Flow optimization study of a batch microfluidics PET tracer synthesizing device. [PDF]
We present numerical modeling and experimental studies of flow optimization inside a batch microfluidic micro-reactor used for synthesis of human-scale doses of Positron Emission Tomography (PET) tracers.
Daridon, Antoine+7 more
core +4 more sources
Production Of 11C‐Labeled Amides Via “In‐Loop” 11C‐Carbonylation
The current work utilizes carbon‐11 labelled aroyl dimethylaminopyridinium salts in a two‐step in‐loop carbonylative cross‐coupling reaction of aryl halides with [¹¹C]CO yielding a diverse range of carbon‐11 labelled primary benzamides with good to excellent yields.
Tanpreet Kaur+3 more
wiley +1 more source
Background N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine transporter imaging, is a promising biomarker, as it reflects the severity of Parkinson’s disease (PD).
Jae Hun Ahn+9 more
doaj +1 more source
Feasibility study of the positronium imaging with the J-PET tomograph [PDF]
A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the object. In this paper we explore the possibility of performing the three gamma photons imaging based on ortho ...
arxiv +1 more source
Characterization in Geant4 of different PET configurations [PDF]
Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation in PET as well as improvement in electronic detectors (e.g., SiPMs) and signal processing, makes the field of PET
arxiv
The expanding role of nuclear medicine in therapeutic strategies [PDF]
The concept of carrying a cytotoxic radionuclide directly to cancerous cells is an attractive alternative to conventional forms of radiation treatment.
Aquilina, Mark Anthony
core
Development of 225Ac Radiopharmaceuticals: TRIUMF Perspectives and Experiences
Background: The development of radiopharmaceuticals containing 225Ac for targeted alpha therapy is an active area of academic and commercial research worldwide.
A. Robertson+3 more
semanticscholar +1 more source
Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life
Abstract INTRODUCTION Premenopausal bilateral oophorectomy (PBO) before the age of 46 years is associated with an increased risk of dementia. We investigated the long‐term effects of PBO performed before age 50 years on amyloid beta (Aβ), tau, and neurodegeneration imaging biomarkers of Alzheimer's disease (AD).
Kejal Kantarci+13 more
wiley +1 more source
Polycrystalline para-terphenyl scintillator adopted in a $β^-$ detecting probe for radio-guided surgery [PDF]
A radio-guided surgery technique exploiting $\beta^-$ emitters is under development. It aims at a higher target-to-background activity ratio implying both a smaller radiopharmaceutical activity and the possibility of extending the technique to cases with a large uptake of surrounding healthy organs.
arxiv +1 more source
Functional brain imaging : a brief overview of imaging techniques and their use in human and canine anxiety research [PDF]
When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and
Audenaert, Kurt+6 more
core