Results 41 to 50 of about 78,818 (344)

Ginsenoside Rb1 can ameliorate the key inflammatory cytokines TNF-α and IL-6 in a cancer cachexia mouse model

BMC Complementary Medicine and Therapies, 2020
Background Cancer cachexia is a severe condition that leads to the death of advanced cancer patients, and approximately 50~80% of cancer patients have cancer cachexia.
Shuai Lu, Yubo Zhang, Huajun Li, Jing Zhang, Yingqian Ci, Mei Han   +5 more
doaj   +1 more source

Immunoscintigraphy for therapy decision making and follow-up of biological therapies [PDF]

, 2016
With the availability of new biological therapies there is the need of more accurate diagnostic tools to noninvasively assess the presence of their targets.
Auletta, S., Carideo, Luciano, Galli, Filippo, Lauri, Chiara, Pacilio, Massimiliano, Signore, Alberto, Valabrega, Stefano   +6 more
core   +2 more sources

Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Pharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan, Yitong Liu, Lihao Liao, Jinyu Hao, Yuhao Jiang, Jianyong Jiang, Junbo Zhang   +6 more
doaj   +1 more source

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

Zhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Internal radiation dose assessment of radiopharmaceuticals prepared with cyclotron-produced 99m Tc [PDF]

, 2019
Technetium-99m (99m Tc) is the radioisotope most widely used in diagnostic nuclear medicine. It is readily available from 99 Mo/99m Tc generators as the \u3b2- decay product of the 99 Mo (T\ubd =66 h) parent nuclide.
Bello, Michele, De Nardo, Laura, Esposito, Juan, Ferro-Flores, Guillermina, Mel\ue9ndez-Alafort, Laura, Negri, Anna, Paiusco, Marta, Rosato, Antonio, Uzunov, Nikolay, Zorz, Alessandra   +9 more
core   +1 more source

Current status and future perspective of radiopharmaceuticals in China

European Journal of Nuclear Medicine and Molecular Imaging, 2021
Radiopharmaceuticals are essential components of nuclear medicine and serve as one of the cornerstones of molecular imaging and precision medicine. They provide new means and approaches for early diagnosis and treatment of diseases.
Ji Hu, Hongyu Li, Yanying Sui, Jin Du
semanticscholar   +1 more source

Imaging infection and inflammation [PDF]

, 2015
No abstract ...
A. W., Glaudemans, F., Rouzet, Galli, Filippo, Signore, Alberto   +3 more
core   +1 more source

One‐Step Assembly of α‐Aryl‐Substituted DOTAs as Superior and Universal Platforms for Multifunctional Theranostics

Angewandte Chemie, EarlyView.
A one‐step multi‐component synthetic approach is reported to construct α‐aryl‐substituted DOTAs, which required tedious multi‐step synthesis in all previous works. The synthesized α‐aryl‐substituted DOTAs showed improved performance for developing multifunctional theranostics and represent a universal platform for bioconjugation. Abstract α‐Substituted
Pak‐Lun Lam, Yue Wu, Lijia Yao, Hei‐Yui Kai, Ho‐Fai Chau, Qian Zhang, Wanqi Zhou, Jean‐Claude G. Bünzli, Ka‐Leung Wong   +8 more
wiley   +2 more sources

Methods to Enhance the Metabolic Stability of Peptide-Based PET Radiopharmaceuticals

Molecules, 2020
The high affinity and specificity of peptides towards biological targets, in addition to their favorable pharmacological properties, has encouraged the development of many peptide-based pharmaceuticals, including peptide-based positron emission ...
Brendan J Evans, Andrew T King, A. Katsifis, L. Matesic, J. Jamie   +4 more
semanticscholar   +1 more source

Radioisotopic purity and imaging properties of cyclotron-produced 99mTc using direct 100Mo(p,2n) reaction [PDF]

, 2018
Evaluation of the radioisotopic purity of technetium-99m (99mTc) produced in GBq amounts by proton bombardment of enriched molibdenum-100 (100Mo) metallic targets at low proton energies (i.e. within 15\u201320 MeV) is conducted.
Bello, M., Boschi, A., Cicoria, G., De Nardo, L., Di Domenico, G., Duatti, A., Esposito, J., Groppi, F., Loriggiola, M., Manenti, S., Marengo, M., Martini, P., Melendez-Alafort, L., Mou, L., Pasquali, M., Pupillo, G., Rosato, A., Rossi-Alvarez, C., Salvini, A., Selva, A., Strada, L., Taibi, A., Uccelli, L., Uzunov, N. M., Zagni, F.   +24 more
core   +2 more sources