Evaluation of a Rhenium(I) Complex and Its Pyridostatin-Containing Chelator as Radiosensitizers for Chemoradiotherapy [PDF]
MoleculesThe use of radiosensitizers is a beneficial approach in cancer radiotherapy treatment. However, the enhancement of radiation effects on cancer cells by radiosensitizers involves several different mechanisms, reflecting the chemical nature of the ...
Ana Belchior +2 more
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Hybrid Biomaterials-Based Radiosensitizers: Preparations and Their Applications in Enhancing Tumor Radiotherapy [PDF]
Materials Today BioRadiotherapy is a critical modality in cancer treatment, yet its efficacy can be substantially hindered by the tumor microenvironment. Nanotechnology has empowered nanomaterials to assume multifunctional roles.
Wenjing Xiao, Qinrui Fu
exaly +4 more sources
Hypoxia-Targeting Strategies in Radiotherapy and Nitroimidazole-Based Radiosensitizers: A Narrative Review and Translational Perspectives [PDF]
Current Issues in Molecular BiologyBackground: Tumor hypoxia is a major determinant of radioresistance, limiting oxygen-mediated fixation of radiation-induced DNA damage and promoting metabolic adaptation, tumor aggressiveness, and treatment failure. Nitroimidazole derivatives and related
Enrico Rosa +9 more
doaj +2 more sources
Application of Radiosensitizers in Cancer Radiotherapy
International Journal of Nanomedicine, 2021 Liuyun Gong,1 Yujie Zhang,2,3 Chengcheng Liu,2 Mingzhen Zhang,2,3 Suxia Han1 1Department of Oncology, The First Affiliated Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710061, People’s Republic of China; 2School of Basic Medical
Mingzhen Zhang, Liuyun Gong, Suxia Han
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Application of Nano-Radiosensitizers in Combination Cancer Therapy
Bioengineering and Translational Medicine, 2023 Radiosensitizers are compounds or nanostructures, which can improve the efficiency of ionizing radiation to kill cells. Radiosensitization increases the susceptibility of cancer cells to radiation‐induced killing, while simultaneously reducing the ...
Michael R. Hamblin +2 more
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Golden Era of Radiosensitizers
Frontiers in Veterinary ScienceThe past 30 years have brought undeniable progress in medicine, biology, physics, and research. Knowledge of the nature of the human body, diseases, and disorders has been constantly improving, and the same is true regarding their treatment and diagnosis.
Vít Blanař +2 more
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Biogenic ZnO-CuO Nanocomposites Synthesised Using Salvia africana Luteus Increased the Radiosensitising Effect of Proton Irradiation in MCF7 Breast Cancer Cells [PDF]
NanomaterialsRadiation therapy is widely used for cancer treatment. To improve therapeutic efficacy, traditional radiosensitizers are often used in combination.
Kunle Okaiyeto +4 more
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Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy [PDF]
Advanced ScienceRadiotherapy (RT) is a mainstay therapeutic strategy for cancer; however, increasing radiation damage to tumor tissues while reducing the side effects on healthy tissues remains a great challenge. To address this issue, the use of biomaterials has proven
Qian Wang, Xinhui Chu, Jianfeng Liu
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Targeting the Enhanced Sensitivity of Radiotherapy in Cancer: Mechanisms, Applications, and Challenges [PDF]
MedCommCancer is a major public health, societal, and economic challenge worldwide. According to Global Cancer Statistics 2022, it is estimated that by 2050, there will be 35 million new cancer cases globally.
Yuanyuan Zhao +5 more
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Fe/57Fe-Metallacarboranes with Radiosensitizing Potential in Breast Cancer Cell Models: Comparative Study Between High- (60Co) and Low-Energy (57Co) Gamma Radiation Sources [PDF]
PharmaceuticsBackground: Radiosensitizers can be used to enhance tumor response and mitigate toxicity in healthy tissues during radiation therapy. This study investigates the radiosensitizing potential of the metallacarborane Fe/57Fe-ferrabisdicarbollide in SK-BR-3 ...
Salvatore Di Maria +12 more
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