Results 71 to 80 of about 9,194 (267)

CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases (CARBON): study protocol for a phase IB/IIA randomised controlled trial

open access: yesTrials, 2020
Background A substantial proportion of breast cancer patients develop metastatic disease, with over 450,000 deaths globally per year. Bone is the most common first site of metastatic disease accounting for 40% of all first recurrence and 70% of patients ...
Rob Coleman   +11 more
doaj   +1 more source

Alpha‐emitters and targeted alpha therapy in cancer treatment

open access: yesiRADIOLOGY, 2023
Alpha emitters are radionuclides with good pharmacological characteristics for the treatment of cancer because they decay by emitting high linear energy transfer particles.
Jiajia Zhang   +5 more
doaj   +1 more source

Radiopharmaceuticals in the elderly cancer patient: Practical considerations, with a focus on prostate cancer therapy: A position paper from the International Society of Geriatric Oncology Task Force. [PDF]

open access: yes, 2017
Molecular imaging using radiopharmaceuticals has a clear role in visualising the presence and extent of tumour at diagnosis and monitoring response to therapy. Such imaging provides prognostic and predictive information relevant to management, e.g.
Aapro, M.   +5 more
core   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Radium-223 for the treatment of patients with castration-resistant prostate cancer with bone metastases

open access: yesМедицинский совет, 2018
The development of resistance to endocrine therapy and the tumor progression in patients with prostate cancer are associated with an unfavourable prognosis.
A. D. Kaprin   +3 more
doaj   +1 more source

Recent Insights in Barium-131 as a Diagnostic Match for Radium-223: Cyclotron Production, Separation, Radiolabeling, and Imaging

open access: yesPharmaceuticals, 2020
Barium-131 is a single photon emission computed tomography (SPECT)-compatible radionuclide for nuclear medicine and a promising diagnostic match for radium-223/-224.
Falco Reissig   +8 more
doaj   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun   +4 more
wiley   +1 more source

Utility of F-18 FDG PET/CT for Detection of Bone Marrow Metastases in Prostate Cancer Patients Treated with Radium-223 [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2018
A 76-year-old man with symptomatic bone metastases from castrationresistant prostate cancer underwent Radium-223-dichloride (Ra-223) therapy. Before Ra-223 therapy, he had normal peripheral blood cell counts.
Kaoru Maruyama   +5 more
doaj   +1 more source

Impact of skeletal-related events on survival in patients with metastatic prostate cancer prescribed androgen deprivation therapy [PDF]

open access: yes, 2016
published_or_final_versio
Ho, KL   +7 more
core   +1 more source

Advances in Triboelectric Nanogenerators With Rotating Structure

open access: yesCarbon Energy, EarlyView.
The rotating TENG has been widely studied for its superiorities of simple structure, high efficiency, and stable output. This review introduced the four different principles of rotating TENG and offered a thorough summary for performance and application research through three‐level classification. Importantly, the current existing problems, challenges,
Chuguo Zhang   +4 more
wiley   +1 more source

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