Results 31 to 40 of about 498,772 (347)

The rage of consent [PDF]

open access: yesCurrent Biology, 2004
Concern about the proprietary rights over human body parts has had a dramatic recent impact in some European countries with many implications for future research.
openaire   +2 more sources

Molecular Characteristics of RAGE and Advances in Small-Molecule Inhibitors

open access: yesInternational Journal of Molecular Sciences, 2021
Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage-associated molecular pattern molecules), such as AGEs, HMGB1, and S100/calgranulins,
Hyeon Jin Kim, M. Jeong, S. Jang
semanticscholar   +1 more source

MLKL Regulates Rapid Cell Death-independent HMGB1 Release in RSV Infected Airway Epithelial Cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Respiratory syncytial virus (RSV)-induced bronchiolitis is a significant contributor to infant morbidity and mortality. Previously, we identified that necroptosis, a pro-inflammatory form of cell death mediated by receptor-interacting serine/threonine ...
Jennifer Simpson   +5 more
doaj   +1 more source

The Development of Maillard Reaction, and Advanced Glycation End Product (AGE)-Receptor for AGE (RAGE) Signaling Inhibitors as Novel Therapeutic Strategies for Patients with AGE-Related Diseases

open access: yesMolecules, 2020
Advanced glycation end products (AGEs) are generated by nonenzymatic modifications of macromolecules (proteins, lipids, and nucleic acids) by saccharides (glucose, fructose, and pentose) via Maillard reaction.
C. Shen   +6 more
semanticscholar   +1 more source

Epidémiologie de la rage et connaissance, attitudes et pratiques des communautés au Burkina Faso

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2020
La rage est une zoonose endémique dans les pays en développement et compte parmi les pathologies virales les plus virulentes et mortelles. Elle constitue une menace pour la sante publique et animale au Burkina Faso.
Madi Savadogo   +8 more
doaj   +1 more source

How should novelty be valued in science? [PDF]

open access: yes, 2014
Box plot analysis of serum concentrations of sRAGE (A), esRAGE (B), S100A9 (C) and HMGB1 (D) in patients with CTEPH (n = 26) and controls (n = 33). Independent Student’s t-test was used to compare groups. RAGE receptor for advanced glycation endproducts,
Ana-Iris Schiefer (547363)   +13 more
core   +4 more sources

Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro

open access: yesJournal of Neuroinflammation, 2020
Background Glial activation and neuroinflammation play a crucial role in the pathogenesis and development of Alzheimer’s disease (AD). The receptor for advanced glycation end products (RAGE)-mediated signaling pathway is related to amyloid beta (Aβ ...
Bo Ding   +9 more
semanticscholar   +1 more source

Drivers’ behaviour modelling for virtual worlds [PDF]

open access: yes, 2013
In this paper we present a study that looks at modelling drivers’ behaviour with a view to contribute to the problem of road rage. The approach we adopt is based on agent technology, particularly multi-agent systems.
Bechkoum, Kamal   +2 more
core   +1 more source

A many-body RAGE theorem [PDF]

open access: yes, 2015
We prove a generalized version of the RAGE theorem for N-body quantum systems. The result states that only bound states of systems with $0\leq n\leq N$ particles persist in the long time average.
Lampart, Jonas, Lewin, Mathieu
core   +5 more sources

Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice

open access: yesScience Translational Medicine, 2021
Description Small-molecule antagonism of RAGE-DIAPH1 reduces diabetes-related complications in mice. Inhibition from the inside Inhibiting the receptor for advanced glycation end products (RAGE) has been shown to reduce complications of diabetes. Instead
M. Manigrasso   +15 more
semanticscholar   +1 more source

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