Results 51 to 60 of about 498,772 (347)

Regulating Road Rage

Social & Personality Psychology Compass, 2021
Road rage has been a problem since the advent of cars. Given the ubiquity of road rage, and its potentially devastating consequences, understanding road rage and developing interventions to curb it are important priorities.
J. Bjureberg, J. Gross
semanticscholar   +1 more source

Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamsters

Applied and Environmental Microbiology
Only a few studies have shown that certain probiotics have beneficial effects on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this study, two strains of Bifidobacterium breve, CNCM I-5644 and CNCM I-5979, selected for their ...
Edgar Torres-Maravilla, Marine Wasniewski, Aurélie Wauquier, Alexandre Servat, Evelyne Picard-Meyer, Elodie Monchatre-Leroy, Sandrine Auger, Sophie Holowacz, Franck Boué, Philippe Langella, Elsa Jacouton, Anne-Judith Waligora-Dupriet   +11 more
doaj   +1 more source

Serum Level of Soluble Receptor for Advanced Glycation End Products Is Associated with A Disintegrin And Metalloproteinase 10 in Type 1 Diabetes [PDF]

, 2015
Background The receptor for advanced glycation end products (RAGE) is involved in the pathogenesis of diabetic complications, and soluble forms of the receptor (sRAGE) can counteract the detrimental action of the full-length receptor by acting as ...
Betteridge, DJ, Lam, JKY, Lee, ACH, Shiu, SWM, Tan, KCB, Wong, Y   +5 more
core   +1 more source

Inhibition of the HMGB1/RAGE axis protects against cisplatin-induced ototoxicity via suppression of inflammation and oxidative stress

International Journal on Biological Sciences
As an anti-tumor drug widely used in the clinic, cisplatin is limited by its ototoxic side effects associated with various factors, including inflammatory responses.
Xiangyun Qiao, Wen Li, Zhiwei Zheng, Chang Liu, Liping Zhao, Yingzi He, Huawei Li   +6 more
semanticscholar   +1 more source

Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure

Frontiers in Physiology, 2022
Methylglyoxal (MGO) is a highly reactive dicarbonyl compound implicated in diabetes-associated diseases. In vascular tissues, MGO induces the formation of advanced glycation end products (AGEs) that bounds its receptor RAGE, initiating the downstream ...
Akila L. Oliveira, Matheus L. Medeiros, Mariana G. de Oliveira, Caio Jordão Teixeira, Fabíola Z. Mónica, Edson Antunes   +5 more
doaj   +1 more source

AGE-RAGE Axis and Cardiovascular Diseases: Pathophysiologic Mechanisms and Prospects for Clinical Applications

Cardiovascular Drugs and Therapy
Advanced glycation end products (AGE), a diverse array of molecules generated through non-enzymatic glycosylation, in conjunction with the receptor of advanced glycation end products (RAGE), play a crucial role in the pathogenesis of diabetes and its ...
Bijian Wang, Taidou Jiang, Yaoyu Qi, Sha Luo, Ying Xia, Binyan Lang, Bolan Zhang, Shuzhan Zheng   +7 more
semanticscholar   +1 more source

Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis

Nature Communications, 2021
Accumulating evidence shows that RAGE has an important function in the pathogenesis of sepsis. However, the mechanisms by which RAGE transduces signals to downstream kinase cascades during septic shock are not clear.
Zhengzheng Yan, Hai-hua Luo, B. Xie, Tian Tian, Shan Li, Zhixia Chen, Jinghua Liu, Xuwen Zhao, Liyong Zhang, Yongqiang Deng, T. Billiar, Yong Jiang   +11 more
semanticscholar   +1 more source

RAGE signalling in obesity and diabetes: focus on the adipose tissue macrophage

Adipocyte, 2020
The advanced glycosylation end product receptor (RAGE) acts as a recognition receptor and interacts with different types of ligands that form and accumulate in the tissues and circulation, such as diabetes, inflammation, insulin resistance, and obesity ...
Ziqian Feng, Luochen Zhu, Jianbo Wu
doaj   +1 more source

Unpacking customer rage elicitation: a dynamic model [PDF]

, 2014
Unlike prior research that has confined customer rage to a single point in time, this article explores the unfolding of rage over three time periods, at the initial service failure (Episode 1) and two ineffective service recovery attempts (Episodes 2 and
McColl-Kennedy, Janet, Patterson, Paul, Surachartkumtonkun, Jiraporn   +2 more
core   +1 more source

Receptor for advanced glycation end products and its involvement in inflammatory diseases [PDF]

, 2013
The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily, capable of binding a broad repertoire of ligands. RAGE-ligands interaction induces a series of signal transduction cascades and lead to
Basir, Rusliza, Chuah, Yaw Kuang, Nordin, Norshariza, Talib, Herni, Tie, Tung Hing   +4 more
core   +3 more sources