Results 31 to 40 of about 14,947 (171)

Chinese herbal medicine combined with cognitive–behavioural therapy for avoidant paruresis: a controlled trial

General Psychiatry, Volume 36, Issue 5, October 2023., 2023
Background Avoidant paruresis is a common clinical condition in urology and psychosomatic medicine. However, it has limited treatment options that are safe and effective with few side effects. Aims Our study aimed to investigate the effectiveness and safety of the Chinese herbal Yangxin Tongquan decoction combined with cognitive–behavioural therapy ...
Shijie Liang, Ying Zhou, Chao Yu, Xiang Gao, Fangbin Ji, Qianyuan Fang, Zhihang Zhang, Libin Yang, Youkang Zhao, Yuhui Zhao, Renwu Yin, Kaimin Chen, Zheng Lu   +12 more
wiley   +1 more source

New insight of complement system in the process of vascular calcification

Journal of Cellular and Molecular Medicine, Volume 27, Issue 9, Page 1168-1178, May 2023., 2023
Abstract The complement system defences against pathogenic microbes and modulates immune homeostasis by interacting with the innate and adaptive immune systems. Dysregulation, impairment or inadvertent activation of complement system contributes to the pathogenesis of some autoimmune diseases and cardiovascular diseases (CVD). Vascular calcification is
Aiting Liu, Pei Luo, Hui Huang
wiley   +1 more source

Traditional Chinese medicine Jia Wei Gui Pi Tang improves behavioural and psychological symptoms of dementia and favourable positive emotions in patients

Psychogeriatrics, Volume 23, Issue 3, Page 503-511, May 2023., 2023
Background Behavioural and psychological symptoms of dementia (BPSD) are challenging to manage, leading to caregiver burden and often to subsequent transfer of patients to a nursing home or psychiatric hospital for treatment. Eliciting favourable positive emotions should be an important goal in the treatment of negative emotions associated with BPSD ...
Tatsuya Nogami, Koh Iwasaki, Hideo Kimura, Toru Higashi, Makoto Arai, James P. Butler, Masahiko Fujii, Hidetada Sasaki   +7 more
wiley   +1 more source

Alzheimer's disease drug development pipeline: 2023

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 9, Issue 2, April‐June 2023., 2023
Abstract Introduction Drugs that prevent the onset, slow progression, or improve cognitive and behavioral symptoms of Alzheimer's disease (AD) are needed. Methods We searched ClinicalTrials.gov for all current Phase 1, 2 and 3 clinical trials for AD and mild cognitive impairment (MCI) attributed to AD.
Jeffrey Cummings, Yadi Zhou, Garam Lee, Kate Zhong, Jorge Fonseca, Feixiong Cheng   +5 more
wiley   +1 more source

Preparation and Evaluation of Onjisaponin B‐Loaded Liposomes for Drug Delivery to Enhance Mitochondrial Function and Rescue Parkinson’s Disease by Activating Mitophagy

Journal of Clinical Pharmacy and Therapeutics, Volume 2023, Issue 1, 2023., 2023
Onjisaponin B (OB) is the main active ingredient of Radix Polygalae with various bioactivities. However, the protective effect of OB in Parkinson’s disease (PD) has not been fully studied. Liposomes are ideal nanocarriers for drugs targeting the brain. In this study, we investigated the therapeutic effect of OB‐loaded liposomes (lip OB) on a 1‐methyl‐4‐
Junhua Zhang, Rui Bao, Faisal Raza, Hajra Zafar, Yingjie Qi, Yurui Geng, Ran Li, Jianqin Xue, Feng Shi, Samuel Silvestre   +9 more
wiley   +1 more source

Ninjinyoeito Prevents Onset of Depression‐Like Behavior and Reduces Hippocampal iNOS Expression in Senescence‐Accelerated Mouse Prone 8 Mice

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Late‐life depression is a globally prevalent disorder. Ninjinyoeito (NYT), a traditional Japanese herbal medicine, attenuates depressive symptoms in older patients. However, the mechanisms underlying the antidepressive effect of NYT are unknown. In this study, we investigated the mechanism of the action of NYT using senescence‐accelerated mouse prone 8
Chise Taniguchi, Takuya Watanabe, Marika Hirata, Akinobu Hatae, Kaori Kubota, Shutaro Katsurabayashi, Katsunori Iwasaki, Teh Lay Kek   +7 more
wiley   +1 more source

Efficacy of Kami Guibi‐tang as an Add‐On Therapy to Acetylcholinesterase Inhibitor for Cognitive Function in Mild Alzheimer’s Disease: A Pilot Study

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Background. Kami Guibi‐tang (KGT), a traditional Korean herbal medicine is mainly used to treat insomnia and nervousness. Acetylcholinesterase inhibitors (AChEIs) are the main treatments for mild Alzheimer’s disease (AD), a degenerative brain disease. However, currently no drug can fundamentally treat AD or reverse the advanced cognitive decline.
Ha-Ri Kim, Hee-Yeon Shin, Tae-Bin Yim, Geon-Ho Jahng, Chul Jin, Seungwon Kwon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Chang-Nam Ko, Jung-Mi Park, Krishnadas Nandakumar   +12 more
wiley   +1 more source

Research Progress of the Liver–Brain Cotreatment of Depression with Supplemented Danzhi Xiaoyao Powder

Chinese Medicine and Natural Products, 2022
Traditional Chinese medicine (TCM) has unique advantages in preventing and treating depression based on holistic concepts and syndrome differentiation and treatment. Liver depression and spleen deficiency are the main syndrome of depression.
Yajing Li, Baoying Wang, Yucheng Li, Ming Bai, Erping Xu   +4 more
doaj   +1 more source

Kai-xin-san, a Chinese herbal decoction containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, stimulates the expression and secretion of neurotrophic factors in cultured astrocytes [PDF]

, 2013
Kai-xin-san (KXS), a Chinese herbal decoction prescribed by Sun Simiao in Beiji Qianjin Yaofang about 1400 years ago, contains Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria.
Tsim, Karl Wah Keung, Zhu, Kevin Yue, Choi, Roy Chi Yan, Yan, Artemis Lu, Dong, Tina Ting Xia, Xu, Sherry Li   +5 more
core   +1 more source

Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation

Neural Regeneration Research, 2017
Kai Xin San is a Chinese herbal formula composed of Radix Ginseng , Poria , Radix Polygalae and Acorus Tatarinowii Rhizome . It has been used in China for many years for treating amnesia.
Na Wang, Yong-ming Jia, Bo Zhang, Di Xue, Maharjan Reeju, Yan Li, Shu-ming Huang, Xue-wei Liu   +7 more
doaj   +1 more source