Results 141 to 150 of about 26,475 (236)

FGFR1 Induces Glioblastoma Radioresistance through the PLC /Hif1  Pathway

, 2016
International audienceAbstract FGF2 signaling in glioblastoma induces resistance to radiotherapy, so targeting FGF2/FGFR pathways might offer a rational strategy for tumor radiosensitization.
V. Gouaze-Andersson, S. Evrard, C. Toulas, Mazoyer, Sandrine, S. Mazoyer, J. Martinez-Gala, M. Taurand, Martinez-Gala, Judith, Toulas, Christine, Taurand, Marion, Cohen-Jonathan-Moyal, Elizabeth, Delmas, Caroline, E. Cohen-Jonathan-Moyal, Gouazé-Andersson, Valérie, Evrard, Solène, C. Delmas   +15 more
core   +1 more source

Combining decitabine with radiotherapy to enhance nasopharyngeal carcinoma radiosensitivity via the TFAP2C-OTUD1-SLC25A11 axis

Cell Death and Disease
Nasopharyngeal carcinoma (NPC) is a common malignancy in certain geographic regions, with radiotherapy serving as the primary treatment. Recent research shows that epigenetics and deubiquitinases (DUBs) are crucial in NPC progression and treatment ...
Haixia Zhang, Siyang Liu, Dan Wang, Yaqi Liao, Shizhen Li, Jing He, Jie Shen, Lu Yan, Tengfei Xiao, Wangning Gu, Hongmin Yang, Hui Wang, Minghua Yang, Pan Chen   +13 more
doaj   +1 more source

ACSS1 co-opts acetyl-CoA metabolism to drive DNA repair and undermine radiotherapy efficacy in breast cancer

Cell Death and Disease
Breast cancer remains a leading cause of cancer-related mortality worldwide, with radiotherapy serving as a cornerstone of treatment. However, the development of radioresistance significantly compromises therapeutic efficacy and patient outcomes. Through
Xiao Fu, Yingyu Zhu, Xin Lu, Xingjie Gao, Lingbiao Xin, Yuanyuan Ren, Xin Liu, Lin Ge, Jihui Hao, Zhi Yao, Lei Shi, Jie Yang   +11 more
doaj   +1 more source

Overcoming Cancer Radioresistance Factors of radioresistance in prostate cancer

Radiotherapy and Oncology, 2016
Krause, M., Dubrovska, A., Baumann, M.
openaire   +1 more source

High-Glucose Environment Promotes Radioresistance in Colorectal Cancer via SERPINE1-Enhanced DNA Repair and Anti-Apoptosis. [PDF]

Int J Med Sci
Ke CC, Zhang YC, Wang PJ, Wang CY, Kuo SH, Li CY, Huang MY, Hsieh YJ.   +7 more
europepmc   +1 more source

Molecular mechanisms of m6A modifications regulating tumor radioresistance

Radiotherapy is one of the most effective treatments for malignant tumors. Radioresistance is a major factor that contributes to radiotherapy failure and poor prognosis. Recent studies have elucidated the pivotal role of aberrant N6-methyladenosine (m6A)
Ruolin Shen, Zhenyang Jiang, Xin Jiang, Zhuangzhuang Zheng, Huanhuan Wang   +4 more
core   +1 more source

Decoding the role of non-coding RNAs in HNSCC radioresistance: molecular mechanisms and clinical implications. [PDF]

Front Oncol
Ge FX, Yang H, Wang XZ, Liu ZH, Shao D, Liu HX.   +5 more
europepmc   +1 more source

Targeting adaptive radioresistance in glioblastoma

Neuro-Oncology, 2022
openaire   +2 more sources

A three-gene radioresistance signature predicts tumor progression in cervical cancer. [PDF]

Transl Cancer Res
Yu H, Xiu Y, Meng F, He H, Wang Y, Liu T, Wang Z, Wang Z, Zhao K, Wang Y, Chen Z, Sun B.   +11 more
europepmc   +1 more source

The mechanism of breast cancer stem cells and tumor microenvironment promoting radioresistance in breast cancer and its intervention strategies. [PDF]

Front Immunol
Zhao Y, Liu X, Bai X, Tang J.
europepmc   +1 more source