Results 41 to 50 of about 498,772 (347)

Brane Inflation from Rotation of D4 Brane [PDF]

, 2003
In this paper, a inflationary model from the rotation of D4-brane is constructed. We show that for a very wide rage of parameter, this model satisfies the observation and find that regarded as inflaton, the rotation of branes may be more nature than the ...
Arfaei H., Burgess C. P., Garcia-Bellido J., Garcia-Bellido J., Xinmin Zhang, Yuan-Zhong Zhang, Yun-Song Piao   +6 more
core   +1 more source

Involvement of RAGE and Oxidative Stress in Inflammatory and Infectious Skin Diseases

Antioxidants, 2021
The surface receptor for advanced glycosylation end-products (RAGE) and its soluble (sRAGE) and endogenous secretory (EN-RAGE) forms belong to the superfamily of toll-like receptors and play important roles in inflammation and autoimmunity, directly or ...
F. Guarneri, P. Custurone, Valeria Papaianni, S. Gangemi   +3 more
semanticscholar   +1 more source

Inhibition of RAGE signaling through the intracellular delivery of inhibitor peptides by PEI cationization [PDF]

, 2013
The receptor for advanced glycation end products (RAGE) is a multi-ligand cell surface receptor and a member of the immunoglobulin superfamily. RAGE is involved in a wide range of inflammatory, degenerative and hyper-proliferative disorders which span ...
Futami, Jun-Ichiro, Huh, Nam-Ho, Kataoka, Ken, Murata, Hitoshi, Putranto, Endy Widya, Sakaguchi, Masakiyo, Yamada, Hidenori, Yamamoto, Ken-Ichi   +7 more
core   +1 more source

Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury

Journal of Neuroinflammation, 2020
Background Spinal cord injury (SCI) favors a persistent pro-inflammatory macrophages/microglia-mediated response with only a transient appearance of anti-inflammatory phenotype of immune cells.
H. Fan, Hai-Bin Tang, Zhe Chen, Hu-qing Wang, Lei Zhang, Yu Jiang, Tao Li, Cai-Feng Yang, Xiaoya Wang, Xia Li, Sheng-Xi Wu, Gui-lian Zhang   +11 more
semanticscholar   +1 more source

The Immune Tolerance Role of the HMGB1-RAGE Axis

Cells, 2021
The disruption of the immune tolerance induces autoimmunity such as systemic lupus erythematosus and vasculitis. A chromatin-binding non-histone protein, high mobility group box 1 (HMGB1), is released from the nucleus to the extracellular milieu in ...
Haruki Watanabe, Myoungsun Son
semanticscholar   +1 more source

Harken Not to Wild Beasts: Between Rage and Eloquence in Saruman and Thrasymachus [PDF]

, 2016
One of the giant gaps in Tolkien scholarship has been to miss how deeply Saruman answers the age-old antagonism between rhetoric and philosophy. Like John Milton, Tolkien cannot bring himself to trust rhetoric.
Wise, Dennis Wilson
core   +2 more sources

Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain [PDF]

, 2014
Recent studies indicate that the release of high mobility group box 1 (HMGB1) following nerve injury may play a central role in the pathogenesis of neuropathic pain.
Allette, Yohance M., Due, Michael R., Feldman, Polina, Khanna, Rajesh, Ripsch, Matthew S., White, Fletcher A., Wilson, Sarah M.   +6 more
core   +1 more source

RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.

Cell, 1999
S100/calgranulin polypeptides are present at sites of inflammation, likely released by inflammatory cells targeted to such loci by a range of environmental cues.
M. Hofmann, S. Drury, Caifeng Fu, W. Qu, A. Taguchi, Yan Lu, C. Avila, N. Kambham, A. Bierhaus, P. Nawroth, M. Neurath, T. Slattery, D. Beach, J. McClary, M. Nagashima, J. Morser, David M. Stern, A. Schmidt   +17 more
semanticscholar   +1 more source

Activation and Modulation of the AGEs-RAGE Axis: Implications for Inflammatory Pathologies and Therapeutic Interventions-A Review.

Pharmacological Research
Chronic inflammation is a common foundation for the development of many non-communicable diseases, particularly diabetes, atherosclerosis, and tumors. The activation of the axis involving Advanced Glycation End products (AGEs) and their receptor RAGE is ...
Mengzhou Zhou, Yuyan Zhang, Lin Shi, Liangchao Li, Duo Zhang, Zihao Gong, Qian Wu   +6 more
semanticscholar   +1 more source

Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models

Frontiers in Cardiovascular Medicine, 2020
Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although extensive strides have been made in the treatments for non-diabetic atherosclerosis and its complications, for patients with diabetes, these therapies provide ...
Lander Egaña-Gorroño, R. López-Díez, Gautham Yepuri, L. Ramirez, S. Reverdatto, Paul F. Gugger, A. Shekhtman, R. Ramasamy, A. Schmidt   +8 more
semanticscholar   +1 more source