Results 81 to 90 of about 27,469 (292)
The Biofunctional Effects of Mesima as a Radiosensitizer for Hepatocellular Carcinoma
International Journal of Molecular Sciences, 2020 The tropical basidiomycete fungus Phellinus linteus (Mesima) exhibits anti-tumor, anti-angiogenic, and immunomodulatory properties in various cancers including prostate, colon, and lung cancer along with melanoma by, for example, inducing apoptosis or ...
Youn Kyoung Jeong +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Advances in Gold Nanoparticle-Based Combined Cancer Therapy
Nanomaterials, 2020 According to the global cancer observatory (GLOBOCAN), there are approximately 18 million new cancer cases per year worldwide. Cancer therapies are largely limited to surgery, radiotherapy, and chemotherapy.
Kyle Bromma, Devika B. Chithrani
doaj +1 more source
Applied Sciences, 2023 This study aims to evaluate the dependence of DNA damage on the proportion of iron and gold in iron-gold nanoparticle heterojunctions using Monte Carlo simulations.
James C. L. Chow, Christine A. Santiago
doaj +1 more source
The effect of HIV and antiretroviral therapy on chromosomal radiosensitivity [PDF]
, 2015 Introduction: Antiretroviral Treatment (ART) has led to an improvement in survival of HIV infected individuals. Some of them will develop cancer during the course of their infection and will require radiation therapy.
Baeyens, Ans +3 more
core +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Oral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small cell lung cancer (NSCLC): A feasibility study [PDF]
, 2006 Background: Concurrent chemoradiotherapy has improved survival in inoperable stage III non-small cell lung cancer (NSCLC). This phase I trial was performed in order to establish a dose recommendation for oral vinorelbine in combination with cisplatin and
Clamon G +17 more
core +1 more source
Radiosensitization and apoptosis [PDF]
Oncogene, 1998 The toxicity of radiation to living tissues was discovered soon after the discovery of radioactivity itself and this toxicity is the basis for cancer therapy with radiation. Although this mode of therapy is often effective, its success is far from assured.
R J, Muschel +3 more
openaire +2 more sources
Advanced Science, EarlyView.Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren +12 more
wiley +1 more source