Results 11 to 20 of about 14,471 (229)
Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers
Translational Oncology, 2015 In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes.
Dongping Wei +9 more
doaj +2 more sources
Progression in low‐intensity ultrasound‐induced tumor radiosensitization
Cancer MedicineBackground Radiotherapy (RT) is a widely utilized tumor treatment approach, while a significant obstacle in this treatment modality is the radioresistance exhibited by tumor cells.
Haonan Xu +3 more
doaj +2 more sources
Vemurafenib and Radiosensitization [PDF]
JAMA Dermatology, 2013 The BRAF inhibitor, vemurafenib, was recently approved for the treatment of patients with BRAFV600 metastatic melanoma. Wider use of this drug and longer follow-up periods of treatment are resulting in the emergence of a growing number of reports detailing new adverse effects.
Lise, Boussemart +8 more
openaire +2 more sources
Surface-ligand effect on radiosensitization of ultrasmall luminescent gold nanoparticles [PDF]
Journal of Innovative Optical Health Sciences, 2016 Gold nanoparticles (AuNPs) could serve as potential radiotherapy sensitizers because of their exceptional biocompatibility and high-Z material nature; however, since in vitro and in vivo behaviors of AuNPs are determined not only by their particle size ...
Xingya Jiang +4 more
doaj +1 more source
The Effects of p53 and p53R2 Expression on Gemcitabine-Mediated Cytotoxicity and Radiosensitization. [PDF]
Gemcitabine (dFdCyd) is a nucleoside analog that produces synergistic killing of tumor cells with ionizing radiation (radiosensitization). Previously, radiosensitization correlated with dATP depletion, mediated by dFdCyd diphosphate inhibition of ...
Barber, Joe
core +4 more sources
Radiosensitization and apoptosis [PDF]
Oncogene, 1998 The toxicity of radiation to living tissues was discovered soon after the discovery of radioactivity itself and this toxicity is the basis for cancer therapy with radiation. Although this mode of therapy is often effective, its success is far from assured.
R J, Muschel +3 more
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BMC Chemistry, 2023 Nanoparticle-based composites have the potential to meet requirements for radiosensitization in both therapeutic and diagnostic applications. The radiosensitizing properties of nanoparticles could be reliant on the nature of their coating layer.
Elham Mansouri +5 more
doaj +1 more source
Frontiers in Oncology, 2021 Significant opportunities remain for pharmacologically enhancing the clinical effectiveness of proton and carbon ion-based radiotherapies to achieve both tumor cell radiosensitization and normal tissue radioprotection.
Alicia M. Johnson +8 more
doaj +1 more source
Radiosensitizing Nucleosides [PDF]
JNCI Journal of the National Cancer Institute, 1996 Chemotherapeutic drugs that perturb nucleotide metabolism have the potential to produce substantial sensitization of tumor cells to radiation treatment. The process is called radiosensitization, and the agents that induce it are called radiosensitizers.
C J, McGinn, D S, Shewach, T S, Lawrence
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Dose-Response, 2022 Objective To study the radiosensitization effect of curcumin, a natural product with anti-inflammatory and anti-cancer properties, in bladder cancer cells and identify the specific role of FLNA gene in that process.
Zhenfan Wang +4 more
doaj +1 more source