Results 51 to 60 of about 14,947 (171)

AIE‐Mediated In Situ Monitoring of Protein Aggregates During Coagulation and Screening of Anticoagulant Agents

open access: yesAggregate, Volume 7, Issue 1, January 2026.
The process of screening active monomers via BioSTAS technology. (A) Analyzing the properties and luminescence mechanism of an AIE molecule through density functional theory and MD simulation. (B) The establishment of a screening model, including biosensing and affinity chromatography. (C) Screening and identification of active substances.
Shuxian Zhang   +12 more
wiley   +1 more source

Effect of Polygala radix Hot Water Extract on Biological Activity in PC12 Cells [PDF]

open access: yesJournal of Life Science, 2013
The root of Polygala radix has been widely known as an oriental traditional medicinal stuff that improves memory. However, its mechanism of action remains unclear. In this study, the effect of Polygala radix hot water extracts (PRHWE) on cognitive function related to the activity of acetylcholinesterase (AchE) derived from neural cells (PC12) in ...
Hyang Nam, Moon-Moo Kim
openaire   +1 more source

aiunderstand/tt03p5-4-trit-balanced-ternary-counter-bt_signb_bt-radix-convertor: Submitted for tapeout

open access: yes, 2023
A 4-trit balanced ternary counter and 3-trit BT to signed binary to BT radix convertor for TinyTapeout 3.5 made with ...
Steven Bos
core   +1 more source

Therapeutic Potential of Irpex lacteus Polysaccharides in Lupus Nephritis: Insights From Gut Microbiota and Metabolomics Analysis in MRL/Lpr Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Polysaccharides from Irpex lacteus alleviated kidney inflammatory response. PCP could reverse the phenotype of MRL/lpr mice, reduce autoantibody levels, alleviate inflammatory responses, and improve renal function. Improving the body's metabolism by gut microbes may be the possible mechanism of PCP in treating LN.
Guoxin Ji   +9 more
wiley   +1 more source

Exploring natural products for insomnia: Effective solutions for better sleep

open access: yesSleep Research, Volume 2, Issue 3, Page 145-165, September 2025.
Abstract Insomnia, affecting millions worldwide, is a prevalent sleep disorder characterized by persistent difficulties in both initiating and maintaining sleep, leading to compromised daytime functioning, heightened risks of cardiovascular and psychiatric comorbidities, and substantial socioeconomic burdens necessitating the pursuit of safer and more ...
Yingjie Cai   +5 more
wiley   +1 more source

Traditional Chinese Medicine for Senile Dementia [PDF]

open access: yes, 2012
Traditional Chinese Medicine (TCM) has a 3000 years' history of human use. A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients includingPoria cocos,Radix polygalae,Radix ...
Zhihong Lin   +5 more
core   +1 more source

Antidepressant-like effect of Radix Polygalae in mouse models of behavioral despair and hedonism.

open access: yes, 2014
(A) Immobility in tail suspension test measured 30 minutes after RP (0.1, 1 and 10 mg/kg p.o.). There was a significant dose effect [F(3,31) = 5.62, p = 0.0038].
Sung Un Son (521287)   +12 more
core   +1 more source

Protective effects of Bushen Tiansui decoction on hippocampal synapses in a rat model of Alzheimer's disease

open access: yesNeural Regeneration Research, 2017
Bushen Tiansui decoction is composed of six traditional Chinese medicines: Herba Epimedii, Radix Polygoni multiflori, Plastrum testudinis, Fossilia Ossis Mastodi, Radix Polygalae, and Rhizoma Acorus tatarinowii.
Shan Hui   +7 more
doaj   +1 more source

Putative Identification of 47 Compounds from Jieyu Anshen Granule and Proposal of Pharmacopeia Quality‐Assessment Strategy Using TCM‐Specific Library with UHPLC‐Q‐Exactive‐Orbitrap‐MS

open access: yesChemistryOpen, Volume 14, Issue 1, January 2025.
Traditional Chinese medicine prescription Jieyu Anshen Granule is analyzed using UHPLC−Q‐Exactive Orbitrap‐MS/MS. Forty‐seven compounds are identified and 12 compounds are found in the Granule for the first time. Five compounds are proposed as Pharmacopeia quality‐markers.
Xican Li   +7 more
wiley   +1 more source

Alzheimer's disease drug development pipeline: 2024

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 10, Issue 2, April‐June 2024.
Abstract INTRODUCTION New therapies to prevent or delay the onset of symptoms, slow progression, or improve cognitive and behavioral symptoms of Alzheimer's disease (AD) are needed. METHODS We interrogated clinicaltrials.gov including all clinical trials assessing pharmaceutical therapies for AD active in on January 1, 2024.
Jeffrey Cummings   +5 more
wiley   +1 more source

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