich   +8 more
core   +1 more source

A Picture of Modern Tc-99m Radiopharmaceuticals: Production, Chemistry, and Applications in Molecular Imaging

Applied Sciences, 2019
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-imaging applications. Its peculiar physical and chemical properties make it particularly suitable for medical imaging.
A. Boschi, L. Uccelli, P. Martini
semanticscholar   +1 more source

Oligonucleotides as Radiopharmaceuticals

, 2006
Oligonucleotide radiopharmaceuticals is a slowly but steadily progressing field. With a panel of labeling and imaging techniques mastered by several groups, imaging of oligonucleotides is now relatively accessible and will be applied to more and more trials of oligonucleotide pharmacology.
openaire   +3 more sources

FIGO recommendations on objective measurement of blood loss after birth for early detection of postpartum hemorrhage

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Postpartum hemorrhage (PPH) remains the leading cause of maternal mortality worldwide, particularly in resource‐constrained and remote settings. The cornerstone of reducing PPH‐related morbidity and mortality lies in its early recognition, timely treatment, and adherence to evidence‐based protocols, all of which are heavily dependent on an ...
Ferdousi Begum, Albaro J. Nieto‐Calvache, Dietmar Schlembach, Justus Hofmyer, Jose Palacios‐Jaraquemada, Ajey Bhardwaj, Maria A. Suarez, Juan M. Burgos‐Luna, Jolly Beyeza‐Kashesya, Akaninyene E. Ubom, Alison Wright, FIGO Committee on Childbirth and PPH   +11 more
wiley   +1 more source

SPECT and PET serve as molecular imaging techniques and in vivo biomarkers for brain metastases [PDF]

, 2014
Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases.
Buresta, Tommaso, Fravolini, Mario Luca, Nuvoli, Susanna Maria Francesca, Palumbo, Barbara, Palumbo, Isabella, Schillaci, Orazio, Spanu, Angela   +6 more
core   +2 more sources

Occupational burnout in nuclear medicine technologists working in Australia and New Zealand – results of a multi‐national survey

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 25-33, March 2025.
Occupational burnout is associated with negative feelings about the workplace and is often caused by a high workload and a non‐supportive workplace. It is associated with absenteeism, high turnover of staff and decreased patient care. More than half of the New Zealand participants and three quarters of the Australian participants had moderate levels of
Melissa Shields, Daphne James, Lynne McCormack   +2 more
wiley   +1 more source

Radiopharmaceuticals in the elderly cancer patient: Practical considerations, with a focus on prostate cancer therapy: A position paper from the International Society of Geriatric Oncology Task Force. [PDF]

, 2017
Molecular imaging using radiopharmaceuticals has a clear role in visualising the presence and extent of tumour at diagnosis and monitoring response to therapy. Such imaging provides prognostic and predictive information relevant to management, e.g.
Aapro, M., Dale, W., Gillessen, S., Oyen, W.J., Prior, J.O., Wirth, M.   +5 more
core   +1 more source