Results 41 to 50 of about 78,533 (307)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
, 2015 This deliverable comprises the general description of the RAGE project public website – referred also as the RAGE website, accessible at http://www.rageproject.eu.
Beltran, Maria +3 more
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Selfvergifnis – ’n Afgeskeepte area binne die pastoraat
In die Skriflig, 2020 Self-forgiveness – A neglected area within the pastorate: The scientific study of the theme of forgiveness in general, has only begun to gain momentum during the 1970s – it is thus a relatively new concept within the helping professions.
Wentzel C. Coetzer
doaj +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Frontiers in Molecular NeuroscienceOne of the hallmarks of Alzheimer's disease (AD) is the accumulation of beta-amyloid peptide (Aβ) leading to formation of soluble neurotoxic Aβ oligomers and insoluble amyloid plaques in various parts of the brain.
Kseniya B. Varshavskaya +4 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
D6.2 – Summary, Analysis, Road-mapping and Production of Training materials: RAGE – WP6 – D6.2 [PDF]
, 2019 Deliverable 6.2 describes and summarizes the final results of the population of the RAGE Ecosystem portal (EP) with information, knowledge and training material. The core version of the EP and its services are tested and validated.
Hemmje, Matthias +4 more
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Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
D7.3 - Summary Report RAGE Stakeholder Consultation Pocess [PDF]
, 2016 This report presents a summary of the RAGE Stakeholder consultation methodology, process, instruments and activities, which inform parallel work packages in the RAGE project; specifically workpackage 8 (responsible for development of the evaluation ...
Griffiths, Dai +4 more
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