Results 71 to 80 of about 9,097 (242)

Novel Cerium- and Terbium-Doped Gadolinium Fluoride Nanoparticles as Radiosensitizers with Pronounced Radiocatalytic Activity

Biomedicines
Background: The use of nanoradiosensitizers is a promising strategy for the precision enhancement of tumor tissue damage during radiotherapy. Methods: Here, we propose a novel biocompatible theranostic agent based on gadolinium fluoride doped with cerium
Nikita A. Pivovarov, Danil D. Kolmanovich, Nikita N. Chukavin, Irina V. Savintseva, Nelli R. Popova, Alexander E. Shemyakov, Arina D. Filippova, Maria A. Teplonogova, Alexandra V. Yurkovskaya, Ivan. V. Zhukov, Azamat Y. Akkizov, Anton L. Popov   +11 more
doaj   +1 more source

Silica-coated bismuth ferrite nanoparticles as novel radiosensitizers for cancer radiotherapy [PDF]

Nanomedicine Journal
Objective(s): Radiotherapy is a cornerstone of cancer treatment; however, tumor radioresistance remains a major limitation. The use of radiosensitizers offers a strategy to selectively enhance the sensitivity of malignant cells to ionizing radiation ...
Nasim Kavousi, mohammad taghi Bahreyni Toosi, Hosein Azimian, Mona Alibolandi   +3 more
doaj   +1 more source

Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy

, 2022
Background: Glioblastoma is the most lethal primary brain malignancy in adults. Standard of care treatment, consisting of temozolomide (TMZ) and adjuvant radiotherapy (RT), mostly does not prevent local recurrence.
Tamar Sadan, Sadan, Tamar, Menachem Motiei, Friedmann-Morvinski, Dinorah, Nikitin, Maxim, Rachela Popovtzer, Betzer, Oshra, Omer Gal, Popovtzer, Rachela, Maxim Nikitin, Liat Rousso-Noori, Popovtzer, Aron, Rousso-Noori, Liat, Aron Popovtzer, Gal, Omer, Motiei, Menachem, Dinorah Friedmann-Morvinski, Oshra Betzer   +17 more
core   +1 more source

The radiosensitivity of rat thymocytes [PDF]

Biochemical Journal, 1986
gamma-Irradiation in vitro apparently blocked a plasma-membrane associated, superoxide-producing, NADPH oxidase in rat thymocytes. Differential centrifugation of the mixed thymocytes indicated the smaller lymphocytes (approx. 6 microns diameter) to be the radiosensitive population.
M G, Ord, L A, Stocken
openaire   +2 more sources

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Radiotherapy quality assurance of the IAEA-HypoX trial of the accelerated radiotherapy in the treatment of head and neck squamous cell carcinoma with or without the hypoxic radiosensitizer nimorazole

, 2015
Radiotherapy quality assurance of the IAEA-HypoX trial of the accelerated radiotherapy in the treatment of head and neck squamous cell carcinoma with or without the hypoxic radiosensitizer ...
Primoz Strojan (810578), Jens Overgaard (48654), Tarek Shouman (810577), Rubina Ali (810575), Cai Grau (810579), Maire Kuddu (810576), Mohamed A. Hassan Metwally (810574)   +6 more
core   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

The role of propranolol as a radiosensitizer in gastric cancer treatment

, 2018
Xinhua Liao, Prakash Chaudhary, Guanglin Qiu, Xiangming Che, Lin Fan General Surgery Department, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China Purpose: The National Comprehensive Cancer Network guidelines ...
Chaudhary P, Qiu G, Liao XH, Fan L, Che XM   +4 more
core  

Folate-Targeted Polymeric Nanoparticle Formulation of Docetaxel Is an Effective Molecularly Targeted Radiosensitizer with Efficacy Dependent on the Timing of Radiotherapy

, 2016
Nanoparticle (NP) chemotherapeutics hold great potential as radiosensitizers. Their unique properties, such as preferential accumulation in tumors and their ability to target tumors through molecular targeting ligands, are ideally suited for ...
Michael E. Werner (2144761), Rohit Sukumar (2144764), Jonathan A. Copp (1314732), Shrirang Karve (2144773), Natalie D. Cummings (2144767), Chenxi Li (1459123), Adrienne D. Cox (586195), Andrew Z. Wang (730388), Mary E. Napier (1836016), Ronald C. Chen (2144770)   +9 more
core   +1 more source