Results 61 to 70 of about 75,672 (296)

Dosimetric Comparison between 6MV Flattened Filter and Flattening Filter Free Photon Beams in the Treatment of Glioblastoma with IMRT Technique: A Treatment Planning Study [PDF]

Iranian Journal of Medical Physics, 2020
Introduction: The present study evaluated the dosimetric comparison between 6MV flattened filter (FF) and flattening filter-free (FFF) photon beams in intensity-modulated radiation therapy (IMRT) technique for the treatment of glioblastoma (GBM) patients.
Dinesh Saroj, Suresh Yadav, Gopa Ghosh, Shuchishree Shukla, Gaurav Gupta, S. Choudhary   +5 more
doaj   +1 more source

Fraction-variant beam orientation optimization for non-coplanar IMRT

, 2017
Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously optimizes non ...
Nguyen, Dan, O'Connor, Daniel, Ruan, Dan, Sheng, Ke, Yu, Victoria   +4 more
core   +1 more source

A systematic review of methods to immobilise breast tissue during adjuvant breast irradiation [PDF]

, 2013
Greater use of 3D conformal, Intensity Modulated Radiotherapy (IMRT) and external beam partial breast irradiation following local excision (LE) for breast cancer has necessitated a review of the effectiveness of immobilisation methods to stabilise breast
Barrett-Lennard, Becker, Bentel, Bentzen, Canney, Carter, Centre for Reviews and Dissemination, Chen, Chopra, Christopher Bragg, Clarke, Creutzberg, Croog, Cross, David Dodwell, David Green, Fisher, Fisher, Fisher, Gierga, Goldsworthy, Graham, Grann, Hector, Heidi Probst, Hurkmans, Jagsi, John Hart, Keller, Kirby, Latimer, Mahe, Mitchell, Morrow, Munshi, Nalder, Office for National Statistics, Probst, Scottish Intercollegiate Guidelines Network, Stegman, Strydhorst, The Royal College of Radiologists, Institute of Physics and Engineering in Medicine, Society and College of Radiographers, Thilmann, Valdagni, Varga, Veldeman, Veldeman, Veronesi, Zierhut   +48 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Volumetric intensity-modulated Arc (RapidArc) therapy for primary hepatocellular carcinoma: comparison with intensity-modulated radiotherapy and 3-D conformal radiotherapy

Radiation Oncology, 2011
Background To compare the RapidArc plan for primary hepatocellular carcinoma (HCC) with 3-D conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) plans using dosimetric analysis.
Chen Chia-Wen, Yu Hsiao-Wei, Shih Wen-Pin, Chiu Ying-Ming, Kuo Yu-Cheng, Wong Pei-Fong, Lin Wei-Chan, Hwang Jeng-Jong   +7 more
doaj   +1 more source

Radiation Therapy Medical Physics Review – Delivery, Interactions, Safety, Feasibility, and Head to Head Comparisons of the Leading Radiation Therapy Techniques [PDF]

, 2017
Radiation therapy uses high energy radiation to kill cancer cells. Radiation therapy for cancer treatment can take the form of photon therapy (using x-rays and gamma rays), or charged particle therapy including proton therapy and electron therapy. Within
Collins, Cielle
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

GPU-based ultra-fast direct aperture optimization for online adaptive radiation therapy

, 2010
Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy.
Bazaraa M, Bentley J, Chunhua Men, Earl M A, Fox C, Gu X, Gu X, Hoberock J Bell N, Kokubo M, Langen K M, Li M, Li Y J, Men C, Men C, Steve B Jiang, Wong J R, Wu C, Wu Q J, Xing M Decaudin P Baogang H Xiaopeng Z, Xun Jia, Yan D, Zhang G W   +21 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source