Results 41 to 50 of about 51,772 (325)

Role of AI in Theranostics: Towards Routine Personalized Radiopharmaceutical Therapies [PDF]

open access: yesarXiv, 2021
We highlight emerging uses of artificial intelligence (AI) in the field of theranostics, focusing on its significant potential to enable routine and reliable personalization of radiopharmaceutical therapies (RPTs). Personalized RPTs require patient-individual dosimetry calculations accompanying therapy.
arxiv  

Immunoscintigraphy for therapy decision making and follow-up of biological therapies [PDF]

open access: yes, 2016
With the availability of new biological therapies there is the need of more accurate diagnostic tools to noninvasively assess the presence of their targets.
Auletta, S.   +6 more
core   +2 more sources

Synthesis, Novel Crystal Structure, and β-Amyloid Binding Property of Re(I) (tricarbonyl)+ EHIDA Analogue

open access: yesBioinorganic Chemistry and Applications, 2009
A neutral compound Re(CO)3(L) (L: 2-((2-(2,6-diethylphenylamino)-2-oxoethyl)(2-ethoxy-2-oxoethyl)amino)acetic acid, an IDA analogue) has been synthesized and evaluated for in vitro imaging probes of β-amyloid (Aβ) aggregates.
Yang Yang   +3 more
doaj   +1 more source

Optimal clinical protocols for total-body 18F-FDG PET/CT examination under different activity administration plans

open access: yesEJNMMI Physics, 2023
Background Highly sensitive digital total-body PET/CT scanners (uEXPLORER) have great potential for clinical applications and fundamental research. Given their increasing sensitivity, low-dose scanning or snapshot imaging is now possible in clinics ...
Yanchao Huang   +10 more
doaj   +1 more source

The development and use of novel iridium complexes as catalysts for ortho-directed hydrogen isotope exchange reactions [PDF]

open access: yes, 2010
The preparation and application of groups of new iridium complexes are described. In particular, iridium complexes possessing phosphine ligands and a bulky N-heterocyclic carbene have been shown to be robust and readily handled species and have been ...
Atzrodt   +42 more
core   +1 more source

Nuclear medicine as a tool for diagnosis and targeted cancer therapy

open access: yesБюллетень сибирской медицины, 2018
The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide ...
V. I. Chernov   +5 more
doaj   +1 more source

What is the Potential Impact of the IsoDAR Cyclotron on Radioisotope Production: A Review [PDF]

open access: yesEJNMMI Radiopharmacy and Chemistry 5:6 (2020), 2018
The IsoDAR collaboration is developing a high-current cyclotron for a neutrino search experiment. Designed to deliver 10 mA of 60 MeV protons, the current and power of this cyclotron far exceed those of existing accelerators, opening new possibilities for the production of radiopharmaceutical isotopes, producing very high-activity samples in very short
arxiv   +1 more source

Close contact restriction periods for patients who received iodine-131 therapy for differentiated thyroid cancer [PDF]

open access: yes, 2022
Objective. Patients treated with radionuclide therapy may require restrictions on certain activities for a period of time following treatment to optimise protection of the public and ensure the legal dose limit is not exceeded. Software may be used to calculate necessary restriction periods for an individual based on longitudinal dose rate measurements
arxiv   +1 more source

A Quantitative Proteomic Approach Explores the Possible Mechanisms by Which the Small Molecule Stemazole Promotes the Survival of Human Neural Stem Cells

open access: yesBrain Sciences, 2022
Neurodegenerative disorders have become a serious healthcare problem worldwide and there is no efficacious cure. However, regulating the fate of stem cells is an effective way to treat these neurological diseases. In previous work, stemazole was reported
Mingzhu Chen   +4 more
doaj   +1 more source

Application of chiral 2-isoxazoline for the synthesis of syn-1,3-diol analogs

open access: yesBeilstein Journal of Organic Chemistry, 2019
The asymmetric cycloaddition of TIPS nitronate catalyzed by “Cu(II)-bisoxazoline” gave the 2-isoxazoline product in 95% yield, which was converted into tert-butyl (3S,5R)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate in 14 steps through a β ...
Juanjuan Feng   +3 more
doaj   +1 more source

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