Results 41 to 50 of about 51,772 (325)
Role of AI in Theranostics: Towards Routine Personalized Radiopharmaceutical Therapies [PDF]
We highlight emerging uses of artificial intelligence (AI) in the field of theranostics, focusing on its significant potential to enable routine and reliable personalization of radiopharmaceutical therapies (RPTs). Personalized RPTs require patient-individual dosimetry calculations accompanying therapy.
arxiv
Immunoscintigraphy for therapy decision making and follow-up of biological therapies [PDF]
With the availability of new biological therapies there is the need of more accurate diagnostic tools to noninvasively assess the presence of their targets.
Auletta, S.+6 more
core +2 more sources
A neutral compound Re(CO)3(L) (L: 2-((2-(2,6-diethylphenylamino)-2-oxoethyl)(2-ethoxy-2-oxoethyl)amino)acetic acid, an IDA analogue) has been synthesized and evaluated for in vitro imaging probes of β-amyloid (Aβ) aggregates.
Yang Yang+3 more
doaj +1 more source
Background Highly sensitive digital total-body PET/CT scanners (uEXPLORER) have great potential for clinical applications and fundamental research. Given their increasing sensitivity, low-dose scanning or snapshot imaging is now possible in clinics ...
Yanchao Huang+10 more
doaj +1 more source
The development and use of novel iridium complexes as catalysts for ortho-directed hydrogen isotope exchange reactions [PDF]
The preparation and application of groups of new iridium complexes are described. In particular, iridium complexes possessing phosphine ligands and a bulky N-heterocyclic carbene have been shown to be robust and readily handled species and have been ...
Atzrodt+42 more
core +1 more source
Nuclear medicine as a tool for diagnosis and targeted cancer therapy
The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide ...
V. I. Chernov+5 more
doaj +1 more source
What is the Potential Impact of the IsoDAR Cyclotron on Radioisotope Production: A Review [PDF]
The IsoDAR collaboration is developing a high-current cyclotron for a neutrino search experiment. Designed to deliver 10 mA of 60 MeV protons, the current and power of this cyclotron far exceed those of existing accelerators, opening new possibilities for the production of radiopharmaceutical isotopes, producing very high-activity samples in very short
arxiv +1 more source
Close contact restriction periods for patients who received iodine-131 therapy for differentiated thyroid cancer [PDF]
Objective. Patients treated with radionuclide therapy may require restrictions on certain activities for a period of time following treatment to optimise protection of the public and ensure the legal dose limit is not exceeded. Software may be used to calculate necessary restriction periods for an individual based on longitudinal dose rate measurements
arxiv +1 more source
Neurodegenerative disorders have become a serious healthcare problem worldwide and there is no efficacious cure. However, regulating the fate of stem cells is an effective way to treat these neurological diseases. In previous work, stemazole was reported
Mingzhu Chen+4 more
doaj +1 more source
Application of chiral 2-isoxazoline for the synthesis of syn-1,3-diol analogs
The asymmetric cycloaddition of TIPS nitronate catalyzed by “Cu(II)-bisoxazoline” gave the 2-isoxazoline product in 95% yield, which was converted into tert-butyl (3S,5R)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate in 14 steps through a β ...
Juanjuan Feng+3 more
doaj +1 more source